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Báo cáo y học: " Breast conserving surgery with preservation of the nipple-areola complex as a feasible and safe approach in male breast cancer: a case report" pptx

Báo cáo y học:

Báo cáo y học: " Breast conserving surgery with preservation of the nipple-areola complex as a feasible and safe approach in male breast cancer: a case report" pptx

... operation, and organised the primary management plan of the patient.He supervised the writing and editing of the paper. All the authors have read and approved the final version of the manuscript.ConsentWritten ... FBC: female breast cancer; FNA: fine needle aspiration; IDC: invasive ductalcarcinoma; MBC: male breast cancer; SNB: sentinel nodebiopsy; US: ultrasound.Competing interests The authors declare ... on both fine needle aspiration (FNA) and corebiopsy. The tumour was a grade 2 invasive ductal carci-noma (IDC). Investigations did not show any distantmetastases. The patient was offered modified...
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Báo cáo y học: "Two-dose-level confirmatory study of the pharmacokinetics and tolerability of everolimus in Chinese patients with advanced solid tumors" pps

... preclinical and clinicalpharmacokinetic and pharmacodynamic data. J Clin Oncol 2008,26:1596-1602.17. Okamoto I, Doi T, Ohtsu A, Miyazaki M, Tsuya A, Kurei K, Kobayashi K,Nakagawa K: Phase ... the patient with breast cancer.PharmacokineticsAbsorption of everolimus after oral administration wasrapid to moderate with a median Tmax of 3.0 h in the 5mg/daycohortand2.0hinthe10mg/daycohort(Figure ... safe ty, and efficacy of the oral mammalian target of rapamycin inhibitor everolimus in Chinese patients with advancedsolid tumors.Methods: A total of 24 patients with advance d breast cancer...
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Báo cáo y học: "Umbilical hernia rupture with evisceration of omentum from massive ascites: a case report" pdf

... changes of intra-abdominal pressure, such as a sudden increase in ascites combined with s training forstoolasinthiscasereport,itmayovercometheelasti-city of the abdominal wall and lead to hernias ... We report the case of a patient with a history of alcoholic liver disease with ascites. Ascites causes a chronic increase in intra-abdominal pressure. A sudden increase in intra-abdominal pressure, ... report of an acute rise in intra-abdominal pressure from straining for stool as the cause of a ruptured umbilical hernia. Case presentation: An 81-year-old Caucasian man with a history of alcoholic...
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Báo cáo y học: "Patent vitellointestinal duct with prolapse of inverted loop of small intestine: a case repo" pdf

... Figure3). The distal loop entering into the umbilicus was slowlypulled inside the peritoneal cavity with extreme delicacyto find that the outer loop was diminishing in size and finally disappeared ... purposes)general anesthesia. A small transverse incision of 4 cen-timeters was made just below the umbilicus. The outersurface of the emerging loop was firmly adherent to all the layers of the anterior abdominal ... resection of the loop of intestine near the patent duct followed by primary anastomosis. If the patient arrives late with gross edema or the viability of the intestinal loops is in question then exteriorization...
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Báo cáo y học: "Granulomatous cheilitis associated with exacerbations of Crohn''''s disease: a case report" potx

... an earlyclinical index of the recurrence of the intestinal disease as well. Case presentation: A man aged 25 was admitted in our department on August 1999 with chronicdiarrhea and loss of weight. ... of the lip swelling.DiscussionOrofacial granulomatosis is a term generally used todescribe swelling of the orofacial area, mainly the lips, sec-ondary to an underlying granulomatous inflammatoryprocess. ... notonly in improvement of bowel symptoms but also in diminishment of the size of the lip swelling. Anotherpoint of interest was the fact that granulomatous cheilitiswas the only extraintestinal...
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Báo cáo y học: "Successfully treated synchronous double malignancy of the breast and esophagus: a case report" pot

... carci-noma of the esophagus and the breast at the same time. In this case, the histopathology of the breast tumor wasan infiltrating ductal carcinoma grade II and the histopa-thology of the esophageal ... double malignancy of breast and esophageal carcinomas can be found. Breast carcinoma represents one of the most common origins of metastasis to the esophagus [7]. The common sites of metastasis ... porta hepatis was also free of lymph nodes.Significant lymphadenopathy was seen along the celiactrunk and the lesser curvature of the stomach along the gastric artery. The para-aortic and para-caval...
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Báo cáo y học:

Báo cáo y học: "Undifferentiated giant cell type carcinoma of the gallbladder with sarcomatoid dedifferentiation: a case report and review of the literature" ppsx

... the neck of the gallbladder, thusleading to the clinical presentation and the imaging and intra-operative findings of gallbladder empyema in ourpatient. Incidental finding of gallbladder carcinoma ... 10.9% of gallbladder carcinomas [1].Among undifferentiated gallbladder carcinomas, giant celltype carcinomas may also rarely be encountered; in suchcases, it is assumed that anaplastic giant ... identified intra-operatively during the assessment of the peritoneal cavity,including lymphadenopathy and liver or peritoneal pathol-ogy. Based on the pre-operative as well as the intra-operativefindings,...
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Báo cáo y học:

Báo cáo y học: "Perivascular epitheloid cell tumour (PEComa) of the retroperitoneum – a rare tumor with uncertain malignant behaviour: a case report" ppsx

... neces-sary in these patients. The association between LAM and PEComas as a family and the co-occurrence in an individual patient is wellknown. It could be speculated that these patients mayhave a ... outcome of this disease can be devastating, yet the aetiology and effective treatments are unknown. Firmcriteria for malignancy and proper subclassifications of PEComas have yet to be established and ... compatible with LAM. Case presentation A 27-year-old woman, who first complained of upperabdominal pain, was referred from a local clinic with the impression of a retroperitoneal haematoma after...
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Báo cáo y học: " Rationale for one stage exchange of infected hip replacement using uncemented implants and antibiotic impregnated bone graft"

... approaches may be found in the quality of the surgical debridement and dead space management 71. Dead space management is performed by a new prosthesis the same as with a spacer with the addi-tional ... two-stage exchange arthroplasty has been claimed being the gold stan-dard for treating infection, mostly in combination with spacers in the form of antibiotic loaded poly-methylmethacrylate ... (PMMA). But there are no evi-dence based publications, no randomized data and only few metaanalyses available on the topic. Many protocols base on assumptions making the treatment “more art...
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Báo cáo Y học: ATP stimulates MDM2-mediated inhibition of the DNA-binding function of E2F1 pot

Báo cáo Y học: ATP stimulates MDM2-mediated inhibition of the DNA-binding function of E2F1 pot

... interaction of the N-ter-minus of MDM2 with the N-terminus of p53, and aninteraction of the acid domain of MDM2 with the central domain of p53 [24]. Accordingly, ligands such as the NUTLIN and BOX1 ... MDM2play a mechanistic role in binding to E2F1 and alter-ing its function in a DNA-binding assay. To ensurethat the inhibition of E2F1 DNA-binding functionis not a result of a contaminating chaperone ... betweenE2F1 and MDM2 was evaluated by changes in partialproteolysis of E2F1. Increasing the duration of trypsin-ization resulted in a relatively rapid degradation of full-length E2F1 (Fig. 5A) , with accumulation...
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