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Báo cáo y học: " Rapamycin attenuates hypoxia-induced pulmonary vascular remodeling and right ventricular hypertrophy in mice" pptx

Báo cáo y học:

Báo cáo y học: " Rapamycin attenuates hypoxia-induced pulmonary vascular remodeling and right ventricular hypertrophy in mice" pptx

... purposes) Rapamycin reverses hypoxia-induced thickening of the right ventricular wall and hypertrophy of individual cardiomyocytesFigure 6 Rapamycin reverses hypoxia-induced thickening of the right ventricular ... purposes) Rapamycin attenuates hypoxia-triggered thickening of the right ventricular wall and hypertrophy of individual cardiomyocytesFigure 4 Rapamycin attenuates hypoxia-triggered thickening of the right ... citation purposes)Respiratory ResearchOpen AccessResearch Rapamycin attenuates hypoxia-induced pulmonary vascular remodeling and right ventricular hypertrophy in miceRenate Paddenberg†1,...
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Báo cáo y học: " Invasive versus noninvasive measurement of allergic and cholinergic airway responsiveness in mice" doc

... find-ings in the lung in vivo, determination of pulmonary function is an essential tool. Existing methods for measur-ing respiratory function in mice in vivo include invasive and noninvasive ... responsiveness (AR) in intact,spontaneously breathing BALB/c mice.Methods: Using noninvasive head-out body plethysmography and the decrease in tidalmidexpiratory flow (EF50), we determined early AR (EAR) ... physiologically meaningful, noninvasive parameter ofbronchoconstriction for mice and rats [13-17]. No reporthas as yet directly investigated the ability and utility ofrepetitive invasive and noninvasive...
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Báo cáo y học: "Maternal use of Loratadine during pregnancy and risk of hypospadias in offspring"

... number, and the date of drug dispension. Since January 1 1989 all data from North Jutland County have been stored in a prescription database maintained by the Department of Clinical Epidemiology, ... 30 days before conception and six months post-delivery. In the first analysis, cases were defined as boys with hypospadias recorded in the HDR during the first six months post-delivery. The ... second analysis in which we defined cases as boys with hypospadias recorded in the HDR any time post-delivery (some children might have been coded later e.g. at the time of surgery) and controls...
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Tài liệu Báo cáo Y học: Structural determinants of the half-life and cleavage site preference in the autolytic inactivation of chymotrypsin pdf

Tài liệu Báo cáo Y học: Structural determinants of the half-life and cleavage site preference in the autolytic inactivation of chymotrypsin pdf

... sites of chymotrypsin. D-Chymotrypsinogen is achimera constructed to contain a trypsinogen propeptideinstead of the Cys1–Cys122-linked wild-type chymotryp-sinogen peptide. D-Chymotrypsinogen also ... ofmammalian chymotrypsins and trypsins.The enzyme that was used in this study, ratchymotrypsin B, is highlighted by bold type.The loops are boxed and labelled. Chymotryptic and tryptic cleavage ... trypsin mutant with chymotrypsin-like activity (Table 1)was subjected to autolysis and digestion with D-chymo-trypsin and trypsin. Interestingly, despite the presence offour potential chymotrypsin...
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Báo cáo Y học: Expression of glucose transporter-2, glucokinase and mitochondrial glycerolphosphate dehydrogenase in pancreatic islets during rat ontogenesis potx

Báo cáo Y học: Expression of glucose transporter-2, glucokinase and mitochondrial glycerolphosphate dehydrogenase in pancreatic islets during rat ontogenesis potx

... islets and liver of fetal, suckling and adult ratsWe studied the enzyme activities of two protein complexesinvolved in the respiratory chain: succinate dehydrogenase(complex II) and cytochrome ... in the c oncentrations of rat live r cyclic AMP and of serum glucose, free fatty acids, insulin, pancreatic and totalglucagoninthemanandintherat.J. Lat. Clin. Med. 82,957±967.5. Matschinsky, ... secretionof insulin. Bearing this in mind, we determined theactivities of citrate synthase (an enzyme of the Krebscycle re¯ecting the number of mitochondria [10]), succi-nate dehydrogenase and cytochrome...
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Báo cáo y học: "Psychogenic or neurogenic origin of agrammatism and foreign accent syndrome in a bipolar patient: a case report" pdf

... on the brain imaging, involving the left insu-lar and anterior temporal cortex, two brain regions fre-quently involved in aphasic syndrome but also in FAS, acerebrovascular origin must be ... on the brain imaging, involving the left insular and anterior temporal cortex, two brain regions frequently involved in aphasic syndrome but also in FAS, a cerebrovascular origin must be considered ... Spanish-sounding words occasionally and spon-taneously coming to his mind. No meaning is associatedwith these words and the patient easily controls theiroccurrence with no anxiety. Neurological examinationcompleted...
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Báo cáo y học:

Báo cáo y học: "The factor structure of the Strengths and Difficulties Questionnaire (SDQ) in Greek adolescents" potx

... subdimensions(that is, hyperactivity and inattention). This finding mayreflect the inability to assess the multidimensional atten-tion deficit hyperactivity disorder through only five itemsdifferent in nature ... cannot staystill for long' and 'I am constantly fidgeting or squirming'.These findings indicated that the aforementioned itemscreate a subdimension within the hyperactivity/inatten-tion ... problemsscale and had secondary loadings of -0.25 on emotionalsymptoms scale. The item 'I think before I do things' hadloading equal to 0.25 on hyperactivity/inattention scale and a secondary...
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Báo cáo y học: "Efficacy of treatment with glycosaminoglycans on experimental collagen-induced arthritis in rats" pptx

... alterthe binding with selectins because the latter bind severalglycoproteins [53]. HYA and other GAGs could decreasecytokine gene expression directly [54] or indirectly bybinding the CD44 ... Medicine, University of Messina, Messina, Italy3Department of Experimental and Clinical Medicine and Pharmacology, School of Medicine, University of Messina, Messina, ItalyCorresponding author: Giuseppe ... Physiological and Nutritional Sciences, School of Medicine, University of Messina, Messina, Italy2Department of Morphology, Biochemistry, Physiology and Animal Production, School of Veterinary Medicine,...
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Báo cáo y học: "α Does protein kinase R mediate TNF-α- and ceramide-induced increases in expression and activation of matrix metalloproteinases in articular cartilage by a novel mechanism" pps

... metalloproteinase (MMP)expression and activation in the medium were analysed bygelatin zymography, proteoglycan release by thedimethylmethylene blue assay, and cell viability by theCytotox 96®assay. ... c-fos and c-jun and by proinflammatorycytokines that are known to be involved in arthritic dis-eases [4,5], such as interleukin-1 and tumour necrosisfactor α (TNF-α). TNF-α is capable of inducing ... protein synthesis and increased apoptosis, which may also affectcartilage integrity. Increased expression and activation of MMPs, in the absence of a corresponding increase in their inhibitors, would...
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Báo cáo y học:

Báo cáo y học: "β Treatment with recombinant interferon-β reduces inflammation and slows cartilage destruction in the collagen-induced arthritis model of rheumatoid arthritis" ppt

... Phar-macokinetics and pharmacodynamics of IFN-beta 1a in healthy volunteers. J Interferon Cytokine Res 2000, 20:857-866.28. Miyazaki T, Katagiri H, Kanegae Y, Takayanagi H, Sawada Y, Yamamoto A, Pando ... per injection per mouse), limited hyperplasia ofthe intimal lining layer and cell infiltration of the synovial sublining weredetected and a decrease in bone erosions was observed. (b) Infiltrationof ... and/ orretention in the synovial joint.Alternatively, IFN-β may inhibit inflammatory cell infiltrationindirectly, via suppression of FLS and/ or monocyteactivation. Our data demonstrated statistically significantmodulation...
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