Báo cáo y học: " Kaposi''''''''s sarcoma of the hand mimicking squamous cell carcinoma in a woman with no evidence of HIV infection: a case report" pptx
Báo cáo y học: " Kaposi''''s sarcoma of the hand mimicking squamous cell carcinoma in a woman with no evidence of HIV infection: a case report" pptx
... lesion wasinitially regarded as a squamous cell carcinoma. The lesion's clinical presentation, its location, the otherwisenormal skin, and the lack of any predisposing factors with the exception ... 1 A primary Kaposi's sarcoma on a hand, which was first regarded as a squamous cell carcinoma. A wide and deep total excision of the lesion was performed and a full-thickness skin graft ... evaluation, no further treatment modalities wereconsidered necessary. During a 9-month follow-up, no A primary Kaposi's sarcoma on a hand, which was first regarded as a squamous cell carcinomaFigure...
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Báo cáo y học: " Kaposi''''s sarcoma associated herpes virus-encoded viral FLICE inhibitory protein activates transcription from HIV-1 Long Terminal Repeat via the classical NF-κB pathway and functionally cooperates with Tat" pptx
... have carriedout a detailed analysis of the ability of K13 to activate the HIV- 1 LTR and analyzed the contribution of the canonicalvs alternate NF-κB signaling pathways, various subunits of the ... NF-AT,USF and AP1. Among the various signaling pathwaysknown to activate HIV- 1 LTR, the NF-κB pathway is partic-ularly important as it is activated by several cytokinesinvolved in immune and ... by conversion of an NF-kappaBenhancer element into a GABP binding site. J Virol 1999,73:1331-40.61. Yamamoto Y, Yin MJ, Gaynor RB: IkappaB kinase alpha (IKKa-lpha) regulation of IKKbeta kinase...
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Báo cáo sinh học: " Kaposi''''s sarcoma associated herpesvirus G-protein coupled receptor activation of cyclooxygenase-2 in vascular endothelial ce" pptx
... pcDNA3vector alone displayed minimal COX-2 promoter activityat each amount analyzed in these experiments. Activation of the cellular promoter should lead to increased mRNAsynthesis and this was the case. ... Relative quantitation was determined using the comparative CT method with data normalized to 36B4mRNA and calibrated to the average ΔCT of untreated con-trols.Statistical analysisData are ... Cincinnati, OH 45267, USA and 5Department of Hematology, Winship Cancer Institute, Emory University, Atlanta, Georgia 30322, USAEmail: Bryan D Shelby - bshelby@emory.edu; Heather L LaMarca - lamarca@bcm.edu;...
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Báo cáo hóa học: " Kaposi''''s sarcoma associated herpesvirus G-protein coupled receptor activation of cyclooxygenase-2 in vascular endothelial cells" ppt
... pcDNA3vector alone displayed minimal COX-2 promoter activityat each amount analyzed in these experiments. Activation of the cellular promoter should lead to increased mRNAsynthesis and this was the case. ... Sadagopan S, Sivakumar R, Veettil MV,Naranatt PP, Smith MM, Chandran B: Cyclooxygenase 2 inducedby Kaposi's sarcoma- associated herpesvirus early during in vitro infection of target cells plays ... expressionmay have a role in KSHV replication as well. The study bySharma-Walia et al suggests that COX-2 and PGE2 playroles in facilitating latent viral gene expression and the establishment and maintenance...
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Báo cáo y học: " GITR signaling potentiates airway hyperresponsiveness by enhancing Th2 cell activity in a mouse model of asthma" ppt
... as mean ± standard error of mean(s.e.m.). After log transformation, airway responsivenessto methacholine was statistically analyzed by a generallinear model of repeated measurements (ANOVA) ... number of regulatory T cells present in the lungs [5]. These data identify Treg cells as a potentially rel-evant target for therapeutic intervention in allergicasthma, in particular in case of ... characterized by airway hyperresponsiveness (AHR) and allergicinflammation of the airways, driven by allergen-specific Th2 cells. The asthma phenotypes and especiallyAHR are sensitive to the...
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Báo cáo Y học: Two GPX-like proteins from Lycopersicon esculentum and Helianthus annuus are antioxidant enzymes with phospholipid hydroperoxide glutathione peroxidase and thioredoxin peroxidase activities pptx
... insertion of a selenocysteine in mammalGPXs. The selenocysteine residue is important for the catalytic activity of GPX as replacement of selenocysteine bycysteine greatly reduces the activity of the ... respective apparentKmvalues. There was no detectable activity with hydrogenperoxide.Considering the replacement of the selenocysteine, one of the catalytic residues known to be critical for animal ... variations in the tissue and the subcellular concentrations of substratesand reducing substrates, dual catalytic activities for a givenenzyme might constitute an economical way plant cells haveevolved...
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Báo cáo y học: " Private specificities can dominate the humoral response to self-antigens in patients with cryptogenic fibrosing alveolitis " pps
... 35:821–830.16. Friedman AW, Targoff IN, Arnett FC: Interstitial lung disease with autoantibodies against aminoacyl-tRNA synthetases in the absence of clinically apparent myositis. Semin ArthritisRheum ... by standard dideoxy chain termination.Freckle assayClonal phage preparations were titrated and applied to a bacterial lawn using a plate replicator to achieve a plaquedensity of approximately ... evidence of antibodies to ATS, IGBP1 or the brainexpressed sequence tag (EST) in any of these sera. Con-vincingly, the index case retained a strong reaction to each of these antigens in sera obtained...
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Báo cáo y học: " Human immunodeficiency virus type 1 specific cytotoxic T lymphocyte responses in Chinese infected with HIV-1 B''''/C Recombinant (CRF07_BC)" pdf
... while Vpu and Tat are rarely targeted The immunodominance and cross-reactivity analysisFigure 2 The immunodominance and cross-reactivity analysis. The location of immunodominant and subdominant epitopes ... XGY, MA,participated in the design of the study and coordination.KLW participated in the data analysis and helped to draft the manuscript. BDW, YS conceived of the study, and par-ticipated in ... cells/mm3). All individualswere anti-retroviral therapy naive at the time of study andinfected with HIV- 1 CRF07_BC. The study was approvedby the institutional review board of National Center forAIDS/STD...
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Báo cáo y học: " Bench-to-bedside review: The gut as an endocrine organ in the critically ill" pdf
... patients with anorexia nervosa is associated with an increase in plasma CCK [57]. Accordingly, we anticipated that early, rather than delayed, enteral nutrition in the critically ill may attenuate ... both insulin and glucagon may attenuate the variability in glycaemia when using GLP-1 compared with insulin therapy. To date we have evaluated the eff ects of the synthetic peptide to establish ... Adam.Deane@adelaide.edu.au1Royal Adelaide Hospital, Department of Intensive Care, North Terrace, Adelaide, 5000 South AustraliaFull list of author information is available at the end of the...
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Báo cáo y học: " Functional markers to predict the need for prolonged mechanical ventilation in patients with Guillain-Barré syndrome" ppsx
... AbbreviationsGBS, Guillain-Barré syndrome; MV, mechanical ventilation; NIMV, non-invasive mechanical ventilation.Competing interests The authors declare that they have no competing interests.Published: ... Chevret S, Bourdain F, Raphaël JC; French Cooperative Group on Plasma Exchange in Guillain-Barré Syndrome: Early predictors of mechanical ventilation in Guillain-Barré syndrome. Crit Care Med 2003, ... tracheostomy as a determinant of weaning success in critically ill patients: a retrospective study. Crit Care 2005, 9:R46-52.8. Garpestad E, Brennan J, Hill NS: Noninvasive ventilation for critical care....
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