Báo cáo y học: " Cyclic hydrostatic pressure and cotton particles stimulate synthesis by human lung macrophages of cytokines in vitro" pptx
Báo cáo y học: " Cyclic hydrostatic pressure and cotton particles stimulate synthesis by human lung macrophages of cytokines in vitro" pptx
... purposes)Respiratory ResearchOpen AccessResearch Cyclic hydrostatic pressure and cotton particles stimulate synthesis by human lung macrophages of cytokines in vitroSarah Lewis1, Dave Singh2 and Carol ... examines the effect of cyclic hydrostatic pressure and cotton particles on synthesis of cytokines by human alveolar macrophages. Methods: Alveolar macrophages were obtained from patients with lung ... Exposure to cotton particles stimulated cytokine synthesis by macrophages from all threesources; exposure to cyclic hydrostatic pressure alone did not stimulate cytokine synthesis significantly. However,...
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Báo cáo y học: " Cyclic hydrostatic pressure and cotton particles stimulate synthesis by human lung macrophages of cytokines in vitro" ppsx
... purposes)Poly(I:C) induces a dose dependent influx of inflammatory cells into the airways of miceFigure 1Poly(I:C) induces a dose dependent influx of inflammatory cells into the airways of mice. ... comparisons.ResultsPoly(I:C) induces a marked inflammatory response in the lungs of miceIntranasal administration of three once-daily doses of poly(I:C) resulted in a dose-dependent inflammatory cellinflux into the lung. ... pro-inflammatory cytokines in the lungs following viral infection representsa crucial step in promoting the inflammatory response in various lung diseases [7,8]. A better understanding of theeffects...
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Báo cáo y học: "Communication between secondary and primary care following self-harm: are National Institute of Clinical Excellence (NICE) guidelines being met" ppsx
... Content of communications from secondary services to primary care services according to recommendations by Royal College of Psychiatrists (2004)Type of information Any communication, including ... National Institute for Clinical Excellence: Self-harm: the short-term phys-ical and psychological management and secondary prevention of self-harm in primary and secondary care. Clinical guideline ... Institute of Clinical Excellence (NICE) guidelines being met?Jayne Cooper*1, Elizabeth Murphy1, Rita Jordan2 and Kevin Mackway-Jones3Address: 1Community Based Medicine, Department of Psychiatry,...
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Báo cáo y học: "Targeted genomic capture and massively parallel sequencing to identify genes for hereditary hearing loss in middle eastern families" pot
... Tables of indels and SNPs in four or moreprobands in our population. (a) Table of indels appearing in four ormore probands in our population (n = 11). (b) Table of SNPs in four ormore probands in ... damaging by Polyphen2 and SIFT (Tables 2 and 3).WFS1Family K13576 is of Ashkenazi Jewish origin. Hearingloss in the family is dominant (Figure 2). Audiograms of affected relatives reveal hearing ... novelvariants in MYO15A (Tables 2 and 3). The first variant,corresponding to MYO15A c.8183G > A (p.R2728H),was supported by 50% (43/86) of reads and is predictedto be damaging by PolyPhen2 and SIFT....
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Báo cáo y học: "Noninvasive positive pressure ventilation for respiratory failure caused by exacerbations of chronic obstructive pulmonary disease: a standard of care" ppt
... accepted as a standard of care, then thismeans that a substantial minority of institutions in Europe, and undoubtedly in the USA as well, are not offering therapythat meets current standards. Efforts ... establishing the efficacy of NPPV to the refinement of selection and application techniques with the aim of minimizing the failure rate. Potential reasons for failureinclude selection of inappropriate ... pulmonary edema,evidence clearly indicates that noninvasive positive pressure techniques are effective at promptly reducing dyspnea,improving oxygenation, and avoiding intubation [7], but it isnot...
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Báo cáo y học: "Qualitative network models and genome-wide expression data define carbon/nitrogen-responsive molecular machines in Arabidopsis" potx
... involved in proteinfate (for example, protein folding, sorting and degradation)were induced by C independent of N (model 2). In addition,77 other genes related to protein synthesis were induced by ... also by C in interaction with N. Components of the proteasomewere induced by C independent of N, and also by C in interac-tion with N. Other cellular processes controlled by C, N or CNinteractions ... avariety of data, including: Arabidopsis metabolic pathways;known protein-protein, protein-DNA, and miRNA-RNAinteractions; and predicted protein-protein and protein-DNAinteractions (described in...
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Báo cáo y học: "TPO, but not soluble-IL-6 receptor, levels increase after anagrelide treatment of thrombocythemia in chronic myeloproliferative disorders"
... Lacey D, Hill D, Chen Y, Fletcher F, Hawley RG, McNiece IK A model of myelofibrosis and osteosclerosis in mice induced by overexpressing thrombopoietin (mpl ligand): reversal of disease by bone ... R, Takayama T, Kato J, Yamauchi N, Ko-gawa K, Sakamaki S, Hirayama Y, Kohda K, Niitsu Y. Involve-ment of transforming growth factor-beta and thrombopoietin in the pathogenesis of myelodysplastic ... Giraudier S, Vainchenker W, Wendling F. Prominent role of TGF-beta 1 in thrombopoi-etin-induced myelofibrosis in mice. Blood 2002;100:3495-503 32. Erusalimsky JD, Franklin R and Hong Y. Is the...
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Báo cáo Y học: SF2/ASF protein inhibits camptothecin-induced DNA cleavage by human topoisomerase I potx
... &Tazi, J. (1998) Interaction between the N-terminal domain of human DNA topoisomerase I and the arginine-serine domain of its substrates determines phosphorylation of SF2/ASF splicingfactor. Nucleic ... 3. Binding of htopo I and SF2/ASF to DNA revealed by mobilityshift assay. (A) Binding of htopo I to DNA. Lanes: 1, DNA alone;2, DNA + 0.14 pmol htopo I. (B) Aggregation of DNA by htopo I and ... phos-phorylated in the preparation used in the cleavage assay asÔphosphorylated SF2/ASFÕ.The amount of htopo I and SF2/ASF was quantified by densitometric scanning of SDS-polyacrylamide gels usingBSA...
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Báo cáo y học: " Numbers needed to treat calculated from responder rates give a better indication of efficacy in osteoarthritis trials than mean pain scores" pptx
... limited by size, and by examining onlyone trial. Validation would require calculations to be performedon a larger set of trials using individual patient data not availa-ble in publications, and ... analgesics. Pain 2006, 121:1-5.11. Moore RA, Edwards JE, McQuay HJ: Acute pain: individualpatient meta-analysis shows the impact of different ways of analysing and presenting results. Pain 2005, ... better indication of efficacy in osteoarthritis trials than mean pain scoresR Andrew Moore1, Owen A Moore2, Sheena Derry1 and Henry J McQuay11Pain Research and Nuffield Department of Anaesthetics,...
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Báo cáo y học: " Inflammatory parameters predict etiologic patterns but do not allow for individual prediction of etiology in patients " ppsx
... Thestudy monitor of the LCC includes the patient in CAP-NETZ by applying the following criteria: age ³ 18 years, apulmonary infiltrate diagnosed by chest x-ray, clinicalsymptoms consisting of ... outpatients and inpatients.The application of more invasive procedures such as bron-choscopy including bronchial washing and brushing isnot feasible and realistic in such a study and was thereforeomitted. ... helping clinicians – in combination with scoring systems- to identify clinicallyrelevant infections, to assess a patient's risk profile, and toPublish with BioMed Central and every scientist...
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