Báo cáo y học: " Biomarkers of systemic inflammation and depression and fatigue in moderate clinically stable COPD" pdf

... between systemic inflammation and symptoms of depression and fatigue in patients with mainly moderate and clinically stable COPD using a range of inflammatory biomarkers, 2 depression and 2 fatigue ... between systemic inflammation and symptoms of depression and fatigue in patients with mainly moderate and clinically stable COPD using a range of inflammatory biomarkers, two depression scales and ... activity [6], and substantial impairment in quality of life [8].The association between symptoms of depression and fatigue and systemic inflammation has been examined in depth in healthy individuals...

Báo cáo y học: " Effect of acute hypoxia on respiratory muscle fatigue in healthy humans" doc

... respiratory muscle fatigue independently,at least in part, of its effects on the ventilatory respo nse and the relative leg work intensity during whole-bodyexercise.Diaphragm fatigue following inspiratory ... limitations in hypoxia.The potential systemic impact of increase d respiratorymuscle fatigue is illustrated in the present study by thehigher HR response in hypoxia compared to normoxic and hyperoxic ... effect of hypoxia on expiratory muscle fatigue. Diaphragm fatigue following whole body exercise in hypoxiaSeveral studies evaluated the effect of hypoxia on dia-phragmfatiguebycomparingtheamountoffatigueobserved...

Báo cáo y học: " Characterization of protein tyrosine phosphatase H1 knockout mice in animal models of local and systemic inflammation" docx

... is under stringent regulation.Tyrosine phosphorylation is a central mechanism in thecontrol of key signaling proteins involved in innateimmunity. The role of protein tyrosine kinases (PTKs)has ... Characterization of protein tyrosine phosphatase H1 knockout mice in animal models of local and systemic inflammation Journal of Inflammation 2010, 7:16Patrignani et al. Journal of Inflammation ... to NFκB pathway activation and IL8 pro-duction [25,26]. CARR injection in the hind paw of themouse is one of the most commonly used models of inflammation and inflammatory pain and it has a...

Báo cáo y học: "Biomarkers of inflammation, coagulation and fibrinolysis predict mortality in acute lung injury" doc

... syndromeBiomarkers of inflammation in acute lung injury and acute respiratory distress syndrome. Comparison of plasma levels of biomarkers of inflammation in 50 patients with acute lung injury and ... Mann–Whitney U test.Figure 2 Biomarkers of disordered coagulation and fibrinolysis in acute lung injury and acute respiratory distress syndromeBiomarkers of disordered coagulation and fibrinolysis in ... acute lung injury and acute respiratory distress syndrome. Comparison of plasma levels of biomarkers of disordered coagulation and fibrinolysis in 50 patients with acute lung injury and acute...

Báo cáo y học: " Biomarkers for systemic lupus erythematosus: has the right time finally arrived" pdf

... moremechanistically inclined papers on SLE and immunology and imputing the utility of aspects of pathogenesis to theclinic. This comprehensive overview identifies possible,promising, and unlikely biomarkers ... apply them. The review of theliterature was done by traditional methods: searching bykey words and search engines, scouring the reference lists and doing deeper-level searches, and reading ... process; (2)identifying aspects of pathogenesis that can be reliably and relatively easily determined; and (3) ascertaining thatthere is a close relationship between the marker and theoutcome...

Báo cáo y học: "Biomarkers of endothelial dysfunction, cardiovascular risk factors and atherosclerosis in rheumatoid arthritis" pptx

... for determination of cytokines and biomarkers of endothelial dysfunction were stored at -70°C before laboratory testing. Cytokines and adhesion mole-cules were measured using enzyme-linked immunosorbentassays ... refused, and the remaining 74were included. Patients receiving lipid-lowering and antidia-betic medications were excluded. The baseline clinical and routine laboratory characteristics of the included ... previously reported[26]. Although 10 patients were on thyroxine replacementtherapy and eight had subclinical hypothyroidism (thyrotropin>4 µIU/ml and normal thyroxine levels) [27], none had clinicalhypothyroidism...

Báo cáo y học: "Activation of transforming growth factor-β1 and early atherosclerosis in systemic lupus erythematosus" pptx

... patient and con-trol individuals on entry into the study. A study of the variation in TGF-β1 AI over time and with disease activity and treatment in SLE patients is beyond the scope of the ... and helped to draft the manuscript. YAobtained consent from patients and collected the samples and patient data for the study, and participated in the coordination of the study and writing of ... ActivityIndex (SLEDAI) [12]. Therapy was recorded, including currentdose of steroids and antimalarial drugs. Damage wasassessed using the American College of RheumatologySLICC (Systemic Lupus International...

Báo cáo y học: "Pathogenesis of tendinopathies: inflammation or degeneration" ppt

... cells) and bNOS (found in brain and neuronal tissue) are constitutive and important in blood pressure regulation and memory; iNOS is an isoformthat can be induced by pro-inflammatory cytokines and ... by the release of inflammatory and growthsubstances, both in the general circulation and locally in tendons: among them is interleukin-1β, which in turn results in the increased expression of ... that occur in experimental and humanTPs. Finally, we propose a unifying theory, drawn from bothexperimental and clinical data.Anatomy and physiologyThe tendons are made up of bundles of collagen...

Báo cáo y học: "Biomarkers as tools for improved diagnostic and therapeutic monitoring in systemic lupus erythematosis" potx

... activity biomarkers has been remarkable and many potential new indicators of lupus activity have beenrecently uncovered. Many of these novel biomarkers are onlynow beginning to be evaluated in clinical ... Dan-Rong Y, Xiao-Qing T, Hao W, Hong-Lian G, Xian-TaoK, Ren-Qian Z, Jiyu L: Preliminary clinical measurement of theexpression of B-cell activating factor in Chinese systemic lupus erythematosus ... upregulation of a group of IFN-stimulated genes in lupus patients [18].This gene signature is characterized by the highly co-ordinated upregulation of type I IFN-inducible inflammatorycytokines,...

Báo cáo y học: " Diagnosis of systemic toxoplasmosis with HIV infection using DNA extracted from paraffinembedded tissue for polymerase chain reaction: a case report" pptx

... embedded in paraffin wax afterdehydration which was cut into 3 μm-thick sec tions, and routinely stained wi th hematoxylin and eosin doublestain. Histopathological examination indicated hypocellu-lar ... radiography and computedtomography (CT) of the brain showed no abnormalities.He was diagnosed as purulent meningitis, initially,because of an increasin g of neutrophils count in cere-brospinal ... only defini-tive hosts of T. gondii, but humans can be infected bythe ingestion of oocysts or tissue cysts [4]. T. gondiiinfection is generally asymptomatic or associated withlymphadenopathy...

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