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Báo cáo y học: "Joining forces in the quest for orthologs" ppsx

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Báo cáo y học: "Special considerations in the treatment of patients with bipolar disorder and medical co-morbidities"

... nutrient intake and physical activity. In assessing the nutrient intake of persons with bipolar disorder, Elmslie and colleagues found that they had increasedintake of carbohydrates and sweets, ... Pharmacotherapy and affective epi-sodes both influence appetite and physical activity,thereby increasing the risk for obesity. Obesity in bipolar patients is correlated with a greater number of lifetimedepressive ... with bipolar disorder are among the most chal-lenging to treat pharmacologically, especially in the pres-ence of medical comorbidity. Although the rates of medical comorbidity are high in patients...
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Báo cáo y học: "Genetic polymorphisms in the nucleotide excision repair pathway and lung cancer risk: A meta-analysis"

... Ivyspring International Publisher. All rights reserved Review Genetic polymorphisms in the nucleotide excision repair pathway and lung cancer risk: A meta-analysis Chikako Kiyohara1 and ... muta-tions and initiating carcinogenesis. The capacity to repair DNA damage induced by activated carcinogens appears to be one of the host factors that may influ-ence lung cancer risk. A critical ... NER and is involved in the DNA damage recognition process. Both RPA and XPA preferentially bind damaged DNA, and because RPA and XPA di-rectly interact in the absence of DNA, the RPA-XPA complex...
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Báo cáo Y học: Expression pattern in the antennae of a newly isolated lepidopteran Gq protein a subunit cDNA potx

Báo cáo Y học: Expression pattern in the antennae of a newly isolated lepidopteran Gq protein a subunit cDNA potx

... the protein coding domain. Sequence analysis of the 3Â end cDNA revealed that there is a polyadenylation signal upstream of the poly (A) .Analysis of the primary structure of M. brassicaeGqa The ... observed in Gqa-like proteins. In particular, the cysteine doublet at the N-terminal part probably serves as a site for post-translational attachment of a palmitoyl group (16-carbon,saturated fatty ... 2002 Expression pattern in the antennae of a newly isolated lepidopteran Gq protein a subunit cDNA Emmanuelle Jacquin-Joly1, Marie-Christine Francáois1, Michael Burnet2, Philippe Lucas1,Franck...
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Báo cáo y học: "Treating rhinitis in the older population: special considerations" pdf

... paid in the general medical literature. In the most recently pub-lished highly regarded geriatric text, rhinitis is notincluded in the index whereas rhinophyma is [1]. The number of Americans older ... purposes)Allergy, Asthma & Clinical ImmunologyOpen AccessReviewTreating rhinitis in the older population: special considerationsRaymond G SlavinAddress: Department of Internal Medicine, Division ... mucous-secretingglands; the effectiveness of the mucociliary system isreduced, resulting in symptoms of nasal stuffiness. In addition, a decrease in nasal blood flow leads to atrophyand drying of the...
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Báo cáo y học: "Physical anhedonia in the acute phase of schizophrenia" doc

... phys-ical anhedonia and psychopathological parameters in the acute phase of schizophrenia or between physical anhe-donia and motor side – effects induced by antipsychoticagents. The aim of the ... patients using the RPAS and the AIMS, the second using the PANSS and the EPSE and the third using the BARS. Information from the patient's his-tory, concerning social-demographic and clinical ... psychopathology symptoms ormotor side-effects induced by antipsychotic agents.Regarding the relationship of physical anhedonia andnegative symptoms the results are in line with those byLoas et...
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Báo cáo y học: "Tissue engineering in the rheumatic diseases" ppsx

... [12].Joint tissue engineering: clinical applications The first entry for the key word ‘tissue engineering , alsotermed ‘regenerative medicine’, in the National Center forBiotechnology Information ... [55].Cell sources for tissue engineering in rheumatic diseasesToday, autologous chondrocytes represent the only cell typeroutinely used for joint cartilage repair. In the future, autolo-gous or ... vigorous investigation.ReviewTissue engineering in the rheumatic diseasesJochen Ringe and Michael SittingerTissue Engineering Laboratory and Berlin-Brandenburg Center for Regenerative Therapies,...
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Báo cáo y học: "Chemokine receptors in the rheumatoid synovium: upregulation of CXCR" potx

... joints, and it results in the accumu-lation of leukocytes within the synovial tissue (ST) andsynovial fluid (SF). The inflammatory infiltrate consists pre-dominantly of B lymphocytes, T lymphocytes ... recruitment of these cells into the RA synovium, in addition to their positioning and retention within the syno-vial infiltrates. In this regard, the role of CXCR5 on B cells in secondary lymphoid ... probablyresponsible for the increased expression of the receptor in this chronically inflamed tissue. The majority (seven out of eight) of the RA synovia included in this study containedsubstantial lymphoid...
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Báo cáo y học: "Somatic mutations in the mitochondria of rheumatoid arthritis synoviocytes" ppt

... monocytes may also be contributing to the pathol-ogy of other inflammatory autoimmune diseases. Such acorollary suggests it may be of interest to investigate mtDNAwithin other inflammatory autoimmune ... fibroblast lines. YM participated in the molecular genetic studies and analysis. EK procured the sam-ples and helped in the analysis of data. GW participated in the design of the study, analysis of data, ... type and earlybacterial infection in the joint. Somatic mutations in mitochondrial peptides displayed by MHCs may be recognizedas non-self, furthering the destructive immune infiltration of...
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Báo cáo y học: "Psychosocial aspects in the management of arthritis pain" pot

... depressive symptoms,even more so than activity losses in other domains [22]. The role of leisure in maintaining or restoring psychological well-being in the presence of arthritis pain warrants furtherstudy.Psychosocial ... Acomparison of conventional pain coping skills training andpain coping skills training with a maintenance training com-ponent: A daily diary analysis of short- and long-term treat-ment effects. J Pain ... way theymanage these aspects of their illness influences their abilityto engage in meaningful, obligatory and discretionaryactivities, including the domains of work, family life, leisure,and...
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Báo cáo y học: " Immune mechanisms in the pathogenesis of idiopathic inflammatory myopathies" doc

... immunohistochemical localization of inflammatory cells in idiopathic inflammatory myopathiesReference Polymyositis Dermatomyositis Inclusion-body myositisT lymphocytes[9] 53 patients. T lymphocytes were least ... concerning the role of T lymphocytes, B lymphocytes, dendritic cells, andother antigen-presenting cells (APCs) in the pathophysiology of IIMs.T lymphocytesT lymphocyte functionT lymphocytes ... findings concerning the role of T lymphocytes, B lymphocytes, dendritic cells, and other antigen-presenting cells in the pathophysiology of IIMs.Introduction Idiopathic inflammatory myopathies (IIMs)...
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Báo cáo y học:

Báo cáo y học: "Current approaches in the treatment of arthritic pain" pps

... beconfined to the periphery. The finding of increased areas of punctate hyperalgesia in patients with RA after topicalapplication of capsaicin is in accord with increasedexcitability of spinal ... role in the treatment of chronic pain, although there have been few studies assessing the efficacy of the technique for arthritic pain. Underlyingmechanisms of action remain unclear, but in studies ... also likely to influence activity. The multiplicity of mediators involved provides an opportunity for therapeuticintervention, and many of the commonly used therapeuticstrategies including acupuncture,...
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Báo cáo y học: "Recent developments in the immunobiology of rheumatoid arthritis" potx

... Beer Y: Interleukin-17 enhances tumor necro-sis factor alpha-induced synthesis of interleukins 1,6, and 8 in skin and synovial fibroblasts: a possible role as a ‘fine-tuningcytokine’ in inflammation ... anti-IL-15 therapy in RA patients [29].T helper 17 cellsThere is increasing evidence that IL-17 plays a role in the immunopathology of RA. This proinflammatory cytokine isproduced by T helper ... anti-CD20 antibody[2], and the increased interest in the role of autoantibodies in RA. In addition to producing antibodies, proinflammatorycytokines and chemokines, B cells efficiently act as antigen-presenting...
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Báo cáo y học: "A polymorphism in the human serotonin 5-HT2A receptor gene may protect against systemic sclerosis by reducing platelet aggregation" potx

... corre-sponding gene, is functionally relevant to platelet aggregation in vitro, dampening the responses to the serotoninergic stim-ulus. The functional relevance of this polymorphism may explain the inverse ... 1 Platelet aggregation induced by ADP and serotoninPlatelet aggregation induced by ADP and serotonin. Left panel: aggregation induced by 1 μM ADP + 1 μM buffer solution (plain Tyrode's solution ... is, in other diseases where the serotoninergic system is involved.ConclusionWe provide evidence that the His452Tyr substitution of the 5-HT2A receptor, determined by the C+1354T SNP of the...
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Báo cáo y học:

Báo cáo y học: "Joining forces in the quest for orthologs" ppsx

... organized the Quest for Orthologs’ meeting at the Wellcome Trust Conference Centre in Hinxton, UK in July 2009, to jointly address these issues by bringing together for the first time key representatives ... for their gene of interest. Furthermore, the absence of standardized benchmarks and formats makes the inte-gration or comparison of these different orthology datasets extremely challenging ... distinguishing orthologs from paralogs are outweighed by the risks of inference errors. Teresa Przytycka (National Center for Biotechnology Information, Bethesda, USA) and Ken Wolfe (Smurfit Institute...
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Báo cáo y học: " Membrane traffic in the post-genomic era." potx

... accumulating evi dence for regulation in the converse direction - of the membrane machinery by signaling - at multiple stages of both the membrane- biosynthetic and endocytic pathways [7,8].Analysis ... endocytic pathways in mammalian cellse main new advance introduced in the study of Collinet et al. is automated phenotyping of the endocytic pathway, using quantitative fluorescence microscopy. ... led to the identification of a variety of essential proteins mediating membrane traffic in the biosynthetic pathway of yeast, many of which have orthologs in mammals [3,4].A long-standing barrier...
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