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Báo cáo y học: "A protocol for classifying normal- and flat-arched foot posture for research studies using clinical and radiographic measurements" pps

Báo cáo y học:

Báo cáo y học: "A protocol for classifying normal- and flat-arched foot posture for research studies using clinical and radiographic measurements" pps

... protocol for classifying normal- and flat-arched foot posture for research studies using clinical and radiographic measurementsGeorge S Murley*1,2, Hylton B Menz2 and Karl B Landorf1,2Address: ... decreases with flat-arched foot posture; angle B, C and D increase with flat-arched foot posture, compared to the normal- arched foot posture. Normal-arched foot Flat-arched foot AA B D ... http://www.jfootankleres.com/content/2/1/22Page 11 of 13(page number not for citation purposes)Screening protocol for normal- and flat-arched foot postureFigure 8Screening protocol for normal- and flat-arched...
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Báo cáo y học: " A Dietary Supplement Containing Standardized Phaseolus vulgaris Extract Influences Body Composition of Overweight Men and Women"

... in which body weight and body fat composi-tion of generally healthy, overweight human volun-teers were examined before and after a 30-day oral treatment with placebo or a test formula containing ... 46interfering with and/ or slowing the breakdown of complex carbohydrates, thereby reducing the diges-tive availability of carbohydrate-derived calories, at least early on, and/ or favorably influencing ... individual comply by maintaining the overall diet and taking one tablet before a meal rich in carbohydrates? After providing written in-formed consent, each volunteer was examined by a physician...
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Báo cáo y học: "A blind deconvolution approach to high-resolution mapping of transcription factor binding sites from ChIP-seq data" pps

... yielded good performance. We chose a bandwidth of30 for IP reads and a bandwidth of 300 for control reads. For enriched region i, we obtain four density functions,, , , , for the forward and reverse ... problem for each i by startingwith Ni = 1 and solving the minimization over ai and mi byrandom-restart gradient descent (see, for example, [33]).We then increment Ni and solve over ai and ... amotif closely resembling that previously identified byPark and co-workers [16]. Notably, four binding sitesoccur in two closely spaced pairs, and three occur in aclosely spaced triplet, and it...
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Báo cáo y học: " A comparative analysis of HIV drug resistance interpretation based on short reverse transcriptase sequences versus full sequences" pps

... EFV (Figure 3b).The analyses for subtype F1 (3TC, ABC and TDF) and subtype G (d4T) were inconclusive. This can beexplainedbythesmallersamplesizeforsubtypeF1(N= 7 45) and G (N = 560) as compared ... BCO,respectively [21].In this analysis virco®TYPE VPT4.3.00 was used, withthe clinical and biological cut-offs currently in use onthe virco®TYPE report [20]. The optimal sequencelength for virco®TYPE ... (NWO/WOTRO), underthe Netherlands African Partnership for Capacity Development and clinical Interventions against Poverty related Diseases (NACCAP) for the AffordableResistance Test for Africa (ART-A)...
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Báo cáo y học: "A cyclic-RGD-BioShuttle functionalized with TMZ by DARinv “Click Chemistry” targeted to αvβ3 integrin for therapy"

... individual and not just standardized plan of treatment for every single patient and all available therapy options should be used, such as immunothe-rapy, surgery or chemotherapy sensibly using cytos-tatic ... N-(2-Aminopropyl)-4-(6-(pyrimidine-2-yl)-1,2,4,5-tetrazine-3-yl)benzamide 4 4-(6-(Pyrimidine-2-yl)-1,4-dihydro-1,2,4,5-tetrazine-3-yl)benzoic acid (3) was prepared from 2-cyanopyrimidine 1 a nd 4 -cyano-ben zoic ac id 2 by reaction with hydrazine and then oxidized ... and also converted to the pIC50 scale (-l og IC 50) (Table 1). Multiparametric Flow Cytometry Analysis Cell size and granularity The use of the flow cytometry parameters for- ward (FSC) and...
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Báo cáo Y học: A model for recognition of polychlorinated dibenzo-p-dioxins by the aryl hydrocarbon receptor docx

Báo cáo Y học: A model for recognition of polychlorinated dibenzo-p-dioxins by the aryl hydrocarbon receptor docx

... binding. These are g lycines224 and 251 that substitute Phe96 a nd Val120 in PYP, and Phe98 and Leu127 in HERG [16]. For both FixL and PYP, structures are known for theinactive and active signaling ... Two forms of aryl hydrocarbon receptor type 2 in rainbowtrout (Oncorhync hus mykiss). Evidence for dierential expression and enhancer speci®city. J. Biol. Chem. 274, 15159±15166.22. Roy, N.K. ... Helices and b strands are represented as white and black b ars, respectively. Secondary structure assignment for FixL, PYP a nd HERG is derived from thePDB entries. Colouring sc heme for resid...
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Báo cáo Y học: A new high affinity binding site for suppressor of cytokine signaling-3 on the erythropoietin receptor potx

Báo cáo Y học: A new high affinity binding site for suppressor of cytokine signaling-3 on the erythropoietin receptor potx

... L93A and R94E with the peptidepY429pY431 (pYpY). (B) Precipitation of SOCS-3 WT or SOCS-3R94E with the peptides pY429pY431 (pYpY), pY429F431 (pYF) and F429pY431 (FpY).2522 M. Ho¨rtner et al. ... peptide binds in a way very similar topY429pY431 with the residues Y) 2, Y+ 3, Y+ 4 and Y+ 5building up hydrophobic contacts to the SOCS-3 SH2domain. Serine at position Y+ 1 forms a hydrogen bondwith ... phosphotyrosine motifs pY343,pY401 and pY429pY431 of the EPO-receptorWe and others have recently shown that SOCS-3 exerts itsinhibitory activity on IL-6 signaling by binding to phos-photyrosine...
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Báo cáo Y học: A critical motif for oligomerization and chaperone activity of bacterial a-heat shock proteins pot

Báo cáo Y học: A critical motif for oligomerization and chaperone activity of bacterial a-heat shock proteins pot

... determined bythe Bradford assay. All protein concentrations reported inthis study are expressed in terms of protomers.Chaperone activity assayChaperone activity was determined by the citrate synthase(CS) ... with aA-crystallin and Hsp27 [45] indicatethat the dimeric building block of many a-Hsp proteins isformed by interacting bstrands in the a-crystallin domain.Although this may also apply to the ... [13].RESULTSConstruction of HspH and HspF derivatives for structure-function studies In order to study the principles of a-Hsp assembly and therelation between complex formation and chaperone activity,we constructed...
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Báo cáo Y học: A new conceptual framework for enzyme catalysis Hydrogen tunneling coupled to enzyme dynamics in flavoprotein and quinoprotein enzymes docx

Báo cáo Y học: A new conceptual framework for enzyme catalysis Hydrogen tunneling coupled to enzyme dynamics in flavoprotein and quinoprotein enzymes docx

... the tryptophan tryptophyl-quinone (TTQ)-dependent amine oxidases methylaminedehydrogenase (MADH) and aromatic amine dehydroge-nase (AADH), and also the flavoenzymes trimethylaminedehydrogenase ... framework for enzyme catalysisHydrogen tunneling coupled to enzyme dynamics in flavoprotein and quinoproteinenzymesMichael J. Sutcliffe1,2 and Nigel S. Scrutton1Departments of1Biochemistry and 2Chemistry, ... genericapplicability of TST to enzyme catalysed reactions came in1999 from experimental studies on enzymes catalysing C–Hbond breakage. Our own studies with methylamine dehy-drogenase [13], and almost...
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báo cáo hóa học:

báo cáo hóa học: " A protocol for the emergency department management of acute undifferentiated febrile illness in India" potx

... collectedincluded day of fever at presentation, day of fever reso-lution, investigations performed, antimicrobial therapyreceived or not, and final diagnosis. Thirty-day follow-up was performed by phone ... either by t he protocol or asdeemed most appropriate by the evaluating physician.Under the protocol, if an eligible patient was stable and had had less than 3 days of fever, all investigations and ... that isinformed by local infectious epidemiology [2]. In thispilot study, investigations were or could have beenavoided in 75.2% of patients, and antimicrobial therapywas unnecessary for fever...
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