báo cáo khoa học: "Quantum dot-induced cell death involves Fas upregulation and lipid peroxidation in human neuroblastoma cells" pptx

... AccessResearchQuantum dot-induced cell death involves Fas upregulation and lipid peroxidation in human neuroblastoma cellsAngela O Choi1, Sung Ju Cho1,2, Julie Desbarats3, Jasmina Lovrić1 and Dusica ... numbersby inducing apoptosis, and is involved in T cell- mediatedcytotoxicity. It can also induce neuronal cell death [18-21]. Activation of Fas receptor by Fas ligand recruits the Fas- Associated Death ... induced cell death involving Fas, lipid peroxidation and mitochondrial impair-ment. Cells exposed to cadmium telluride quantum dots (unmodified and NAC-modified) induce ROS which causes Fas upregulation...

Báo cáo sinh học: "Effect of ethanol on innate antiviral pathways and HCV replication in human liver cells" doc

... hepatocytes.Materials and methodsCells and chemicals Human hepatoma Huh7 cells were grown in DMEM con-taining 10% FBS, 1× penicillin, streptomycin, fungizone,10mM L-glutamine, and 1× non-essential amino acids ... Jak-Statpathways in human liver cells. To begin to address these issues, we characterized the interactionof acute ethanol on Jak-Stat and MAPK pathways in Huh7 cells, HCV replicon cells lines, and primary human ... Ras-ERK, and phosphoinositol 3 kinase(PI3K) [36-40]. However, p38 kinase activity, which isimportant in IFN-α and IFN-γ induced transcription, isnot involved in IFN induced Stat1 serine phosphorylation[16,19]....

báo cáo hóa học:"Effect of ethanol on innate antiviral pathways and HCV replication in human liver cells" potx

... hepatocytes.Materials and methodsCells and chemicals Human hepatoma Huh7 cells were grown in DMEM con-taining 10% FBS, 1× penicillin, streptomycin, fungizone,10mM L-glutamine, and 1× non-essential amino acids ... Jak-Statpathways in human liver cells. To begin to address these issues, we characterized the interactionof acute ethanol on Jak-Stat and MAPK pathways in Huh7 cells, HCV replicon cells lines, and primary human ... dependentfashion, and this coincided with a dose-dependentincrease in total Stat1 protein, a known ISG. When cellswere treated with a single dose of 100 mM ethanol,increases in HCV NS3 and NS5A...

báo cáo khoa học: " All-trans retinoic acid inhibits KIT activity and induces apoptosis in gastrointestinal stromal tumor GIST-T1 cell line by affecting on the expression of survivin and Bax protein" pdf

... al.: All-trans retinoic acid inhibits KIT activity and induces apoptosis in gastrointestinal stromal tumor GIST-T1 cell line by affecting on the expression of survivin and Bax protein. Journalof ... AccessAll-trans retinoic acid inhibits KIT activity and induces apoptosis in gastrointestinal stromaltumor GIST-T1 cell line by affecting on theexpression of survivin and Bax proteinHoang Thanh ... Y:Green tea (-)-epigalocatechin-3-gallate inhibits KIT activity and causescaspase-dependent cell death in gastrointestinal stromal tumorincluding imatinib-resistant cells. Cancer Biol Ther2009,...

báo cáo khoa học: "Promising cytotoxic activity profile of fermented wheat germ extract (Avemar®) in human cancer cell lines" pot

... RPMI 1640 and Penicillin/Streptomycin were obtained from PAA,Pasching, Austria. F BS was purchased Biochrom AG,Berlin, Germany. Cell lines and cultureThe following human cancer cell lines were ... mainly significant synergy was observed for the com-binations of FWGE and 5-FU (6 out o f 8 cell lines) and to a lesser extend for irinotecan and oxaliplatin (2 outof 8 cell lines). Drug interaction ... contains two quinones, 2-methoxy benzoquinone and 2,6-dimethoxybenzquinonethat likely play a significant role in exerting several of itsbiological properties [2]. Preclinical in vitro and in...

Tài liệu Báo cáo khoa học: Modulation of oat arginine decarboxylase gene expression and genome organization in transgenic Trypanosoma cruzi epimastigotes docx

... con-taining DNA spots (5 lg each) corresponding to inter-nal fragments of ADC or cruzipain genes. The latter(used as a control) is a housekeeping gene that encodesthe main cysteine proteinase ... then infect the mammalian host cells and replicateintracellularly after transforming into amastigotes [1–4].Epimastigotes from different wild-type strains ofT. cruzi are able to grow continuously ... to a-amanitin of the transcription of argininedecarboxylase (ADC) and cruzipain genes in transformed Trypano-soma cruzi. Permeable parasites were preincubated at 0 °C for5 min in the absence...

Tài liệu Báo cáo khoa học: "Discriminative Lexicon Adaptation for Improved Character Accuracy – A New Direction in Chinese Language Modeling" pptx

... Mar.Pak-kwong Wong and Chorkin Chan. 1996. Chineseword segmentation based on maximum matching and word binding force. In Proceedings of the 16thInternational Conference on Computational Linguis-tic, ... be used in the construction.That is, beginning with only characters in the lexi-con and using the training data to alter the currentlexicon in each iteration. This is also an interestingdirection.ReferencesMaximilian ... objective point of view since SDR evalua-tion is inevitably effected by the selected queries.5 Conclusion and Future WorkCharacters together is an interesting and distinctlanguage unit for Chinese....

Báo cáo khoa học: A new approach for distinguishing cathepsin E and D activity in antigen-processing organelles pdf

... proteinase with a limited distribu-tion in certain cell types, including gastric epithelialcells [4], but is mainly present in cells of the immuneKeywordsantigen-presenting cells; cathepsin ... be involved in antigenprocessing by B cells [27,28] microglia [29] and murinedendritic cells [7].Several studies have determined the subcellularlocalization of CatE and CatD in different cell ... [Epstein–Barr virus(EBV)-transformed B -cell line] and HaCaT (immortal-ized human keratinocyte cell line). PCR products fromthe cell lines were analyzed by gel electrophoresis and found to contain...

Báo cáo khoa học: Differential post-translational modiﬁcation of CD63 molecules during maturation of human dendritic cells potx

... (IFN-c)(Pharmingen).Metabolic labeling and immunoprecipitationPrior to metabolic labeling, cells were cultured in RPMIwithout methionine and cysteine for 20 min. Cells werelabeled for the times indicated in the same ... mediumcontaining 0.1–0.2 mCiÆmL)1[35S]methionine/cysteine and 10% dialyzed fetal bovine serum. Cells were washed and chased in complete medium, supplemented with 2 mMmethionine and cysteine, ... proteins, including thelysosomal associated membrane proteins 1 and 2 (LAMP-1 Fig. 5. Subcellular localization of CD63 and LAMP molecules in immature and maturedendritic cells. Immature and...

Báo cáo khoa học: Lipins from plants are phosphatidate phosphatases that restore lipid synthesis in apah1Dmutant strain of Saccharomyces cerevisiae ppt

... fusion in yeast cells is in u-enced by oleic acid supplementation. Yeast pah1D cells expressingGFP-AtPAH1 and the ensuing mutants were cultivated for 16 h in induction medium containing 2% ... phospatidate (PA), yielding diacyl-glycerol (DAG) and inorganic phosphate [1–3]. In eukaryotic cells, PAP activity plays a central role in both lipid metabolism and intracellular signaling mechanisms[4,5]. ... con-served serine residue for the enzyme activity in human Lipin-2 and mouse Lipin-1 and Lipin-2 has beendescribed previously [9]. For example, a rare human mutation S734L in LIPIN-2 gene causes...

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