Báo cáo y học: "Conformational alterations in the CD4 binding cavity of HIV-1 gp120 influencing gp120-CD4 interactions and fusogenicity of HIV-1 envelopes derived from brain and other tissues" pptx
... article as: Gray et al.: Conformational alterations in the CD4
binding cavity of HIV-1 gp120 influencing gp120 -CD4 interactions and
fusogenicity of HIV-1 envelopes derived from brain and other tissues.
Retrovirology ... of 9
SHOR T REPOR T Open Access
Conformational alterations in the CD4 binding
cavity of HIV-1 gp120 influenc...
... activity o ccurring through clustering of
CRDs and multiple carbohydrate binding to the widely-
spaced, repetitive sugars on the surface of pathogens
[6-8]. Upon binding to PAMPs, the MBL pathway and
MASP ... progression of the cascade leads to the activation of C5-9 and to the formation of the
membrane attack complex (MAC), lysing the microbe/cell. Byprodu...
... phenytoin,
phenobarbital, and lamotrigine. The triad of hypersensi-
tivity includes fever, rash and internal organ involvement
with onset of symptoms within 1 to 8 weeks of exposure.
The frequency of the syndrome ... purposes)
of portacaval shunting, thereby decreasing first pass
metabolism; decrease in quantities and affinity of plasma
proteins, thereby increasing f...
... continuously being identified,
and these polymorphisms may play a pivotal role in
sporadic carcinogenesis. A growing body of literature,
including observations of inter-individual differences
in ...
Continued advances in SNP maps and in
high-throughput genotyping methods will facilitate
the analysis of multiple polymorphisms within genes
and the analysis of multi...
... be the start of the protein
coding domain. Sequence analysis of the 3¢ end cDNA
revealed that there is a polyadenylation signal upstream of
the poly(A).
Analysis of the primary structure of
M. ... consist of three subunits, a, b and c,with
the nucleotide -binding and hydrolyzing a subunit defining
the protein’s identity. The a subunit is believed to confer
rece...
... Epidemiology of Allergy Rhinitis. In Epidemiology of
Clinical Allergy. Monographs in Allergy Edited by: Burr ML. Basel, Kargen;
1993:61-79.
4. Slavin RG: Diagnosis and treatment of rhinitis and sinusitis ... atrophy
and drying of the nasal mucous membrane and increased
mucous viscosity. Structural changes in the nose with age
include atrophy of the collagen fibe...
... patients using the RPAS and the
AIMS, the second using the PANSS and the EPSE and the
third using the BARS. Information from the patient's his-
tory, concerning social-demographic and clinical ... symptoms may dominate and overlap the clinical
manifestation of the disease.
According to our results, the severity of physical anhedo-
nia was associated...
... explants, indicating the relevance of both in
vitro systems to study chondrocyte biology on proinflam-
matory stimuli [10,73]. For the in vitro analysis of cartilage
destruction in RA, interactions ... was induced unilaterally in the knee
joint by complete excision of the medial meniscus and
resection of the anterior cruciate ligament and then treated by
intra-...
... (ST) and
synovial fluid (SF). The inflammatory infiltrate consists pre-
dominantly of B lymphocytes, T lymphocytes and macro-
phages in the ST, whereas neutrophils are mainly found in
the SF. The ... on the study
or coordinated the collection of samples in Birmingham,
and contributed to the writing of the manuscript. JM con-
ceived the study, and particip...
... procured the sam-
ples and helped in the analysis of data. GW participated in the
design of the study, analysis of data, and writing of the manu-
script. All authors read and approved the final manuscript.
Additional ... recognition by the immune
system of mitochondrial peptides may be aiding in the recruit-
ment of T cells and inflammatory factors, h...