... double-blind, randomised,
placebo-controlled study. Lancet 2000; 356 :52 9–34.
200. Mullis-Jansson SL et al. A randomized double-blind study of the effect of triiodothyronine on cardiac func-
tion ... EFFECT OF DIURESIS
DRUG DOSAGE FORMS (MG/DAY)
b
DOSAGE (MG) (HR) (HR)
Methyclothiazide Tab 2 .5, 5 mg. 2 .5 10 5 6 24
Aquatensen
Enduron
Various
Metolazone
d
Tab (Mykrox)
e
0 .5 mg...
... ed. Handbook of non-
prescription drugs. 10th ed. Washington, DC: American Pharmaceutical Association; 1993:89–1 15.
75. American Academy of Pediatrics. Committee on Drugs. Use of codeine- and ... 1–2 days.
57 ,58
D
RUG
-I
NDUCED
N
EPHROTOXICITY
8 45
(continued )
ch11.qxd 8/13/2001 2 :55 PM Page 8 45
Amiodarone
Mild increases in transaminases and LDH levels occur in up to one-ha...
... and 50 ,000/L, respectively. Then readminister at 100% of
dosage if nadir ANC was 1000– 150 0/L and/or PC was 50 ,000– 150 ,000/L;
75% of dosage if nadir ANC was 50 0/L and/or PC was 25, 000 50 ,000/L; ...
CLEARANCE OF DOSAGE
(ML/MIN) RECOMMENDED
> ;50 60–100 (0–40% reduction)
10 50 30 50 (50 –70% reduction)
<10 15 ( 85% reduction)
Dosage Forms. Tab 2 .5 mg; Inj (as sod...
... serotonin-receptor antagonist. Ann Pharmacother 19 95; 29:
1240 51 .
87. Freeman AJ et al. Selectivity of 5- HT
3
receptor antagonists and anti-emetic mechanisms of action. Anticancer
Drugs 1992;3:79– 85.
88. ... about 50 % of the total body clearance of
eptifibatide. Cl is 0. 055 –0. 058 L/kg/hr.
t
¹⁄₂
. 1 .5 2 .5 hr.
1
Adverse Reactions. Bleeding, particularly from vascular acce...