Báo cáo y học: "A meta-analysis of the incidence of malignancy in adult patients with rheumatoid arthritis" doc

... studies comparing the incidence of malignancy in patients with RA versus the general population since thesemay be expected to provide a realistic perspective on risk in the clinical setting.Materials ... both within-study andbetween-study variation by incorporating the heterogeneity of effects in the overall analysis.ResultsA total of 2,093 articles were identified using the definedMedline ... meta-analysis [10,16,19].There have been a number of hypothesized explanations for the differences in the risk of certain malignancies in patients with RA compared with patients without the disease....

Báo cáo y học: "Comprehensibility, reliability, validity, and responsiveness of the Thai version of the Health Assessment Questionnaire in Thai patients with rheumatoid arthritis" potx

... weakly with four domains of the Thai HAQ (dressing and grooming, walking, grip, andactivity domains). The grip and walking domains of the ThaiHAQ also had weak correlations with the number of ... the Chinese and ArabicHAQs. For each domain of the Thai HAQ, only the walkingdomain had an ICC of greater than 0.85. The mean scores of each domain of the Thai HAQ and total scores in the secondadministration ... 0.75. The SRMs for the Thai HAQ com-pared with the other measures of RA disease activity areshown in Table 5.DiscussionApproximately 90% of the patients enrolled in this study werewomen. The...

Báo cáo y học: "Apoptosis is not the major death mechanism induced by celecoxib on rheumatoid arthritis synovial fibroblasts" pps

... writing of the manuscript. VD per-formed several experiments. MH participated in the analysis of the study and in the writing of the manuscript. BC and JMparticipated in the design of the study ... isunfavorable in the treatment of RA. The proposed local admin-istration of higher celecoxib concentrations in the synovialspace of the joint of arthritis patients [8] must therefore bereconsidered.Competing ... TRAIL by Annexin V staining/TO-PRO-3uptake. We have previously reported that 4 hours of co-cultur-ing with TRAIL resulted in apoptosis of approximately 30% of RA FLSs as determined by Annexin V...

Tài liệu Báo cáo Y học: A Raman optical activity study of rheomorphism in caseins, synucleins and tau New insight into the structure and behaviour of natively unfolded proteins pot

... ±Birkprotease inhibitors [5], metallothioneins [6], prothymosina [7], a bacterial ®bronectin-binding protein [8], the brainprotein a-synuclein together with the related proteinsb-synuclein and c-synuclein ... relies mainly on the evidence outlined above. In view of the c lose similarity of the ROA spectra of the casein, synuclein and tau proteins shown in t his paper, wehave reproduced in F ig. 1 ... aglobular protein c ontaining a similar number o f residues, asobserved in the caseins [3], synucleins [10], tau [14],prothymosin a [7] and the ®bronectin-binding protein [8],and also in typical chemically...

Báo cáo y học: "Birth order modifies the effect of IL13 gene polymorphisms on serum IgE at age 10 and skin prick test at ages 4, 10 and 18: a prospective birth cohort study" pps

... priori hypothesis was that the birth order effectmay interact with the genetic predisposition of the off-spring in influencing future atopic manifestations. In order to test this hypothesis, ... Each of these SNPs had a minor allelefrequency ≥ 19%.Using the Haploview program [26], three of the fivesingle nucleotide polymorphisms (SNPs) of the interleu-kin 13 gene were in a linkage ... r esult in a violation of the Hardy-Weinberg law. The genotypes of the five IL13 SNPs were in Hardy-Weinberg equilibrium a nd their allele frequencies werecomparable with those of other Caucasian...

Báo cáo y học: "Detailed analysis of the variability of peptidylarginine deiminase type 4 in German patients with rheumatoid arthritis: a case– control study" docx

... http://www.kursus.kvl.dk/shares/vetgen/_Popgen/genetik/applets/kitest.htm).ResultsDistribution of PADI4 haplotype combinations The frequencies of the PADI4 haplotype combinations found in our study are presented in Table 1. A detailed description of the variability of exons 2–4 of the ... anddrafted the manuscript. TH, RG, HK, GRB, and AS partici-pated in the coordination of the study and in drafting the man-uscript. TD participated in the design and coordination of the study, and ... clearly couldbe confirmed in our study. With the exception of haplotype 4, the frequencies of all otherPADI4 haplotypes in our control individuals were comparable with those reported by other...

Báo cáo y học: " Exercise therapy for the management of osteoarthritis of the hip joint: a systematic review" pot

... review.Interventions The interventions included (a) hydrotherapy, which was prima-rily of low intensity and involved walking, leg swinging, andmobility exercises; (b) land-based swinging, mobility, andstretching ... painincluded the VAS; the pain subscale of the Harris Hip Score;and/or the pain subscale of the Health Related Quality of LifeTable 1Level of evidence for evaluating the efficacy of exercise therapy in ... A key point in the guidelines concerns the intensity of exercise required. In this regard, information provided by authors in the currentreview was very limited. Often, the prescriptions of sets...

Báo cáo y học: "“I could cry, the amount of shoes I can’t get into": A qualitative exploration of the factors that influence retail footwear selection in women with rheumatoid arthritis" pdf

... that met the aims of the study. Following the initial interview, the interview sche-dule was further refined (Additional file 1).Generation of dataEach interview took place within the out-patient ... well-beingand quality of life (QOL). This study aimed to explore the perceptions of women with RA on their choice of footwear and identify the factors influencing footwearselection from within the ... podiatryclinic within the south east of England. Subjects wereinvited to participate on the basis that they met the cri-teria o utlined in Table 1, established through reviewingtheir clinical...

Báo cáo y học: "Clinical Strategy for the Management of Solid Pseudopapillary Tumor of the Pancreas: Aggressive or Less"

... 4-20). Nine patients had their tumors within the head, 2 in the body and 7 in the tail of the pancreas. Notably one patient was demonstrated to have liver metastasis. The predominant presenting ... complaint was abdominal pain (8/18). The rest of the patients were asymptomatic and tumors were de-tected incidentally during routine physical examina-tion. All these patients had no other ... the experience with the management of disseminated disease is very limited in the literature6, therefore, attention to the therapy strategy of this neoplasm in the future may allow a more...

Báo cáo y học: "A Practical Approach to Management of Chronic Hepatitis B"

... made in managing HBV infection, challenge remains in optimizing HBV therapy. First, further understanding HBV dynamics and correlation of the level of HBV replication with liver injury will be invaluable ... mortality. Although HBV treatment is usually highly indicated, clinical trials of HBV treatment remains limited in this special group of patients. The available preliminary studies indicated that the ... relatively contraindicated in this group of patients. The value of combination HBV treatment remains to be determined. Results on efficacy of IFN and LAM combination have been inconsistent. Combination...

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