... estrogen-signaling path-
Microscopy pictures illustrating the patterns of HER-2 immunostaining in breast carcinomaFigure 2
Microscopy pictures illustrating the patterns of HER-2 immunostaining in breast ... affecting Tunisian female patients with an inci-
dence of 23.6/100.000 inhabitants [1]. The data of our
registry show that women with breast carcinoma in Tuni...
... categories: no staining, or weak staining in fewer
than 10% of the tumor cells (0); weak staini ng in part of
themembraneinmorethan10%ofthetumorcells
(1+); complete staining of the membrane with weak ... leading cause of cancer death in women in
the USA [1] and its incidence is increasing i n many
countries, including Italy [2] thus representing a major
health problem. To da...
... urea.
Effect of dopamine on MPTP and MPP
+
induced
changes in kinetics of the aggregation of
a-synuclein
a-Synuclein was incubated in the presence of 100 lm
MPTP, along with 50 lm dopamine. Aliquots ... a-synuclein with
100 l
M neurotoxin; lane 2, a-synuclein with 200 lM neurotoxin;
lane 3, a-synuclein with 100 l
M neurotoxin and 50 lM dopamine;
lane 4, a-synuclein with...
... variations in identity
(for example ranging from 38–86% in Coprinopsis cine-
rea [27]). This natural diversity within in a single
organism can be used for protein engineering purpose.
In Trametes ... bias in the selec-
tion of recombination points. It has been suggested
that optimal recombination points allow swapping of
structural blocks [19], and combination of large pro-
te...
... deconvolution of spectra of the type
shown in Fig. 1A¢, with ML signals of a very low
intensity, was performed as a first step. Deconvolution
of spectra of the type shown in Fig. 1A, with intense
ML ... although
the starting intensity values and values at the minimum
were different, reflecting different pools of ML inside
the cells. By changing the seeding density, the minim...
... 1
after deducting basal and background values. Sepsis
resulted in a significant increase in the transcription of
the mRNA encoding iNOS in heart of iNOS
+ ⁄ +
mice.
The expression of iNOS mRNA was ... (Table 1). Interestingly, iNOS
– ⁄ –
mice showed
a significant decrease in nitrite level during sepsis, coin-
ciding with the mtNOS activity inhibition, that was
partially countera...
... and apply phonological
consistency in GPCs, including the roles of PCs in
PSCs in Chinese, plays an instrumental role in
learners’ competence in reading Chinese. Phono-
logical consistency is ... as hints to link
the meanings and writings of Chinese characters.
For instance, “河”(he2, river) [Note: Chinese char-
acters will be followed by their pronunciations,
denoted in...
... modifying h-toxin (per-
fringolysin O), a cholesterol-binding, pore-forming
cytolysin produced by Clostridium perfringens [18]. Ch
and BCh are noncytolytic derivatives of h -toxin that
bind specifically ... 30%
abolishes their binding to plasma membranes [17–19].
This is in remarkable contrast to cell binding by filipin,
another cholesterol-binding reagent. Filipin staining is
significantly...
...
how knowing the sort of each character is use-
ful when tokenizing a string of characters into
a string of words and when assigning parts -of-
speech to them, and our method of clustering
characters ... Unlike English being basically written in a 26-
character
alphabet, the domain of
possible characters
appearing in an average Japanese text is a set involving
tens of...
... changes that this binding interaction is proposed to
have, without in uencing the interaction with the G-protein.
Even though inactivating mutations associated with red hair
are common in the hMC1 receptors, ... G proteins to adenylate cyclase to stimulate
tyrosinase, the rate-limiting enzyme in the synthesis of both
classes of melanin pigments, eumelanin and phaeomelanin.
A low...