Báo cáo y học: "Reactive oxygen species induce expression of vascular endothelial growth factor in chondrocytes and human articular cartilage explants" pps
Báo cáo y học: "Reactive oxygen species induce expression of vascular endothelial growth factor in chondrocytes and human articular cartilage explants" pps
... http://arthritis-research.com/content/8/6/R189Page 1 of 8(page number not for citation purposes)Vol 8 No 6Research articleReactive oxygen species induce expression of vascular endothelial growth factor in chondrocytes and human articular ... and SIN-1 in chondrocytes. ConclusionBy amplifying distinct ROS-dependent destructive pathways in cartilage and joints, VEGF seems to have a crucial role in thedegeneration of articular cartilage ... expres-sion of VEGF in OA cartilage and reflect the ability of VEGF toenhance catabolic pathways in chondrocytes by stimulatingMMP activity and reducing natural MMP inhibitors, that is tis-sue inhibitors...
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Báo cáo y học: "The triterpenoid CDDO inhibits expression of matrix metalloproteinase-1, matrix metalloproteinase-13 and Bcl-3 in primary human chondrocytes" ppt
... evidence of a link in MMP-1 and Bcl-3 expression, and indicate that bothmolecules are similarly affected by CDDO.CDDO dose–response study in human primary chondrocytes To examine the effects of increasing ... that human primary chondrocytes have low basal expression of MMP-1, MMP-13 and Bcl-3, and that theyare increased in the presence of IL-1. Increasing doses of CDDO resulted in a decreased expression ... MMP-13, and Bcl-3, whichwere increased in the presence of IL-1 and inhibited byCDDO, following the trends observed in SW-1353 and human primary chondrocytes (data not shown).Effect of overexpression...
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báo cáo hóa học: " Reactive oxygen species drive herpes simplex virus (HSV)-1-induced proinflammatory cytokine production by murine microglia" ppt
... concen-trations of DPI or A PO used did not themselves induce microglial cell toxicity as determined by MTT ass ay and trypan blue staining.ROS drive cytokine and chemokine expression in virus-infected ... phosphorylated in response to viral infection and this activation was also blocked by inhibitors of NADPH oxidase. Finally, inhibition of either of these ROS-induced signaling pathways suppressed cytokine ... ROS in microglial cell cultures following viral infection. Virus-induced cytokine and chemokine mRNA and protein levels were assessed using real-time RT-PCR and ELISA, respectively. Virus-induced...
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báo cáo khoa học: "Reactive oxygen species-mediated apoptosis contributes to chemosensitization effect of saikosaponins on cisplatin-induced cytotoxicity in cancer cells" pdf
... as indicated in (A), and then stained with annexin V and PI followed by flowcytometry analysis. Early apoptosis is defined by Annexin V+/PI-staining (Q4) and late apoptosis is defined by ... Belinsky SA, Lin Y: A critical role of luteolin-induced reactive oxygen species in blockage of tumor necrosis factor- activated nuclear factor- kappaB pathway and sensitization of apoptosis in ... sensitizes docetaxel-induced cytotoxicity in human prostate cancer cells: Generation of reactive oxygen species and induction of apoptosis. Journal of carcinogenesis 2009, 8:9.26. Lin Y, Shi R, Wang...
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Báo cáo y học: " Rationale for one stage exchange of infected hip replacement using uncemented implants and antibiotic impregnated bone graft"
... survival following in vitro exposure of meticil-lin-resistant Staphylococcus aureus biofilms to the antibiotics clindamycin, daptomycin, linezolid, tigecycline and vancomycin. Int J Antimicrob ... Kanchanapoom T, Khardori N. In vitro activity of vanco-mycin, quinupristin/dalfopristin, and linezolid against intact and disrupted biofilms of staphylococci. Ann Clin Microbiol Antimicrob 2005;4:2. ... prostheses and effect on bacteria. J Infect Dis 1994;170(3):720-3. 39. Rose WE, Poppens PT. Impact of biofilm on the in vitro activity of vancomycin alone and in combination with tigecycline and...
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Tài liệu Báo cáo Y học: Enhancement by a-tocopheryl hemisuccinate of nitric oxide production induced by lypopolysaccharide and interferon-c through the upregulation of protein kinase C in rat vascular smooth muscle cells docx
... prolactin and growth hormone frompituitary cells in vitro [7]. Since then, various biologicalactivities of TS such as inhibition of acetylcholine esteraseactivity [8] and induction of apoptosis in ... the enhancing effect of TSon LPS/IFN-induced NO production is caused by enhance-ment of iNOS protein induction.Effects of a-T and its derivatives on the enhancementby TS of LPS/IFN-induced ... that TS induced upregulation of PKCa.DISCUSSION In this study, to obtain information about the mode of actions of TS, we examined the effect of TS on LPS/IFN-induced NO production in VSMC....
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Báo cáo Y học: Novel fish hypothalamic neuropeptide Cloning of a cDNA encoding the precursor polypeptide and identification and localization of the mature peptide pptx
... (LPXRFamide pep-tides) may be a conserved property of vertebrate brains, in particular the hypothalamus. In view of the immunohisto-chemical finding indicating that some of FMRFamide-likeimmunoreactive ... determined by a tandemmass spectrometric analysis (Fig. 3). Assignment of theobserved typical fragment ions, i.e. N-terminal (b) and C-terminal (y) ions, indicated that the amino acid sequence of ... Iwakoshi3, Hiroyuki Minakata3 and Kazuyoshi Tsutsui1,21Laboratory of Brain Science, Faculty of Integrated Arts and Sciences, Hiroshima University, Higashi-Hiroshima, Japan,2Core Research of Evolutional...
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Báo cáo y học: "Cellular mechanisms underlying the effects of an early experience on cognitive abilities and affective states." ppt
... 4).Effect of handling on BDNF immunoreactivity in the CA4 region of the hippocampusFigure 3Effect of handling on BDNF immunoreactivity in the CA4 region of the hippocampus. Handling resulted in increased ... byradioimmunoassay (RIA). Data were statistically analyzed by analysis of variance (ANOVA).Results: Neonatal handling increased the ability of male rats for spatial learning and memory. Italso resulted in increased ... associated with hypofunctioning of the sero-toninergic system. Recently BDNF has emerged as a major factor in the pathophysiology of depression: BDNF mRNAis increased in the rat brain following chronic...
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Báo cáo y học: " Egr-1 inhibits the expression of extracellular matrix genes in chondrocytes by TNF-induced MEK/ERK signalling" ppsx
... probably dueto the stability of the mRNAs.Figure 6Egr-1 DNA binding activity is increased by TNF-induced MEK1/2 sig-nalling in chondrocytesEgr-1 DNA binding activity is increased by TNF-induced ... Csf-1protein levels are also induced by TNF in chondrocytes [36]. In rat articular chondrocytes, macrophage Csf-1-induced sig-nalling increases its own expression and the expression of thematricellular ... modify gene expression in chondrocytes via MEK/ERK through the induction of Egr-1 DNA bindingactivity. Treatment of chondrocytes with IL-1 increases theEgr-1 protein and DNA binding, leading...
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Từ khóa: báo cáo y họcbáo cáo y học cổ truyềnmẫu báo cáo y học cổ truyềnbao cao y hoc colchicinphan ban luan trong bao cao y hoc co truyenbáo cáo khoa học y họcBáo cáo thực tập tại nhà thuốc tại Thành phố Hồ Chí Minh năm 2018Báo cáo quy trình mua hàng CT CP Công Nghệ NPVNghiên cứu tổ chức pha chế, đánh giá chất lượng thuốc tiêm truyền trong điều kiện dã ngoạiNghiên cứu vật liệu biến hóa (metamaterials) hấp thụ sóng điện tử ở vùng tần số THzNghiên cứu tổ chức chạy tàu hàng cố định theo thời gian trên đường sắt việt namBiện pháp quản lý hoạt động dạy hát xoan trong trường trung học cơ sở huyện lâm thao, phú thọGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANNGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWAN SLIDEQuản lý hoạt động học tập của học sinh theo hướng phát triển kỹ năng học tập hợp tác tại các trường phổ thông dân tộc bán trú huyện ba chẽ, tỉnh quảng ninhPhát hiện xâm nhập dựa trên thuật toán k meansNghiên cứu về mô hình thống kê học sâu và ứng dụng trong nhận dạng chữ viết tay hạn chếTìm hiểu công cụ đánh giá hệ thống đảm bảo an toàn hệ thống thông tinSở hữu ruộng đất và kinh tế nông nghiệp châu ôn (lạng sơn) nửa đầu thế kỷ XIXChuong 2 nhận dạng rui roGiáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtTÁI CHẾ NHỰA VÀ QUẢN LÝ CHẤT THẢI Ở HOA KỲ