... Sawada1, Yuta Kochi2 and Kazuhiko Yamamoto11Department of Allergy and Rheumatology, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan2Laboratory ... detect theIL-32 expression in the synovial lining layers, where monocytes and synovial fibroblasts usually exist. Synovial fibroblasts pro-duce cytokines and proteases, which play an important ... study design, the statistical analysis, and thewriting of the manuscript. YY and AO carried out the cell cul-ture experiments. TS prepared the human samples of synovialtissues and cells. YK...