... research
participants and in public trust in the research enterprise.
Challenges in oversight and monitoring
The lack of effective oversight and monitoring in clinical
research makes it similar in many respects ... monitoring and oversight
for ethical and high quality clinical research.
Keywords critical care research, institutional accountability, institut...
... peptide determinations in critical care medicine: part
of routine clinical practice or research test only?
Paul O Collinson
Department of Chemical Pathology and Department of Cardiology, St George’s ... 0.90).
The Breathing Not Properly study, a multicentre evaluation of
BNP [2], the N-terminal pro-BNP Investigation of Dyspnoea in
the Emergency Department study [3] and the Interna...
... editing and manuscript writing. HK was involved in the
conception and design of study and took an active part in the data analysis
and results interpretation. GO participated to the study conception ... of
Clinical Science, Intervention and Technology, Karolinska Institute, Stockholm,
Sweden.
Authors’ contributions
ARD was involved in the study conception and design, data co...
... different
when examined closely.
27
The T lymphocytes are a
combination of T helper (Th)1 and Th 2 subtypes,
and neutrophils and monocytes are more prominent in
the lesions of chronic urticaria than in the ... ‘‘releasability’’ in atopic and asthmatic individuals. J
Allergy Clin Immunol 1986;78:968–73.
33. Lawrence ID, Warner JA, Cohan VL, et al. Bradykinin analog
induces histam...
... the
alexithymic and 3,31 ± 2,79 years in the nonalexithymic
groups. Persistency of any physical symptom may bring
along alexithymia as a coping strategy. In their paper,
Crook and Tunks (1988) examined ... anxiety in pain patients.
Discussion: Alexithymia may be important in addressing the diversity of subjective factors
involved in pain. The conceptualization of alexithymia as...
... humoral theory was the
most lasting and influencial one for many centuries. In
fact, it influenced the way the diseases and their determin-
ing causes were seen by physicians, thus influencing their
treatment ... provided by
one of its active components, hypericin [23]. Hypericum
extracts inhibit norepinephrine, dopamine and serotonin
reuptake, increasing the concentration and the n...
... Spectrum Laboratory Products Inc.
(Gardena, CA). Polyvinyl alcohol (PVA) was obtained
from Kuraray America Inc. (New York, NY). Glycerin
was obtained from Dow Chemical Company (Midland,
MI). All ... Lactate dehydrogenase and its
isoenzymes in vaginal fluid in vaginitis/vaginosis cases and in healthy
controls. Int J STD AIDS 2003, 14:270-273.
32. Olmsted SS, Meyn LA, Rohan LC, Hillie...
... diabetes and/ or hypertension. In the present
study, we hypothesized that an increasing systemic
proinflammatory burden correlates with dysglycemia
and deregulated blood pressure. We investigated ... suggesting that inflammation precedes
insulin resistance. The vigorous ongoing debate regard-
ing the sequence in which insulin resistance and/ or the
increase in inflammation develop...
... activity can
unhinge the anti-inflammatory and pro-inflammatory
balance favoring inflammation, fostering dysglycemia
(clinical correlate: prediabetes), and disrupting blood
pressure control (clinical ... diabetes and/ or hypertension. In the present
study, we hypothesized that an increasing systemic
proinflammatory burden correlates with dysglycemia
and deregulated blood pressure. We...
... (BDI-II) in individuals with chronic pain. Pain
2008, 137:609-622.
35. Ward E: A Review of Hospital care: Outlining morbidity and mortality
patterns, cost of care & resource inputs. Kingston, ... immunocompetency, and
loneliness in psychiatric inpatients. Psychosom Med 1984, 46:15-23.
41. Laurence B, George D, Woods D: Association between elevated
depressive symptoms and clin...