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Báo cáo y học: "Chordin knockdown enhances the osteogenic differentiation of human mesenchymal stem cells" pdf

Báo cáo y học:

Báo cáo y học: "Chordin knockdown enhances the osteogenic differentiation of human mesenchymal stem cells" pdf

... follows: the BMP inhibitor chordin is produced endogenously during the osteogenic differentiation of human mesenchymal stem cells(MSCs); and blockade of the activity of the BMP inhibitorincreases the ... of chordin knockdown on the expression of markers of osteogenic differentiation in human MSCsEffect of chordin knockdown on the expression of markers of osteogenic differentiation in human MSCs. ... cellsFigure 1Response of human MSCs to osteogenic mediumResponse of human MSCs to osteogenic medium. Induction of an osteogenic phenotype of mesenchymal stem cells (MSCs) cultured in osteogenic media...
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Báo cáo Y học: Rapid caspase-dependent cell death in cultured human breast cancer cells induced by the polyamine analogue N1,N11-diethylnorspermine pdf

Báo cáo Y học: Rapid caspase-dependent cell death in cultured human breast cancer cells induced by the polyamine analogue N1,N11-diethylnorspermine pdf

... polyamines by downregulating the activity of the biosynthetic e nzymes and upregulating the activity of the catabolic enzyme spermidine/spermine N1-acetyltrans-ferase (SSAT) [8]. The effect of ... cellular pools of putres-cine, spermidine and spermine by down-regulating the activity of the polyamine biosynthetic enzymes a nd up-regu-lating the activity of the catabolic enzyme spermidine/spermine ... alone is that they usually fail todeplete the cells of all three polyamines. Subsequently,polyamine analogues have been synthesized and some of them have been shown to efficiently d eplete all...
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Báo cáo khoa học: Protein dissection enhances the amyloidogenic properties of a-lactalbumin potx

Báo cáo khoa học: Protein dissection enhances the amyloidogenic properties of a-lactalbumin potx

... in the aggregated mixture of intact LA and that the intensity of the CD signal of the helical structure ismuch higher than that of other secondary structures,including b-sheet [50]. The key ... tumor cells of a partly foldedvariant of LA bound to oleic acid [35,36], the ability of the protein to bind histones [37,38] and the bactericidalactivity of some of its chymotryptic peptides ... Da. The percentage of hydrogen exchange was calculated by the ratio between the observed mass of the protein at each time-point and the measured mass of the fully deuterated protein. Fully deuter-ated...
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Báo cáo khoa học " Lentinula edodes enhances the biocontrol activity of Cryptococcus laurentii against Penicillium expansum contamination and patulin production in apple fruits " ppt

... biocontrol activity of C. laurentii by complementing it with LF23 extract. The role of LF23extract consists of enhancing the antioxidant enzyme activity of the yeast colonising the apple wounds ... quantification of the P. expansum DNA present in the contaminated apples in the presence or in the absence of the different biocontro l agents. The quantity of DNA of P. expansum after 6 days of incubation ... biosynthesis is related to oxidative stress (Reverberi et al., 2005). The biocontrol effect of the culture filtrates of this basidiomycete isexerted by the antioxidant activity of some of the...
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Báo cáo y học: "Does eGFR improve the diagnostic capability of S-Creatinine concentration results? A retrospective population based study" ppsx

... does the eGFR II. The conversion of the S-Creatinine by any of the algorithms we tested does thus not contribute to a more effective understanding of the kidney function. The uncertainty of ... calculated from the year of birth to the year of sampling, irrespective of dates of birth or sampling. The population in neither of the catchment areas allowed singling out a group of African origin ... factor of about 0,45 (0,54 at 20 years and 0,42 at 80 years) and a magnifying constant factor (174-186) will drastically change the diagnostic power of the measurand. On the contrary, the algorithm...
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Báo cáo y học: "Physical anhedonia in the acute phase of schizophrenia" doc

... The severity of physicalanhedonia was significantly related to the diagnostic sub-category of non-paranoid schizophrenia, to the positivesymptoms score and to the negative symptoms score of the ... female(38%). Their mean age was 30.95 (± 8.91) years, (agerange 17 to 50 years). They had a mean of 12.6 (± 2.7)years of education, a mean duration of illness of 6.9 (±7.6) years and a mean duration of ... schizophrenia, consecutively admitted,with an acute episode of their illness, at the Eginition Hos-pital, Department of Psychiatry, University of Athens, dur-ing a one-year period were studied....
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Báo cáo y học: "Proteinase-3 as the major autoantigen of c-ANCA is strongly expressed in lung tissue of patients with Wegener’s granulomatosis" pptx

... Galle1and Werner Mayet41Department of Medicine, University of Mainz, Mainz, Germany2Institute of Pathology, University of Mainz, Mainz, Germany3Institute of Pathology, Professional Associations ... specimen. The upregulation of PR-3in the lung of WG patients may therefore reflect the selected organ injury, whereas the histological hetero-geneity may represent a multiplicity of concurrent immuneresponses ... weresequentially analyzed with light and fluorescentmicroscopy. The lectin of B. purpurea binds specificallyto pneumocytes type I, whereas the lectin of M. pomiferabinds to pneumocytes type II.Microscopic...
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Báo cáo y học: "Epidemiology, costs, and the economic burden of fibromyalgia" pptx

... – the latter amount was calculated prior to the approval of biologicals for the treatment of ankylosingspondylitis [8]. The study from Sicras-Mainar and colleagues is the firstcalculation of ... sub-sample of 200 patients, self-perceived health and well-beingwere evaluated by applying the Fibromyalgia ImpactQuestionnaire, the Brief Pain Inventory, and the EuropeanQuality of Life five-item ... highlight the urgent need both formore research (including pathophysiology and epidemiology) and for the acceptance of emerging treatment challenges.Despite the increasing awareness of fibromyalgia...
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Báo cáo y học: "Hypertrophy is induced during the in vitro chondrogenic differentiation of human mesenchymal stem cells by bone morphogenetic protein-2 and bone morphogenetic protein-4 gene transfer" pps

... separated by the proximity of the cells to the joint space and the bonerespectively, alignment of the chondrocytes along the arcades of Benninghoff [29] and by the appearance of hypertrophiccells. ... and CS4, one of the monomers of the polysaccharide portion of proteoglycan,showed significantly enhanced production of these cartilagematrix proteins at days 10 and 21 of culture in the aggregatesreceiving ... of earlyapoptotic cells, and the hydrolysis of the non-fluorescent 6-carboxyfluorescein diacetate (6-CFDA) to the green fluores-cent compound 6-carboxyfluorescein by the esterases of livingcells...
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Báo cáo y học: "Chemokine receptor expression and functional effects of chemokines on B cells: implication in the pathogenesis of rheumatoid arthritis" ppt

... pathogenesis of RA byantigen presentation, autoantibody production, and/orinflammatory cytokine production. Chemokines could enhance the accumulation of B cells in the synovium. The aims of thisstudy ... CCR7, CXCR3, CXCR4 or CXCR5, and the expression of the various markers was analyzed by flow cytometry. CD19+ B cells were gated, and the frequency of expression of each chemokine receptor is ... variety of foreign antigens [8]. Nota-bly, the severity of RA correlates with levels of rheumatoidfactor [9]. Furthermore, activated B cells produce inflamma-tory cytokines, such as TNF [10]. Therefore,...
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