... Davis3 and Edward Darzynkiewicz11 Division of Biophysics, Institute of Experimental Physics, Faculty of Physics, University of Warsaw, Poland2 Department of Chemistry, University of Warsaw, Poland3 ... mechanism of action on a molecularlevel, for the study of inhibition and for the design of effective inhibitors (in particular, human DcpS hasbeen selected as a therapeutic target for spinal ... or 3¢ oxygen of m7GuoThe kinetic parameters obtained for m27,2¢-OGpppG and m27,3¢-OGpppG demonstrated the crucial role of the 2¢-OH and 3¢-OH groups of the m7Guo moiety for C. elegans...