... domain of integrins binds directly to ECM proteins, the cytoplas-mic tail is linked to the actin cytoskeleton via signallingand adapter proteins, such as focal adhesion kinase(FAK), vinculin, ... spectrallydistinguished within the cell. Therefore, the intein-mediated approach for simultaneous, in vivo, site-specific (N- andC-terminus) conjugation of Quantum Dots to multiple protein targets ... of 14RESEA R C H Open AccessSplit-Inteins for Simultaneous, site-specific conjugation of Quantum Dots to multiple protein targets In vivoAnna Charalambous†, Ioanna Antoniades†, Neophytos...