... is properly cited.
Research article
Phenotypic and functional abnormalities of bone
marrow-derived dendritic cells in systemic lupus
erythematosus
Ying J Nie
1
, Mo Y Mok
1
, Godfrey CF Chan
2
, ... BMDCs, bone marrow-derived dendritic cells; BMCs, bone
marrow cells; FLDCs, dendritic cells induced by FL; mDCs, myeloid dendritic cells; FL, FMS-like ty...
... 2c–e). In
the former, CCR7 expression was detected mostly in the
perivascular lymphocytic infiltrates of the sublining layer
(Fig. 2b,o) and, only occasionally, in scattered cells in the
sublining ... at the level of lymphocyte aggre-
gates (Fig. 2e,f).
Conversely, CCR5-positive cells were detected mainly in
the lining layer and in the sublining zone of the superficia...
... A: Bone marrow-derived mesenchymal stem cells
induce both polyclonal expansion and differentiation of B cells
isolated from healthy donors and systemic lupus erythemato-
sus patients. Stem Cells ... Chemokine and chemokine
receptor analysis reveals elevated interferon-inducible pro-
tein-10 (IP)-10/CXCL10 levels and increased number of
CCR5+ and CXCR3+ CD4 T cells...
... are depleted of PyPu dinucleotides
immediately upstream of the dominant TSS [-1,+1] (namely, [-2,-1] and [-3,-2]; fraction of PyPu dinucleotides shown as grey bars) and have a PyPu
consensus ... spacing influences initiation site usageFigure 4
TATA-TSS spacing influences initiation site usage. Histogram showing the
distribution of the four possible dinucleotides (PyPu, PyPy, Pu...
... trypsin, untreated AFP (UT AFP), and deglycosylated AFP (DG) are id entified.
Bands smaller than 1 4 kDa in lan es containing trypsin were shown to b e trypsin autolysis products (trypsin-only ... [19].
Dimerization of smelt AFP is unlikely to increase activity
by increased ice binding because only a dimer with perfectly
aligned ice-binding sites would have enhanced binding to ice
and...
... of cytokines in activation and function
of
γδ
γδγδ
γδ
T cells activated indirectly through cytokines
secreted by ab T cells, accessory cells and antigen
presenting cells (APC). Cytokines were ... removal of
γδ
T cells early in cultures leads
to greater proliferation of CD4
+
cells and facilitates cloning
Phenotypic and functional analysis of bovine
γδ...
... certain inflammatory cytokines (IL-6, IL-1β) and
by certain growth factors.
Extracellularly, TIMPs inhibit MMP activity by forming high-
affinity noncovalent complexes with MMPs. The amino-termi-
nal ... amino-termi-
nal domain of TIMP binds the active site of MMPs, inhibiting
their proteolytic activity. The carboxy-terminal domain of cer-
tain TIMPs has also the ability to form compl...
... orders of magnitude to fit into
the space available [1,2], and the mechanism of chromo-
somal packing in bacteria and the proteins involved is a
long-standing question. In a recent study published ... analyzed and understood
together. Nucleoid topology is strongly related to the
binding patterns of NAPs. All the major NAPs, with the
exception of Dps (the DNA-binding pro...
... positive ly correlates with the increasing
concentration of DHPC.
Protein-lipid interactions and Protein-LDLR binding of
ApoE-(72-166) Proteins
To identify and compare the lipid binding ability of the
three ... three isoforms were significantly dissociated in the presence of dihexanoylphosphatidylcholine.
Dimyristoylphosphatidylcholine turbidity clearance assay showed that apoE4...
... splicing machinery very efficiently by using the Rev
protein which binds with high affinity and specificity to
highly structured cis-acting RNA element present within
the coding region of HIV-1 ... etic diversity and has been
classified into various subtypes and recomb inant forms.
While subtype B predominates in US and UK, it is sub -
type C that is predominant in India, China...