... may be systematically differentfrom most. Although this is the concern of generalizabil-ity from any type of research, organizations that partici-pate in randomized and controlled trials may ... myocardialinfarction treated by primary angioplasty. J Am Coll Cardiol2003, 42:991-997.62. McNamara RL, Herrin J, Bradley EH, Portnay EL, Curtis JP, Wang Y, Magid DJ, Blaney M, Krumholz HM: Hospital ... novo discoveryefforts that periodically can fully shift the paradigm of anindustry in ways not possible through the study of onlypositive deviance.Ultimately, there are two major differences...