Báo cáo khoa học: "Male breast cancer: is the scenario changing" potx
Báo cáo khoa học: "Male breast cancer: is the scenario changing" potx
... tosupport the existing vast emerging knowledge about the disease.BackgroundMale breast cancer (MBC) comprises about 1% of all breast cancers but is found to be on the rise with the increasing ... AbstractBackground: The overall incidence of male breast cancer is around 1% of all breast cancers and is on the rise. In this review we aim to present various aspects of male breast cancer with ... revealedthat the risk of MBC to be significantly increased in maleswith the following characteristics; never married, benign breast disease, gynecomastia, Jewish or history of breast cancer...
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Tài liệu Báo cáo khoa học: Rotary F1-ATPase Is the C-terminus of subunit c fixed or mobile? docx
... and the complete a-helical C-terminusas held within the top of (ab)3. The rotary axis z was alignedalong the main axis of the shaft. The ‘bearing’ included atotal of 138 residues from the ... the C-terminal c portion within (ab)3(this work). This wouldmake the proposed unwinding of the a-helix in c afeatureof the wild-type enzyme and an integral element of the catalyticmechanism. ... the level where the torque was applied) is shown in Fig. 4. The right curve in this figure was obtained with a torque of56 pNÆnm and the left one with a torque of 112 pNÆnm, the arrows show the...
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Báo cáo khoa học: Arabidopsis thaliana CYP77A4 is the first cytochrome P450 able to catalyze the epoxidation of free fatty acids in plants potx
... electrontransfer during catalysis and probably to increase the stability of the expressed P450. Furthermore, there areonly three cytochromes P450 encoded by the yeast gen-ome. They are either not expressed ... sides of the hydroxyl functioncarrying the trimethylsilyl group. This fragmentationpattern is characteristic of the derivative of 11-hy-droxyoleic acid (x-7) (M = 384 gÆmol)1). The identifi-cation ... We determined the ste-reochemistry of this epoxide after purification andanalysis by HPLC using a chiral column. The radio-chromatogram of Fig. 3 shows that it is a mixture of the two enantiomers,...
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Báo cáo khoa học: "Granulosa cell tumor of the ovary and antecedent of adjuvant tamoxifen use for breast cancer" pot
... species-agonistversus partial agonist properties [16].ThemetaboliteEisgeneratedbythecatabolismoftamoxifen, which has a lower affinity for estrogen recep-tors than tamoxifen [17-19]. However the cis isomer ... probable that the association of granulosa cell tumor and the use oftamoxifen for breast cancer is just a random observationand there is no relationship between them.As mentioned earlier, the granulosa ... for the occurrence and thatwas only the second case in the literature despite that the t amoxifen being used by a large number of patientsaround the world with breast cancer. Tamoxifen is ananti-oestrogenic...
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Báo cáo khoa học: "Intraoperative radiation therapy in the treatment of early-stage breast cancer utilizing xoft axxent electronic brachytherapy" ppt
... attached the XB controller to the catheter, and inserted the radiationsource into the balloon. The radiation therapy was thenA CED is inserted through a small incision in the lateral breast and ... evaluate the bal-loon-to-skin distance and the degree of air and/or fluid in the breast tissue surrounding the balloon. For the pur-poses of this protocol, a minimum of 1-cm balloon toskin distance ... was then placed over the operative field,so that the radiation therapy could be delivered withoutcontaminating the field. The catheter end was passedthrough a hole in the drape and a FlexiShield™...
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Báo cáo khoa học: "Solitary fibrous tumor of the male breast: a case report and review of the literature" pptx
... mar-gins, histopatologic confirmation is the only sure differen-tial between benign and malignant disease. The differential diagnosis from cancer is the most impor-tant issue due to the very ... diagnosis. However, the two entities have substantially the same clinical and bio-logical behavior. Furthermore, differential diagnosis of a breast mass in a male routinely must distinguish fromgynecomastia, ... differen-tial diagnosis from breast cancer, but could not in differ-entiating from other mixed epithelial-mesenchymaltumors. For all these reasons, the exact diagnosis is fre-quently achieved...
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Báo cáo khoa học: " Linkage disequilibrium pattern of the ATM gene in breast cancer patients and controls; association of SNPs and haplotypes to radio-sensitivity and post-lumpectomy local recurrence" doc
... in the Norwegian breast cancer patients or riskof IBTR in the American breast cancer cases were thenSchematic illustration of the ATM geneFigure 1Schematic illustration of the ATM gene. The ... domain and PI3K domain [17] together with exonic information. (The size of the exons and the distance between them are not indicative of the sizes/distances in the gene/protein).ATGSer-1893PExonNO ... collected the clinical characteristics of adverse sideeffects of treatment for the Norwegian breast cancerwomen.- HE did the analysis of the results- All authors have read and approved the final...
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báo cáo khoa học: "Effective interventions to facilitate the uptake of breast, cervical and colorectal cancer screening: An implementation guideline." pps
... acquisition and analysis of the data; development of the initial draft manuscript, and manuscript revisions. All authors were responsible for the interpretation of the data; review of the draft ... independent from the funders with respect to the study design; collection, analysis, and interpretation of data; in the writing of the manuscript; and in the decision to submit the manuscript ... disentangle the multiple operational elements that define the various interventions to test those that are more and less effective, and further, to explain whether the cumulative impact of these...
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báo cáo khoa học: " Paget’s disease of the breast in a male with lymphomatoid papulosis: a case report" doc
... main hypotheses. The epidermotropichypothesis proposes that Paget’s cells originate fromductal epithel ium, from where they migrate towards the epidermis. This hypothesis is supported by the associa-tion ... carcinomain situ of the breast tissue or lymph node invasion.DiscussionPaget’s disease is an eczematous skin change of the nip-ple that is usually associated with an underlying breast malignancy ... underlying breast carci-nomainthemajorityofpatients.Thesecondhypothesis, the intraepidermal transformation theory,considers the presence of malignant keratinocytes thatoriginate from the areolar...
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báo cáo khoa học: "A nanocomplex that is both tumor cell-selective and cancer gene-specific for anaplastic large cell lymphoma" ppt
... dose.Interestingly, the increased PEI concentration withintumor tissues may enhance the in vivo therapeutic effectof the nanocomplex, but have no adverse effect on nor-mal tissues.ConclusionsIn this study, ... of both the siRNA and apta-mer that have complexed with the PEI-citrate nanocore.Further, the potential of the nanocomplex dropped to-25 ± 0.9 mV in the cell culture medium due to the high ... nanocore). The synthetic RNA-based CD30 aptamers and ALK siRNA were then incorporated onto the PEI-citrate nanocore to form the nanocomplex. B, When the functional RNA nanocomplex is added to...
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