... monofunctional and bifunctional DNA glycosylases. A bifunc-tional DNA glycosylase also possesses AP-lyase activity (whichmakes an incision at an abasic site). AP site, abasic site; APE,apurinic ⁄ apyrimidinic ... DNAin vitro than on undamaged DNA, identifying a candi-date enzyme that may be involved in the degradationof oxidatively damaged mtDNA. Finally, the mecha-nism of strand breaks in mtDNA after ... of X-rays and hydrogen peroxide.Biofizika 51, 692–697.83 Alam TI, Kanki T, Muta T, Ukaji K, Abe Y, Nakay-ama H, Takio K, Hamasaki N & Kang D (2003)Human mitochondrial DNA is packaged with...