báo cáo khoa học: " Microarray-based analysis of microRNA expression in breast cancer stem cells" doc

... Access Microarray-based analysis of microRNA expression in breast cancer stem cellsJian-guo Sun1, Rong-xia Liao2, Jun Qiu1, Jun-yu Jin1, Xin-xin Wang1, Yu-zhong Duan1, Fang-lin Chen1, ... studying breast can cer-initiating cells and developing therapeutic strategies aimed at eradicating thetumorigenic subpopulation of cells in breast cancer. Background Breast cancer is one of the ... CellDeath 4 inhibits breast cancer cell invasion by increasing TissueInhibitor of Metalloproteinases-2 expression. Breast Cancer Res Treat 2009,114(2):203-209.37. Frankel LB, Christoffersen NR,...

Báo cáo y học: "Microarray analysis of microRNA expression in the developing mammalian brain" ppt

... the profile of microRNAs expressed in the developing mouse brain. We observed atemporal wave of expression of microRNAs, suggesting that microRNAs play important roles in the development of the ... cited.Microarray analysis of microRNA expression in the developing mammalian brain<p>MicroRNAs are a large new class of tiny regulatory RNAs found in nematodes, plants, insects and mammals. MicroRNAs ... data indicate that murine braindevelopment involves a wave of expression of sequentialclasses of microRNAs (Figure 3a).We also grouped the developmental time points according totheir microRNA...

Báo cáo khoa học: Mutational analysis of functional domains in Mrs2p, the mitochondrial Mg2+ channel protein of Saccharomyces cerevisiae ppt

... 7B and C). Effects of this deletion ongrowth of yeast cells were similar in strains containingmitochondrial group II introns and in strains lackingthese introns. Accordingly, the ARM deletion ... were in the range of those determined for multicopy expression of wild-type Mrs2p. In contrast, expression of Mrs2-HA-F2from a low-copy vector did not restore the rapid in ux of Mg2+into ... coiled-coil domains andadjacent conserved sequences either are involved in oligomerization of the Mrs2p channel protein or in forming structures participating in the gating of thischannel....

Báo cáo khoa học: Kinetic analysis of zymogen autoactivation in the presence of a reversible inhibitor pptx

... 3. Plot of k*catand K*magainst [I]0. (A) Effect of p-amindino-benzamidine concen tratio n on kÃcatfor autoactivation of trypsinogenby trypsin. (B) Effec t of p-amindinobenzamidine concentratio ... oncentrations of p-amindinobenzamidine.Figure 2B shows time courses for trypsinogen autoactiva-tion in the prese nce o f 100 lMp-amindinobenzamidine. Asseen in this figure, the presence of p-amindinobenzamidinelengthened ... grade. In kinetic studies of the autocatalytic conversion of trypsinogen into trypsin, aliquots of the incubation mixture of trypsinogen and trypsin were periodically removed andthe ac tivity of...

Báo cáo khoa học: Functional analysis of the methylmalonyl-CoA epimerase from Caenorhabditis elegans docx

... of the domains occurs in several differentways, suggesting that the evolution of these proteinsprobably involved multiple gene duplication, genefusion and domain swapping events. Members of ... activity was determined. Analysis of the protein expression pattern at both the tissue and subcellular level by microinjection of greenfluorescent protein constructs revealed expression in the pharynx, ... strongly inhibited GFP fluorescence(Fig. 8L,M).Tissue distribution of MCE in eukaryotes has notbeen investigated. However, expression profiles of pre-ceeding and succeeding enzymes of the pathway...

Báo cáo khoa học: "Computational Analysis of Move Structures in Academic Abstracts" docx

... tagging under different values of parameters. The parameters involved included the weight of transitional probability function, the number of sentences in an abstract, the minimal number of ... attention and become the mainstream of English for Specific Purposes, particularly in the field of English of Academic Writing (EAW). EAW deals mainly with genres, including research articles (RAs), ... of academic writing. RAs play the most important role of offering researchers the access to actively participating in the academic and discourse community and sharing academic research information...

Báo cáo khoa học: "Molecular analysis of hprt mutation in B6C3F1 mice exposed to ozone alone and combined treatment of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone and/or dibutyl phthalate for 32 and 52 weeks" ppsx

... [-]-1-methyl-2-[3-pyridyl]-pyrrolidine (nicotine)during maturation, air-curing, and storage of tobacco, aswell as during combustion of cigarettes [13,14]. NNKinduces lung tumors in rodents independent of the route of administration ... the source of total RNAfor RT-PCR reactions. For the initial RT-PCR amplification of hprt mRNA, 4µl of the cell lysate was used in a finalvolume of 20µl RT-PCR containing 2µl of 10×VM ... number in the parenthesis indicate percentage versus the number of total clones.Table 2. DNA sequence analysis of hprt mutant in splenic cells of B6C3F1 female mice in 52-wk studyType of mutationNumber...

Báo cáo khoa học: "Comparative analysis of heart functions in micropigs and conventional pigs using echocardiography and radiography" docx

... class="bi x0 y1 w1 h 2" alt ="" ...

Báo cáo khoa hoc:" Power analysis of QTL detection in half-sib families using selective DNA pooling" pptx

... squares interval mapping of QTLbased on selective DNA pooling, Proceedings of the 27th International Confer-ence on Animal Genetics ISAG2000, 22–26 July, University of Minneapolis,Minneapolis, Minnesota.To ... particulardrawback of DNA pooling estimation has been studied in detail in [11] and [17].Adequate choice of sires, attending to the degree of presence of their markeralleles within the population of dams, ... (Tab. III) that the effect of dominance was highly in uencedby allele frequencies in the population of dams. For a certain level of additiveeffect, the joint effect of dominance and marker allele...

báo cáo khoa học: "The analysis of quantitative variation in natural populations with isofemale strains" pptx

... graphed in figure 1.C. Isofemale strains maintained at a finite population sizeInbreeding will increase divergence among isofemale strains if they are maintainedat small ... strains using the inbree-ding coefficient F (FALCONER, 1981, p. 241) i.e.,Isofemale strains expanded to an infinite population size have an inbreeding coefficient of 1/4 ... was taken from the intersection of theanterior cross vein and longitudinal vein 3 (L3) to the intersection of L3 with the distalwing margin. Wing width was taken as...

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