... con-centrations of H2O2, they utilize the vacuole as the main source for Ca2+to be directed to the cytosol.Alkylhydroperoxide also induces a transientincrease in cytosolic Ca2+To determine whether ... forrelease of Ca2+from the vacuole to the cytosol. The YVC1 gene deletion drastically reduced the amplitude of the Ca2+burst, indicating that most of the Ca2+released into the cytosol after ... messenger in the eukaryotic cell, andthere is increasing evidence that cytosolic Ca2+entry in yeast is critical for survival under a variety of stress conditions, including hypo-osmotic or hyperosmoticshock...