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Báo cáo y học: "Serum levels of biomarkers of bone and cartilage destruction and new bone formation in different cohorts of patients with axial spondyloarthritis with and without tumor necrosis factor-alpha blocker treatment" ppt

Báo cáo y học:

Báo cáo y học: "Serum levels of biomarkers of bone and cartilage destruction and new bone formation in different cohorts of patients with axial spondyloarthritis with and without tumor necrosis factor-alpha blocker treatment" ppt

... cartilage destruction and new bone formation in different cohorts of patients with axial spondyloarthritis with and without tumor necrosis factor-alpha blocker treatmentHeiner Appel1, Louise ... neoangiogenesis, and new bone formation in different cohorts of patients with axial spondyloarthritis with and without treatment with TNF-α blocker agents.Method TNF-α blocker- naïve AS patients were investigated ... (MMP-3), and bone- specific alkaline phosphatase (BALP) at base-line and after 1 and 2 years in a tumor necrosis factor-alpha blocker- naïve cohort of ankylosing spondylitis patientsMean serum levels of...
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Báo cáo y học: "Serum levels of autoantibodies against monomeric C-reactive protein are correlated with disease activity in systemic lupus erythematosus" potx

... consumption of CRP by ICs [35]. With this in mind we find the high fre-quency (4 of 4) of anti-CRP in patients with ongoingkidney involvement interesting, given the pathogeneticimplications of ICs in ... con-nection, and in view of earlier findings of mCRPexpression on human peripheral blood lymphocytes[38,39] and accelerated apoptosis of lymphocytes fromSLE patients [7], we find the inverse relation ... considerednegative. Six of 10 patients were anti-CRP positive at flare. Patients with active kidney involvement at the present flare are indicated byfilled circles, patients without kidney involvement by open...
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Báo cáo y học: " Serum levels of hyaluronic acid and chondroitin sulfate as a non-invasive method to evaluate healing after cartilage repair procedures" pptx

... progress in recent years. Certain cartilage- specific techniques such asdelayed gadolinium-enhanced MRI of cartilage (dGEMRIC) and T1-rho and T2-mapping have promise to assess tissuequality by indirectly ... antibodies and enzyme-linked immuno-sorbent assay to quantify serum levels of CS and HA,respectively, in a dog model. They followed two groupstreated with either SD or autologous chondrocytes (ACs) ... encountered in over 60% of knee arthroscopies [2]. While the natural history and pathophysiology of cartilage defects remain controver-sial, a significant number of patients present with symptomsthat...
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Báo cáo y học:

Báo cáo y học: "Serum levels of matrix metalloproteinases -1,-2,-3 and -9 in thoracic aortic diseases and acute myocardial ischemia" potx

... a large fam-ily of proteolytic enzymes containing a metal in theirorganic structure playing key roles in degradation of pro-teins in extracellular matrix and in tissue remodelingthrough complicated ... aorticaneurysm and group D included 13 patients with acutecoronary syndrome presenting with electrocardiographicchanges indicative of myocardial ischemia with or with- out elevation of myocardial enzymes. ... levels of MMP-3 in atheroscleroticplaques in any kind of aortic aneurysm [15,19,20]. High levels of MMP-3 have also been reported in the bloodserum of patients with coronary arteries aneurysm...
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Báo cáo y học:

Báo cáo y học: "Serum cystatin C levels to predict serum concentration of digoxin in Japanese patients

... digoxin in Japanese patients. The serum levels of Cys-C and Cr in the patients were higher than those in the healthy elderly subjects, but the increase of Cys-C was more predominant in the patients, ... participated in this study. The serum levels of Cys-C and Cr in the patients were higher than those in the healthy elderly subjects, but the increase of Cys-C was more predominant in the patients. ... concentrations of digoxin. Key words: Cystatin C, Creatinine, Digoxin, Serum concentration, Heart failure, Renal clearance 1. Introduction Cystatin C (Cys-C) is a non-glycosylated cationic protein of...
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Báo cáo y học: "Serum cathepsin K levels of patients with longstanding rheumatoid arthritis: correlation with radiological destruction" pptx

... to measure serum levels of cathe-psin K in RA and to prove that cathepsin K is a parameter of bone remodelling and resorption in a nonselected cohort of patients with longstanding RA. This patient ... cited.AbstractCathepsin K is a cysteine protease that plays an essential role in osteoclast function and in the degradation of proteincomponents of the bone matrix by cleaving proteins such ascollagen type ... arthritisIntroductionProgressive bone and cartilage destruction in arthritic jointsleads to irreversible joint destruction, and subsequently tofunctional declines and work disability [1,2]. New biomark-ers such as cartilage...
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Báo cáo sinh học:

Báo cáo sinh học: " Serum levels of preS antigen (HBpreSAg) in chronic hepatitis B virus infected patients" potx

... proteinanti-HBsanti-preS45.0kDa35.0kDa25.0kDaComparison of the binding ability of preS and preS1 to anti-preS by ELISA testFigure 2Comparison of the binding ability of preS and preS1 to anti-preS by ELISA test. Different amounts of recombinant ... Gu1, Ming Luo1,3 and Xiaofeng Zheng*1,2Address: 1National Laboratory of Protein Engineering and Plant Genetic Engineering, Peking University, Beijing, 100871, China, 2Department of Biochemistry ... DNA-containing Dane HBV particles, detection of HBpreSAgpresent in serum of HBV patients may have a clinical value in management of HBV infection. In previous reports,radioimmunoassays using monoclonal...
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Báo cáo y học:

Báo cáo y học: "Decreased levels of soluble amyloid β-protein precursor and β-amyloid protein in cerebrospinal fluid of patients with systemic lupus erythematosus" ppsx

... of the present study was to measure the levels of brain-specific proteins directly or indirectly related todementia disorders (tau, Aβ42, APP and TGF-β) in theCSF of SLE patients with and without ... CSFcontent of amyloid precursor protein (APP) in patients with SLE with and without CNS engagement, as well as in cerebrally healthy controlsubjects. (c) CSF content of tau in patients with SLE ... well as of lupus patients without MRI-verified brain pathology. Thisfinding, together with increased intrathecal levels of TGF-β, indicates an ongoing destructive parenchymatousprocess in the...
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Báo cáo y học: "Serum, urinary, and salivary nitric oxide in rheumatoid arthritis: complexities of interpreting nitric oxide measures" doc

... for individual differences in creatinine clearances. Thefinding of increased NOx and NOx/creatinine ratios in serum(but not in urine) in patients with RA raised the possibility thatcontrols and ... higheraverage urinary nitrate/creatinine ratio in patients with RA than in controls after only an overnight fast. Our analyses showedthat urinary NOx and NOx/creatinine levels after 1, 2, or 3 days of a ... described in patients with RA and in those with Sjögren's syndrome [52,53].Exocrine dysfunction of the lacrimal and salivary glands mayoccur in RA, leading in some cases to secondary Sjögren'ssyndrome...
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