Báo cáo y học: "Effect of duloxetine in patients with fibromyalgia: tiredness subgroups" pptx
Báo cáo y học: "Effect of duloxetine in patients with fibromyalgia: tiredness subgroups" pptx
... efficacy of duloxetine did not vary as a function of baseline rat-ings of tiredness, as defined by the FIQ tiredness rating.At baseline, the distribution of tiredness severity in the duloxetine ... demonstrating that theefficacy of duloxetine in the treatment of pain in patients with fibromyalgia is not associated with baseline tiredness levels.Analyses of the PGI-Improvement produced findingssimilar ... patients with fibromyalgiato test the hypothesis t hat baseline ratings of tiredness would be negatively associated with the efficacy of duloxetine on measures of pain and functional ability in patients...
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Báo cáo y học: "Pharmacokinetics of epinephrine in patients with septic shock: modelization and interaction with endogenous neurohormonal status" pdf
... decrease in endog-enous norepinephrine concentrations during epinephrine infu-sion has not been described previously. An epinephrine-induced inhibition of norepinephrine release from sympatheticneuronal ... in endogenous norepinephrine sug-gests the absence of accessory metabolic pathways convert-ing exogenous epinephrine to norepinephrine.The influence of BW and disease severity on epinephrinepharmacokinetics ... toepinephrine may be due to pharmacodynamic factors or to non-linear pharmacokinetics. The purpose of this study was toinvestigate the pharmacokinetics of epinephrine and itsdeterminants in patients...
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Báo cáo y học: "Effect of levosimendan in experimental verapamilinduced myocardial depression" pot
... then induced by along-lasting intravenous infusion containing 2.5 mg/ml of verapamil at an escalating rate into the right internal jug-ular vein. The rate of verapamil infusion was increased by2.5 ... ketamine 10 mg/kgand fentanyl 5 μg/kg intramuscularly was followed bycannulation of an ear vein and intravenous administra-tion of 2 mg/kg of propofol for tracheotomy. Anesthesiawas maintained ... contraction byimproving the use of available calcium rather by inundat-ing the cell with excessive calcium [21]. The use of tradi-tional inotropes is associated with increased energyconsumption...
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Báo cáo y học: "Effect of allergen-specific immunotherapy with purified Alt a1 on AMP responsiveness, exhaled nitric oxide and exhaled breath condensate pH: a randomized double blind study" ppsx
... These findings should no n ecessarily beinterpreted as demonstrative of the lack of clinical effi-cacy, because immunotherapy-induced changes in air-way responsiveness or in inflammatory markers ... ≥3mm larger in diameter than that of the glycerinatedsaline.Data analysisAn intention-to-treat approach was followed in the ana-lysis of efficacy data. All patients with a baseline and atleast ... alternata.A favourable safety profile was demonstrated. Themajority of the reactions involved erythema and swelling in the vicinity of the injection sites consistent with localallergic reactions...
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Báo cáo y học: "Control of hyperuricemia in subjects with refractory gout, and induction of antibody against poly(ethylene glycol) (PEG), in a phase I trial of subcutaneous PEGylated urate oxidase" potx
... employs a succinyl linker, with mPEGslinked to glycine by means of a carbamate bond, and with PEGs unlinked to any amino acid.It is unclear whether systematic testing for anti-PEG antibodyhas been ... deaminase in patients with adenosine deaminasedeficiency. J Clin Invest 1992, 89:1643-1651.27. Hershfield MS: Biochemistry and immunology of poly(ethyleneglycol)-modified adenosine deaminase (PEG-ADA). ... anti-PEG-uricase antibody. By contrast,PEG-uricase itself completely inhibited the ELISA, as did 10 KmPEG-glycine, the PEG moiety of PEG-uricase conjugated with glycine instead of enzyme. (In a similar...
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Báo cáo y học: "Switching TNF antagonists in patients with chronic arthritis: an observational study of 488 patients over a four-year period" pps
... efficacy [13]. In another study, improvement wasobserved in 20 patients replacing etanercept with infliximab[14]. The efficacy and safety of four infusions of infliximab in patients failing to respond ... efficacy of switching from etanercept to infliximab in patients with rheu-matoid arthritis. J Rheumatol 2004, 31:1098-1102.15. Efficacy and toxicity of infliximab (remicade) in patients with rheumatoid ... well [15]. Finally, improvement in inflammation parameterswas seen in 12 of 14 patients switching from infliximab toetanercept in another recent study [16]. Information regardingswitching to or...
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Báo cáo y học: "Serum IL-15 in patients with early systemic sclerosis: a potential novel marker of lung disease" potx
... concentrations of IL-15 in patients with systemic sclerosis increase compared with healthy control individualsSerum concentrations of IL-15 in patients with systemic sclerosis increase compared with healthy ... and coordination of the study, in the interpretation of the data and in the revision of manuscript. AA participated in the design and coordination of the study, in the interpreta-tion of the data ... correlated inversely with the systolic blood pressure bymultiple linear regression analysis including variables that mayinfluence the systolic blood pressure (Table 3). Age and thebody mass index...
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Báo cáo y học: "Quality of life in patients aged 80 or over after ICU discharge" pps
... autonomy, and quality of life of elderly patients with a long-term intensive care unit stay. Crit Care Med 2000,28:3389-3395.7. Sjogren J, Thulin LI: Quality of life in the very elderly after ... differences. In contrast, one-yearand two-year mortality rates have usually been withinthe 60% to 70% range [9,22-26], in line with our results.Our relatively high ICU mortality rate was explained bythe ... in the present study. Differences in preferences of elderly patients may arise because of varia-tions over time [31-33], most notably increased vulnerabil-ity [34] and family burden [35]. Patients...
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Báo cáo y học: "Quality of life in patients aged 80 or over after intensive care unit discharge" pdf
... are subsequently discharged. Indeed, referring elderly patients to a specialized geriatric unit would probably increase their chances of recovery [3]. e existence of promising interventions ... the ICU because of the high mortality of these patients. As our selection criteria and triage models improve, we are dealing with a greater number of elderly patients in good physical health. ... improvement in the selection process by trying to understand the opinion and desires of the patient. is is the subject of ongoing research in our team.We agree that the balance between the suff ering...
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Báo cáo y học: "Line bisection performance in patients with generalized anxiety disorder and treatment-resistant depressionLine bisection performance in patients with generalized anxiety disorder and treatment-resistant depression"
... PI in the Department of Clinical Psychology and Psychiatry, Zhejiang University School of Medicine. His current team work includes the clin-ical psychology and clinical psychiatry, being ... Department of Clinical Psychology and Psychiatry, Zhejiang University School of Medicine, Hangzhou, China; 3. Department of Psychiatry, Second Hospital, Zhejiang University School of Medicine, Hangzhou, ... associa-tion of left hemisphere predominance and risk-taking in healthy university students has also proven by studying the line bisecting performance and Zucker-man’s sensation seeking scales in Drake...
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