báo cáo khoa học: "Antisense oligodeoxynucleotides targeting ATM strengthen apoptosis of laryngeal squamous cell carcinoma grown in nude mice" docx

... of 8 apoptosis in hep-2 cell line. It is first reported with AS-ODNs of ATM strengthening radio-induced apoptosis of hep-2 cell line grown in nude mice. In conclusion, radiotherapy combined ... Feng et al.: Antisense oligodeoxynucleotides targeting ATM strengthen apoptosis of laryngeal squamous cell carcinoma grown in nude mice. Journal of Experimental & Clinical CancerResearch ... RESEARC H Open AccessAntisense oligodeoxynucleotides targeting ATM strengthen apoptosis of laryngeal squamous cell carcinoma grown in nude miceJun Feng1,4†, Jian Zou1†,LiLi2,...

báo cáo khoa học: "Sentinel lymph node biopsy for high-risk cutaneous squamous cell carcinoma: clinical experience and review of literature" ppsx

... (A) High-risk invasive perineal squamous cell carcinoma (B) Blue-stained inguinal sentinel lymph node.Figure 2 Wide excision of perineal squamous cell carcinoma: H&E staining at 2X (A) and ... regardless of SLN status.Keywords: sentinel lymph node, squamous cell carcinoma, cutaneous, stagingIntroductionCutaneous squamous cell carcinoma (SCC) is overall thesecond most common skin cancer ... cutaneous squamous cell carcinoma (SCC) is associated with an increased risk of metastases. The role of sentinel lymph node (SLN) biopsy in these patients remains unclear. To address this uncertainty,...

Báo cáo khoa học: "Prognostic factors for lymph node metastasis from advanced squamous cell carcinoma of the skin of the trunk and extremities" doc

... issue.Background Squamous cell carcinoma of the skin (SCCS) is one of themost common cancers around the word [1,2], with anincreasing incidence at a rapid rate among Caucasians in Europe, America ... teosc@usp.br; Natalia Martins Perpetuo - ftnatalia@gmail.com; Andre Lopes Carvalho - cyan@uol.com.br* Corresponding author AbstractBackground: Squamous cell carcinoma (SCC) of the skin of the trunk and ... 19.3Characteristics of lymph node metastasisAnatomic siteRight axilla 4 7.0Left axilla 7 12.3Right inguinal groin 4 7.0Left inguinal groin 7 12.3None 35 61.4Time of presentationInitial (N1)...

Tài liệu Báo cáo khoa học: "Can you summarize this? Identifying correlates of input difﬁculty for generic multi-document summarization" docx

... characteristic of highly non-cohesive inputs consisting of unrelated documents.Number of topic signature terms for the inputset. The idea of topic signature terms was intro-duced by Lin and Hovy (Lin ... the writing of a good summary more dif-ficult, or easier. Summary length and the char-acteristics of the input are such constraints in- fluencing the quality of a potential summary. In this paper ... evalua-tions. Finally, the presented results are clearly just abeginning in understanding of summarization diffi-culty. A more complete characterization of summa-rization input will be necessary in the...

Báo cáo khoa học: Oxidative stress induces a reversible ﬂux of cysteine from tissues to blood in vivo in the rat pptx

... oxidized in RBCs mainly to mixed disulfides with proteins (GSSP)and recovered  80% of its initial value within 2 h of the end of treatment (Fig. 3B). Cys levels decreasedduring the first part of the ... in regu-lating the kinetics of formation of c-glutamylcysteine (c-GluCys), the first step in GSH synthesis. Intracellular Cys may derive from diet, intra-cellular stores, or methionine (Met), ... Propargyl-glycine is an inhibitor of cystathionase, the enzymethat forms cysteine from cystathionine in the TSP; in this case, treatment should eliminate the supply of Cys derived from methionine [28]....

Báo cáo khoa học: Amino acid residues on the surface of soybean 4-kDa peptide involved in the interaction with its binding protein potx

... in maintaining the hairpin-b during interaction withsolvent.Interaction of insulin with the 43-kDa proteinSimilarly to the 4-kDa peptide, insulin is able to interactwith the 43-kDa protein ... consisting of Val23, Val29, Phe31 and Ile33 in the4-kDa peptide [8] is involved in binding to the 43-kDaprotein because of topochemical similarity to the activearea of insulin consisting of ValA3, ... described above, wereinvolved in binding to the 43-kDa protein. The substitution of Val12 and Arg18 to alanine aﬀected binding to the43-kDa protein. Unexpectedly, the side-chains of these tworesidues...

Báo cáo khoa học: Angiogenin prevents serum withdrawal-induced apoptosis of P19 embryonal carcinoma cells doc

... the cut-off value of propidium iodideand Annexin–FITC staining. (C) EB ⁄ AO staining. Cells were cultured in 10% fetal bovine serum or in serum-free medium in the absence orpresence of ANG for ... resuspended in 1 · Binding Buffer at a con-centration of 1 · 106cellsÆmL)1. An aliquot of 100 lL wasmixed with 5 lL of FITC–Annexin V and 5 lL of PI, andincubated at room temperature for 15 min in ... protectagainst cell death in non-neuronal cells induced by oxi-dative stress or calcium ﬂux [30,31]. In neuronal cells,Bcl-2 overexpression eliminates serum deprivation-induced cell death of brainstem...

Báo cáo khoa học: Quenched hydrogen ⁄deuterium exchange NMR characterization of amyloid-b peptide aggregates formed in the presence of Cu2+ or Zn2+ ppt

... 3A).The increased solvent accessibility of the turn regionwithin Zn2+-induced Ab(1–40) aggregates correlateswell with a proposed second weak binding site forZn2+involving Asp23–Lys28 in the ... by preincubating samples in D2O for 24 hbefore analysis. The length of incubation ensuresdetection of only those amide protons that are pro-tected as a result of hydrogen bonding within second-ary ... protec-tion. This is reasonable, as metal binding occurs withinthe ﬁrst 14 residues, inducing a low degree of second-ary structure [33,50]. However, the remaining parts of both Ab(1–40) and Ab(1–42) still...

Báo cáo khoa hoc:" Retroperitoneoscopic radical nephrectomy with a small incision for renal cell carcinoma: Comparison with the conventional method" docx

... forrenal cell ca rcinoma was introduced into our institution,we performed a combined small skin incision method in our hospital. That’s because we thought that the combinedsmall skin incision ... renal cell carci-noma soon after introducing it into their institutionwith the outcomes of an open laparoscopic partialnephrectomy for renal cell carcinoma, and reported thatthe incidence of intraoperative ... was 1 in 29.4%, 2 in 51%, 3 in 13 .7%, and in the latter, t hatgrade was 1 in 24.2%, 2 in 60.6%, 3 in 3%. In the A metho d group, complications were found in 4cases: a descending mesocolon injury...

Báo cáo khoa học: " Mass transfer, clearance and plasma concentration of procalcitonin during continuous venovenous hemofiltration in patients with septic shock and acute oliguric renal failure" ppsx

... the clini-cians to a new paradigm in a nonrenal indication and toadjunctive treatment of CVVH in sepsis, leading to more inter-est in cytokine removal [10]. Little is known about PCT in patients ... procalcitonin (PCT) in patients with septicshock during continuous venovenous hemofiltration (CVVH), and to assess the mechanisms of elimination of PCT.Setting The medical department of intensive ... procalcitonin; T0 = beginning of CVVH; T15′ = after 15 min of CVVH; T60′ = after60 min of CVVH; T6h = after 6 hours of CVVH.AbstractObjectives To measure the mass transfer and clearance of procalcitonin...

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