... [1] and code for an extremely con-served 10 kDa protein. The Chlamydomonas, Caenor-habditis elegans, Drosophila and mammalian LC8orthologs share more than 90% identity. The twomammalian paralogs ... Journal compilation ª 2011 FEBS88 Haraguchi K, Satoh K, Yanai H, Hamada F, Kawabu-chi M & Akiyama T (2000) The hDLG-associated pro-tein DAP interacts with dynein light chain andneuronal nitric ... methyltransferase, is the only LC8partner in our list that we now consider as false-posi-tive. It was identified as an LC8 partner from rat brainby affinity chromatography and by pepscan analysis[12,62];...