... inHbA1cPregnancyCategorymetformin 50 0, 850 , 1000 Y 0.48 1.0 – 2.0 Bmetformin SR 50 0, 750 Y 0.98 1.0 – 2.0 Bpioglitazone 15, 30, 45 N 5. 95 1 .5 Crosiglitazone 2, 4, 8 N 5. 99 1 .5 Cglyburide 1. 25, 2 .5, 5 Y 0.2 1.0 ... available in strengths of 50 0 mg, 850 mg, and 1,000 mg tablets, as extended release form instrengths of 50 0 mg, 750 mg, and 1,000 mg, and a liquid form with 50 0 mg of metformin per 5 mL. Therecommended ... oxide levels (55 ,56 ), 4) decrease inflammatory markers such TNF, C-reactive protein, soluble CD40 ligand, and plasmamonocyte chemoattractant protein-1 (MCP-1) (46,47 ,57 ,58 ), and 5) enhance fibrinolysis...