Textbook of Neuroanaesthesia and Critical Care - part 10 ppt

... and sedation for adults and children in this 'unfriendly' and often isolated environment and it is now possible to safely monitor critically ill patients for MRI. The use of high-strength ... Group of Conference of Medical Royal Colleges and their Faculties in the United Kingdom. Diagnosis of death. BMJ 1976; ii: 1187–1188.8. Working Group of Conference of Medical Royal Colleges and ... support 5 mg/kg/minTable 27.13 Rule of 100 sSystolic blood pressure > ;100 mmHgUrine output > ;100 ml/hPaO2> ;100 mmHgHaemoglobin > ;100 g/lcontractility and to increase organ perfusion...

Textbook of Neuroanaesthesia and Critical Care - part 7 pptx

... adenoma of corticotrophic cells of the anterior pituitary.Physiologically, corticotrophin-releasing hormone (CRH) from the hypothalamus stimulates the synthesis and release of ACTH and other pro-opiomelanocortin ... sources.15,16Physical FindingsSymptoms and signs depend on the degree and duration of disease and are caused by:• endocrine effects of ACTH on cortisol, adrenal androgens and aldosterone, to a lesser ... disturbances in females and loss of libido in men, and to stimulation of the mammary gland, giving galactorrhoea (Table 18.2). Over half are microadenomas, sometimes occurring as part of the multiple...

Textbook of Neuroanaesthesia and Critical Care - part 8 pptx

... Perkins WJ, Karlsson BR et al. The effects of dizocilpine maleate (MK-801), an antagonist of the N-methyl-D-aspartate receptor, on neurologic recovery and histopathology following complete cerebral ... desflurane and propofol anesthesia. Anesthesiology 1995; 83: 66–76.80. Matta BF, Mayberg TS, Lam AM. Direct cerebrovascular effects of halothane, isoflurane and desflurane during propofol-induced ... Britain and Ireland. Recommendations for the transfer of patients with acute head injuries to neurosurgical units. AAGBI, London, 1996.75. Royal College of Surgeons of England. Report of the...

Textbook of Neuroanaesthesia and Critical Care - part 9 ppt

... patients.82Evidence for the Efficacy of Specific Monitoring and Management of Stroke Patients on Intensive Care There have been several small non-randomized studies of stroke intensive care units but to date, ... amplitudes.References1. Fink ME, Rowland LP. Respiratory care: diagnosis and management. In: Rowland LP (ed) Merritt's textbook of neurology, 9th edn. Williams and Wilkins, Baltimore, 1995; pp ... mortality and major morbidity results from all randomised trials of more than 100 0 patients. Lancet 1994; 343: 311–322.55. The National Institute of Neurological Disorders and Stroke rt-PA Stroke...

Textbook of Neuroanaesthesia and Critical Care - part 1 potx

... doses (3 mg/kg) of morphine and moderate doses of fentanyl (15 μg/kg) have little effect on CBF and CMR, high doses of fentanyl (50 100 μg/kg)89 and sufentanil90 depress CMR and CBF. Results ... aqueduct of Sylvius through the dorsal aspect of the midbrain to open out into the diamond-shaped fourth ventricle. This has the cerebellum as its roof and the dorsal aspect of the pons and medulla ... Neurophysiology Department of Clinical Neurophysiology Addenbrookes Hospital Cambridge, UKBasil F Matta MB BCh BA BOA DA FRCA Consultant in Anaesthesia and Neuro -Critical Care Director of Neuroanaesthetic...

Textbook of Neuroanaesthesia and Critical Care - part 2 ppsx

... out of 76 patients in one study of head-injured patients and 11 of the 18 died.39 Tindall et al40 showed that a transient rise in PaCO2 often preceded the development of an A wave and ... 1.5 MAC end-tidal concentrations of sevoflurane were compared with MAC-equivalent concentrations of enflurane and halothane, significant increases in ICP were found only with enflurane and halothane. ... deactivation of prostaglandin synthetase. J Biol Chem 1976; 257: 7329. 103 . Van Den Kerckhoff W, Hossman KA, Hossman V. No effect of prostacyclin on blood flow, regulation of blood flow and blood...

Textbook of Neuroanaesthesia and Critical Care - part 3 doc

... indicator respectively, Vb and Vi the volumes (ml) of blood and indicator, λb and λi the specific heat of blood and indicator, and ρb and ρi the density of blood and indicator.If time is ... in part at least, is due to the lack of non-invasive, easy-to-use, reliable equipment that can measure CBF with well-defined thresholds.However, the benefits of monitoring CBF in the brain-injured ... pulse-related inflow of the arterial blood can be compensated for by an equivalent outflow of the venous blood.25 Because of the different time profiles of arterial pulsatile inflow and the...

Textbook of Neuroanaesthesia and Critical Care - part 6 pps

... spinal surgery and craniofacial operations. Systolic blood pressures of 50 mmHg and above are well tolerated by children under the age of 10 and of 70 mmHg and above in children over 10. Techniques ... Evidence of cardiac disease should be sought by careful history and thorough examination, noting the presence of angina and its severity, previous myocardial infarction and symptoms and signs of ... in FV on cross-clamp application and the internal carotid artery associated change in HBdiff(ICA-ΔHbdiff). An ICA-ΔHbdiff>6.8 μmol/l was 100 % specific for SCI and ICA-ΔHBdiff<0.5...

Chapter 109. Disorders of Platelets and Vessel Wall (Part 10) pptx

... replaced. von Willebrand Disease: Treatment The mainstay of treatment for type 1 vWD is 1-deamino-8-D-arginine vasopressin (DDAVP, or desmopressin), which results in release of vWF and FVIII from ... using it. In patients who respond well (increase in values of two- to fourfold), it can be used for procedures with minor-to-moderate risk of bleeding. Depending on the procedure, additional doses ... Disorders of the Vessel Wall The vessel wall is an integral part of hemostasis, and separation of a fluid phase is artificial, particularly in disorders such as TTP or HIT that clearly involve...

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