... been
gained in our understanding of the extremely complex issue of
patient-ventilator interaction in COPD patients. Given the
increasing use of assisted modes, this heightened under-
standing has ... 2)
In the case of assisted ventilatory modes, both the ventilator
and the patient provide the required pressure, equation 1
becoming:
Review
Clinical review: Patient-ventilator i...
... of
PEEP used in the ‘high PEEP’ group was changed during the
study, potentially altering the outcome [20].
Clinical research has proven that large Vts are detrimental in
ARDS. In 2000, findings were ... success
of extubation.
Weaning trials are recommended for patients with prolonged
intubation or cardiopulmonary causes for intubation [45]. In
general, a weaning trial involves reduc...
... lengthened by using higher inspiratory
flow settings (70–100 l/min) during volume cycled ventilation,
using a shorter inspiratory time fraction, reducing respiratory
rate, and eliminating any inspiratory ... Similarly,
when using pressure cycled ventilation, decreasing tidal
volumes may indicate gas-trapping. Other situations in which
clinicians should suspect gas-trapping include increasin...
... kinking is less
of an issue in catheters placed in the subclavian or internal
jugular positions, and that improvements in technology are
being directed at the problem of sheath kinking.
Mini-introducer ... kinking and cracking). The traditional sheath was
composed of Teflon, which is stiffer than polyurethane. The
Cordis AVANTI
®
+ Sheath Introducer is designed to be kink-
resistant by...
... Those investigators showed that, after
RMs, PEEP set at 2 cmH
2
O above the lower inflection point
was more effective in maintaining gas exchange and minimiz-
ing inflammation and lung injury ... sustained inflation. Loop C: PEEP higher
than the lower inflection point after a sustained inflation. Sustained
inflation promoted alveolar recruitment at low PEEP levels (loop B).
Sustained inflat...
... bound to proteins. The two main binding proteins are
the cortisol-binding globulin (CBG) and albumin [1].
Review
Clinical review: Corticotherapy in sepsis
Helene Prigent
1
, Virginie Maxime
2
and ... gluconeogenesis.
Finally, they are involved in bone and mineral metabolism,
activating osteoclasts, inhibiting osteoblasts, decreasing
intestinal calcium uptake and increasing calcium uri...
... training
times and reduced hours of work in the clinical environment,
objective systems are becoming increasingly important
because inexperienced practitioners may fail to recognize
impending ... conditions [13], and is much increased in severely ill
patients who undergo life-saving invasive interventions [14].
Discontinuities in care [15] created by shift working or poor
information...
... M, Madsen CD, Barton CW, Sounders CE, Pointer J: A
randomized clinical trial of high-dose epinephrine and norepi-
nephrine vs standard-dose epinephrine in prehospital cardiac
arrest. JAMA 1992, ... procedures in previous clinical trials when they were
successful in the laboratory [16–18]. In keeping with interna-
tional guidelines, these study protocols called for the use of
the t...
... been demonstrated in clinical studies
[15,25], an in vitro study demonstrated a 10- to 16-fold
increase in the minimal inhibitory concentration of the minocy-
cline–rifampin combination with respect ... for infection, including
vancomycin–heparin and vancomycin–ciprofloxacin–heparin
solutions [42,44]. Because the use of vancomycin is an inde-
pendent risk factor for the acquisition of...
... lower inflexion point is definitively not a
‘magic’ point reflecting the opening pressure of the lung. More-
over, the clinical relevance of the study is high since the lower
inflexion point of ... lung volume change, due to a
PEEP increase, by continuously recording the inspired and
expired tidal volumes as well as changes in peak pressure. An
interesting finding of this study was that P...