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Báo cáo y học: "Association of MICA with rheumatoid arthritis independent of known HLA-DRB1 risk alleles in a family-based and a case control study" pps

Báo cáo y học:

Báo cáo y học: "Association of MICA with rheumatoid arthritis independent of known HLA-DRB1 risk alleles in a family-based and a case control study" pps

... ligands in rheumatoid arthritis. Proc Natl Acad SciUSA 2003, 100:9452-9457.13. Kochi Y, Yamada R, Kobayashi K, Takahashi A, Suzuki A, Sekine A, Mabuchi A, Akiyama F, Tsunoda T, Nakamura Y, Yamamoto ... aim was to investigate the role of DNA polymorphisms of MICA in French Caucasian RA family trios and in a GermanCaucasian case- control cohort. Confounding by HLA-DRB1 risk alleles was controlled ... is associated with RA independent of known HLA-DRB1 risk alleles (Table 1c).Association of MICA- 250 with RA was stronger compared with association of other analyzed single markers (Table 1)and...
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Báo cáo y học: "Pooled indices to measure rheumatoid arthritis activity: a good reflection of the physician’s mind" pdf

... Disease Activity Index (SDAI), and the Clinical Disease Activity Index (CDAI). These indicesare essentially based on the same attributes of RA: jointcounts, the patient’s evaluation of RA activity, ... Musculoskeletal, and Skin Diseases, National Institutes of Health, Bethesda, Maryland, USACorresponding author: Daniel Aletaha, aletahad@mail.nih.govPublished: 14 December 2005 Arthritis Research & ... tohave less active disease? In a recent issue of Arthritis Research & Therapy, VanderCruyssen and colleagues [2] aimed to compare this aspect of validity for the various disease activity indices....
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Báo cáo y học: "Gitelman’s syndrome with persistent hypokalemia - don’t forget licorice, alcohol, lemon juice, iced tea and salt depletion: a case report" ppsx

... tea and low salt intake can further aggravate hypo -kalemia and provoke clinical symptoms. Case presentation A 31-year-old, previously healthy Caucasian Swiss manwas admitted to our hospital ... clinical symptoms. Finally, vomiting and failure to replace salt led to volume depletion and hypokalemiccrisis, with a plasma potassium level of 1.0 mmol/L and paralysis with respiratory failure ... corresponds to an intake of 60 to 90 mg/day of glycyrrhizinic acid.The patient was initially treated with parenteral and enteral potassium, spironolactone und indomethacin.Within 24 hours, his potassium...
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Báo cáo y học: " Autologous chondrocyte implantation for rheumatoid arthritis of the knee: a case report" pps

... joint pain. Plain radiographs (Figure 1a) revealed progression of arthritis with lateral joint spacenarrowing when compared with radiographs obtained4 years previously. The patient refused total ... (RA) is an autoimmune disease thatcauses chronic inflammat ion of the joints. To date,pharmacologic treatment remains the primary form of treatment, however, if pain and limitation of jointfunction ... woman with a painful,arthritic knee and her treatment using autologous chon-drocyte implantation (ACI). Case presentation A 35-year-old Korean woman with RA was admitted forrigh t kne e joint...
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Báo cáo Y học: The plant S-adenosyl-L-methionine:Mg-protoporphyrin IX methyltransferase is located in both envelope and thylakoid chloroplast membranes pot

Báo cáo Y học: The plant S-adenosyl-L-methionine:Mg-protoporphyrin IX methyltransferase is located in both envelope and thylakoid chloroplast membranes pot

... Nakayama, M., Masuda, T ., Bando, T., Yamagata, H., Ohta, H.& T akamiya, K. (1998) Cloning and expression of the s oybeanchlH gene encoding a s ubunit of Mg-chelatase an d localization of the ... hylakoids f ractions. The fractionswere analyzed by SDS/PAGE and C oomassie blue staining and MgPIXMT activity was compared to MGDG synthase activity a s a marker o fenvelope me mbranes and ... butpresumably involved in heme synthesis [4] and POR canassociate with the thylakoids [9]. Finally, the ®nal steps of chlorophyll synthesis, such as addition and r eduction of geranylgeranyl chain, are...
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Báo cáo y học: "Endogenous TGF-β activation by reactive oxygen species is key to Foxp3 induction in TCR-stimulated and HIV-1-infected human CD4+CD25- T cells" docx

... 5'-CAG-CAC-ATT-CCC-AGA-GTT-CCT-C-3' and 5'-GCG-TGT-GAA-CCA-GTG-GTA-GAT-C-3', and theFoxp3 probe was 5'-FAM-TCC-AGA-GAA-GCA-GCG-GAC-ACT-CAA-TG-TAMRA. Pre-developed Taqman ... USA and 2National Center for Biodefense and Infectious Diseases, Department of Molecular and Microbiology, George Mason University, Manassas, VA 20110, USAEmail: Shoba Amarnath - samarnath@mail.nih.gov; ... protein was determined by FACS staining. A. A representative overlay of histograms of ROS in the cultured T cells with (+MnTBAP) and without (-MnTBAP) MnTBAP at days 3 and 5. The filled histograms...
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Báo cáo y học: "Association of the T+294C polymorphism in PPAR δ with low HDL cholesterol and coronary heart disease risk in women"

... records and/ or self-reported questionnaire and each case was validated by cardiac ultrasound and/ or electrocardiographic examinations or by coronary angiography. Table 1: Patient characteristics. ... Genotyping DNA was extracted from white blood cells using standard methods. A mutagenically separated polymerase chain reaction (MS-PCR) was developed to separate wildtype (wt) and mutated alleles ... precipitation of apoB containing lipoproteins with phosphotungstate (Boehringer Mannheim). Apoliprotein AI (Apo AI) and Apo B were measured using the Beckmann Array 360 (Beckmann Instruments). Genotyping...
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Báo cáo Y học:Association of the thyrotropin receptor with calnexin, calreticulin and BiP Effects on the maturation of the receptor docx

Báo cáo Y học:Association of the thyrotropin receptor with calnexin, calreticulin and BiP Effects on the maturation of the receptor docx

... g.Immunoprecipitation and electrophoresisThe radiolabeled supernatant obtained was saved and incubated for 1 h at 4 °C with protein A- Sepharose and centrifuged for 2 min at 10 000 g. The supernatant wasincubated ... orCRT and the glycoprotein substrate. At the end of thepulse and at each chase time, cells were lysed and immunoprecipitation was carried out using mAb A1 0.The data obtained indicate that CST ... These data suggest that BiPhas a negative effect on the folding of TSHR. Theinteraction of this receptor with BiP leads to an increase in the degradation of TSHR and also to a decrease in theamount...
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Báo cáo Y học: Association of human tumor necrosis factor-related apoptosis inducing ligand with membrane upon acidification pdf

Báo cáo Y học: Association of human tumor necrosis factor-related apoptosis inducing ligand with membrane upon acidification pdf

... 1343–1354.7. Kayagaki, N., Yamaguchi, N., Nakayama, M., Kawasaki, A. ,Akiba,H.,Okuma,K.&Yagita,H.(1999)InvolvementofTNF-related apoptosis-inducing ligand in human CD4+T cell-mediated cytotoxicity. ... observations, structuralchanges of TRAIL induced by acidification reveal thatTRAIL might have a potential acid-enhanced cytotoxicity and its intrinsic property be also shared by those of TNF -a and ... and PtdSer at acidic pH values. In many cases, the binding of a protein with lipid bilayer disrupts the bilayer integrity tomake the membranes permeable [30,31]. To ascertainwhether TRAIL alters...
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Báo cáo y học: "Association of Adiposity, Cardiorespiratory Fitness and Exercise Practice with the Prevalence of Type 2 Diabetes in Brazilian Elderly Women" pot

... [3]. Weinstein et al [11] also found that general adiposity and physical activity are independent predictors of the prevalence of T2D. The combined analysis using BMI and “active” or “inactive” ... triglycerides and C-reactive protein, lower levels of HDL, silent myocardial ischemia, neuropathy, peripheral arterial insufficiency, myocardial infraction, macrovascular disease, abnormal myocardial ... prevent diabetes in managed care and community setting [1, 22, 29]. Health professionals should encourage individuals of all ages to maintain an active life-style that can attenuate the negative...
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