Báo cáo y học: "Dating the age of admixture via wavelet transform analysis of genome-wide data " pptx
Báo cáo y học: "Dating the age of admixture via wavelet transform analysis of genome-wide data." pptx
... position. These wave frequencies are then usedas a measure of th e width of the ancestral blocks. Thereare several advantages to the wavelet transform approach. First, wavelet transform of the discrete ... analyze genome-wide admixture structure, and introduce wavelet transform analysis as a method for estimating the time of admixture. We test the wavelet transform method with simulations and apply ... from southern Africa. Nature 2010, 463:943-947.doi:10.1186/gb-2011-12-2-r19Cite this article as: Pugach et al.: Dating the age of admixture via wavelet transform analysis of genome-wide data. ...
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Báo cáo y học: " Stress response regulators identified through genome-wide transcriptome analysis of the (p) ppGpp-dependent response in Rhizobium " docx
... 12:R17http://genomebiology.com/2011/12/2/R17Page 6 of 19 of (p)ppGpp in E. coli. Of the many detect ed (p)ppGpptargets that may contribute to the observed stress phe-notypes of the rsh mutant, we performed a phenotypic analysis o ... previously[29], showing the rsh mutant to be (p)ppGpp-deficient.However,duetothesensitivityoftheassay,thepre-sence of trace amounts of (p)ppGpp in the rsh mutant,possibly resulting from the presence ... identified.Conclusions Analysis of growth phase-specific gene expression of the R. etli wild type and rsh mutant has provided insightinto the (p)ppGpp regulon of R. etli,providingthefirst genome-wide view of the...
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Báo cáo y học: " Foot and ankle surgery in Australia: a descriptive analysis of the Medicare Benefits Schedule database, 1997–2006" potx
... sex, age- group and calendar year), as the publicly accessible ver-sion of the MBS database we used does not allow for the extraction of individual-level data. For each category of procedures, the ... http://www.jfootankleres.com/content/1/1/10Page 7 of 10(page number not for citation purposes)Discussion The aim of this study was to explore the epidemiology andcosts of foot and ankle surgery in Australia using data rou-tinely ... specifically pertain to the foot, the incidence of foot surgery reported here is an underestimate. Finally, analysis of the database was restricted to descriptive statis-tics, as individual-level data...
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Báo cáo y học: "Demonstrating the benefit of medical emergency teams (MET) proves more difficult than anticipated"
... anticipated. These factors significantly reduced the power of the study. Based on their findings, the authors estimate that more than 100 hospitals would be needed to show the 30% difference they sought. ... goal of identifying and treating patients early in the course of their illness is preferable to waiting until more serious signs and symptoms have developed. Certainly, at the University of ... benefit for MET may take longer than the 6-month period of this study. Contamination of control hospitals also may have been an issue. Though they did not receive the study-based educational...
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Báo cáo y học: " Introducing the Critical Care Forum’s ongoing review of medical statistics"
... the management of patients have a sound grasp of at least the basics of statistical methods. Unfortunately, in practice this isoften not true, with many relying on distant memories of poorly ... regression; and analysis of survival data. Ideally the series will evolve to meet the needs of Critical Care readers,and you are encouraged to suggest additional topics that youwould like to ... presentationand summary of data. It is unlikely that the material covered bythis article will be entirely new to any reader but it is includedas a simple introduction to some of the ideas and philosophiesthat...
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Tài liệu Báo cáo Y học: Exploring the role of a glycine cluster in cold adaptation of an alkaline phosphatase pdf
... although the HGGG loop was acritical structural element for the catalytic efficiency of the enzyme, the cold adaptation of the enzyme could not beattributed to the presence of the Gly cluster ... explored the possibility of modifying the psychrophilic properties of an enzyme byintroducing, via mutagenesis, predictable flexibility changesto key active site residues of the psychrophilic alkalinephosphatase ... particularly attempted to investigate the functional importance of the Gly pair, located in the vicinity of the active site of the cold adapted enzyme and to study itspotential role in the establishment...
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Tài liệu Báo cáo Y học: Dissecting the effect of trifluoroethanol on ribonuclease A Subtle structural changes detected by nonspecific proteases ppt
... the content of secondary structure only after the disruption of the native tertiary structure of RNase A(Figs 2–4). Interestingly, the preservation of the tertiarystructure coincides with the ... hydro-chloride (GdnHCl), urea or elevated temperatures, theydestroy the tertiary structure of proteins which results in the loss of enzymatic activity. Regarding the secondary struc-ture of ... significantchanges of the spectroscopic properties of the enzyme couldbe detected. Therefore, the decrease of the proteolyticsusceptibility has to be attributed to a decreased (local)flexibility of the RNase...
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Báo cáo Y học: Monitoring the structural consequences of Phe12 fi D-Phe and Leu15 fi Aib substitution in human/rat corticotropin releasing hormone Implications for design of CRH antagonists pdf
... for the final family isgiven in Fig. S1. Fig. 3A shows the family of 40 structuresand Table 1 contains a summary of statistical data indica-ting the quality of the 40 models and the average ... active conformation of the hormone[38,40]. The changes engineered in the sequence of the peptide, either through the nature of the side chain of the new amino acids or through their non-native ... side-chainapproach the other Aib methyl group (Fig. 3B). The average distance between the vicinal Val18 and Aib15methylsismeasuredas3.206A˚in the mean structure, while the other methyl of Aib15 is...
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Báo cáo Y học: Modeling the three-dimensional structure of H+-ATPase of Neurospora crassa Proposal for a proton pathway from the analysis of internal cavities pptx
... initiated by the lysis of awater molecule in the cytoplasmic phosphorylation site,implying that the proton pathway would begin close to the phosphorylated aspartate (Asp378). The major steps o f the ... catalyticactivity proceed essentially by the same mechanism. Indeed,catalytic residues occupy the same position in the 3Dstructures of the two enzymes. In addition, the p redictedsecondary structures ... nelectrogenic way using energy from M gATP hydrolysisand its catalytic cycle is characterized by the formation of a covalent enzyme-aspartyl phosphate intermediate[2,3,42,43]. The 3D structures of PMA1_NEUCR...
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Báo cáo Y học: Reconstructing the replication complex of AcMNPV pdf
... with2 lg of the reporter plasmid pCAPCAT, and either 0.5 lg of each of the clones of the overlapping AcMNPV k libraryor 1.0 lg of each plasmid of the overlapping lef library asdescribed by Passarelli ... by insertion of PCR products into the BglIIand PspAI sites of plasmid phsp70HAHisVI+ containing the 5¢ terminal amino acid sequence RYPYDVPDYARA. The sequence YPYDVPDYA constitutes the haemaggluti-nin ... Results from other coprecipitation studies supported the yeast two-hybrid results with the exception of the weakinteraction observed between LEF-3 and IE1 with the yeasttwo-hybrid system (Table...
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Từ khóa: Nghiên cứu sự hình thành lớp bảo vệ và khả năng chống ăn mòn của thép bền thời tiết trong điều kiện khí hậu nhiệt đới việt namNghiên cứu tổ chức chạy tàu hàng cố định theo thời gian trên đường sắt việt namGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitNGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWAN SLIDEPhối hợp giữa phòng văn hóa và thông tin với phòng giáo dục và đào tạo trong việc tuyên truyền, giáo dục, vận động xây dựng nông thôn mới huyện thanh thủy, tỉnh phú thọPhát triển mạng lưới kinh doanh nước sạch tại công ty TNHH một thành viên kinh doanh nước sạch quảng ninhPhát triển du lịch bền vững trên cơ sở bảo vệ môi trường tự nhiên vịnh hạ longPhát hiện xâm nhập dựa trên thuật toán k meansNghiên cứu tổng hợp các oxit hỗn hợp kích thƣớc nanomet ce 0 75 zr0 25o2 , ce 0 5 zr0 5o2 và khảo sát hoạt tính quang xúc tác của chúngTìm hiểu công cụ đánh giá hệ thống đảm bảo an toàn hệ thống thông tinSở hữu ruộng đất và kinh tế nông nghiệp châu ôn (lạng sơn) nửa đầu thế kỷ XIXTổ chức và hoạt động của Phòng Tư pháp từ thực tiễn tỉnh Phú Thọ (Luận văn thạc sĩ)Quản lý nợ xấu tại Agribank chi nhánh huyện Phù Yên, tỉnh Sơn La (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtTrách nhiệm của người sử dụng lao động đối với lao động nữ theo pháp luật lao động Việt Nam từ thực tiễn các khu công nghiệp tại thành phố Hồ Chí Minh (Luận văn thạc sĩ)BÀI HOÀN CHỈNH TỔNG QUAN VỀ MẠNG XÃ HỘIChiến lược marketing tại ngân hàng Agribank chi nhánh Sài Gòn từ 2013-2015