báo cáo khoa học: " Investigating the complementary value of discrete choice experiments for the evaluation of barriers and facilitators in implementation research: a questionnaire survey" pot

... conception and design of the study and planning of the work that led to the manuscript, the acquisition, and interpretation of data, and has been involved in drafting and critically revising the manuscript ... implementation of the guideline for breast cancer surgery in day care. The objec-tive of our study was to investigate the complementary value of DCE for the evaluation of barriers and facilitators in implementation ... citation purposes) Implementation ScienceOpen AccessResearch article Investigating the complementary value of discrete choice experiments for the evaluation of barriers and facilitators in implementation...

Báo cáo y học: "Investigating the complementary value of discrete choice experiments for the evaluation of barriers and facilitators in implementation research: a questionnaire survey" pptx

... onehand and facilitators on the other hand.Table 4: Health care professionals' perceptions about potential barriers and facilitators to the implementation of the guideline for breast cancer ... conception and design of the study and planning of the work that led to the manuscript, the acquisition, and interpretation of data, and has been involved in drafting and critically revising the manuscript ... was to investigate the complementary value of DCE for the evaluation of barriers and facilitators in implementation research. To meet this objective wecompared the results of a traditional questionnaire...

Tài liệu Báo cáo khoa học: What makes biochemical networks tick? A graphical tool for the identiﬁcation of oscillophores ppt

... values and a 3< 0 in the unstable steady state, oscillations can beobtained. Analysis of negative and positive subgraphs and comparison of their values gives rise to the estimation of the kinetic ... the kinetic parameters t hat enable such oscillations. The mainresult of such an analysis is that oscillations arise if t heparameter k3is the l argest and the parameters k6 and k7are the ... removal. It is obtained for allsubstrates of any elementary reaction. The main point of the present section is that any Jacobianmatrix element equals the sum of a number of direct parallel in uence...

Báo cáo khoa học: Afﬁnity puriﬁcation-mass spectrometry Powerful tools for the characterization of protein complexes ppt

... nuclearpre-mRNA and to catalyze the accurate removal of introns and ligation of exons to yield a mature mRNA. The afﬁnity of the splicing complexes to RNA was used in this approach for the isolation of the ... epitope tags (e.g. Myc, HA,Flag, KT3) have been used successfully in the past and antibodies against these tags are commercially available. The underlying advantage of the approach is the highdegree ... Thesecollisions result in cleavage of the peptide along the peptidebackbone and creates a set of fragments that differ in lengthby one amino acid each. The masses of the fragments canagain...

Báo cáo khoa học: Ionizing radiation utilizes c-Jun N-terminal kinase for ampliﬁcation of mitochondrial apoptotic cell death in human cervical cancer cells pptx

... co-immunoprecitation assays to analyze the association of FADD and caspase-8 in HeLa cells after radiationtreatment. As shown in Fig. 1C, interaction betweenFADD and caspase-8 was increased in cells treatedM ... frommitochondria, and apoptotic cell death. Radiation also induced transcrip-tional upregulation of Fas, caspase-8 activation, Bax and Bak activation, and phosphorylation and downregulation of Bcl-2. Inhibition ... anti-cytochrome c, anti-AIF and anti -a- tubulin serum. a- tubulin was used as a cytosolic marker protein. (C) Radiation induces apoptotic conformational changes of Bax and Bak after irradiation(10 Gy). Activity-related...

Báo cáo khoa học: "Automatic Story Segmentation using a Bayesian Decision Framework for Statistical Models of Lexical Chain Features" pdf

... probability of seeing a lexical chain start / end at a particular instance is independent of the starts / ends of other chains. As a result, the probability of seeing a sequence of chain starts at a ... scoring methods including single and combined lexical chain features. The baseline result is ob-tained using a scoring function based on the like-lihoods of seeing a chain start or end at a ... boundaries are taken into consideration and statistically modeled. 2 Experimental Setup Experiments are conducted using data from the TDT-2 Voice of America Mandarin broadcast. In particular,...

Báo cáo khoa học: "A Seed-driven Bottom-up Machine Learning Framework for Extracting Relations of Various Complexity" pdf

... example rules for the prize award domain. One of the target relations in the domain is about a person who obtains a special prize in a cer-tain area in a certain year, namely, a quaternary ... 1998) and Snowball (Agichtein and Gravano, 2000), because there is no gold-standard evaluation corpus available. We have adapted the evaluation method suggested by Agichtein and Gravano, i.e., ... relevant for the success of a seed-based bootstrapping approach to relation extraction. One of these is the arity of the relation. Another one is the locality of the relation instance in an average...

báo cáo khoa học: " Knowledge transfer & exchange through social networks: building foundations for a community of practice within tobacco control" potx

... only increases in potential impact when theseactors are supported in working in a transdisciplinarymanner [27]. The task is finding avenues that initiate and sustain collaborative activity among ... meeting and conducting the evaluation with this in mind. Bringingbackgrounds in public health, community psychology and evaluation (CN) and organizational behaviour and network research (TH), the authors ... contributionsBoth authors equally contributed to the conceptualization of the study, its execution, and the overall analysis of the data. CN took the lead in developing the narrative for the manuscript and the...

Báo cáo khoa học: Investigating the role of the invariant carboxylate residues E552 and E1197 in the catalytic activity of Abcb1a (mouse Mdr3) docx

... coordinates and activates the attackingwater molecule that cleaves the terminal phosphate of bound ATP. In the latter model, the IC is part of a catalytic dyad, along with the histidine residue of ... isalmost normal. By contrast, when the charge isremoved, as in the glutamine (length of the side chainmaintained) and asparagine (shorter side chain)mutants, then trapping in the absence of Vi nowoccurs ... explanation for the inactivation of the catalytic activity with augmentation of afﬁnity for ATPat NBD1 would be that this could maintain the NBDs in a closed dimer for longer, thus allowing the...

Tài liệu Báo cáo khoa học: High-afﬁnity ligand binding by wild-type/mutant heteromeric complexes of the mannose pptx

... a ﬂattened b-barrel [16]. Ligand binding experiments have mapped the Man-6-P bindingdomains mainly to repeats 3 and 9, wherein mutation of critical residues can reduce ligand afﬁnity [17], and such ... binding ligand independently. The tables indicate the amounts of the various cDNAs transfected into cells for each condition and apply to the data shown both above and below the table. Valuesrepresent ... format from the amino terminus to the carboxyl terminus, with repeats of the ectodomain shown asrectangles. The shaded rectangles indicate repeats 3 and 9, towhich the main determinants of Man-6-P...

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