Báo cáo y học: "Effect of adalimumab on neutrophil function in patients with rheumatoid arthritis" pps

... second aim of the study was to determine whetherdownregulation of phagocyte activities are involved in theanti-inflammatory activity of anti-TNF-α therapy. The lack of activity on phagocytosis, ... insight into a new and interestingmechanism of action of anti-TNF-α mAbs in the control of inflammatory arthritis.Keywords: adalimumab, neutrophils, rheumatoid arthritisIntroductionTumour ... migration soon after initiation of treatment with leflunomide or methotrexate in patients with rheumatoid arthritis: findings in a prospective, randomized,double-blind clinical trial in fifteen patients. ...

Báo cáo y học: " Effects of cyclophosphamide on pulmonary function in patients with scleroderma and interstitial lung disease: a systematic review and meta-analysis of randomized controlled trials and observational prospective cohort studies" ppt

... baseline and after 12months. In one study, one-half of the patients received oralCYC and one-half of the patients were treated with intrave-nous CYC [12]. We analyzed the two cohorts of patients ... appear to result in clinically significantimprovement of pulmonary function. Since none of the patients included in these studies were selected on the basis of pro-gression of ILD or the time ... bypulmonary function tests by conducting a systematic reviewand meta-analysis of randomized clinical trials and prospectiveobservational studies in patients with SSc treated with CYC.Materials...

Báo cáo y học: " Effects of asenapine on depressive symptoms in patients with bipolar I disorder experiencing acute manic or mixed " pot

... events andwithdrawn consent with asenapine, lack of efficacy andwithdrawn consent with placebo, and lack of efficacy with olanzapine (Table 1).EfficacyMontgomery-Asberg Depression Rating Scale ... depression receiving quetiapine or in patients with bipolar I depression receiving olanzapine/fluoxetine [21-23]. They are also within the range of values reported in a meta-analysis of controlled ... in combination with fluoxetine and quetiapine monotherapy areapproved by the US Food and Drug Administration forthe treatment of bipolar depression [8,9]. In patients with bipolar depression,...

Báo cáo y học: " A 1-year case-control study in patients with rheumatoid arthritis indicates prevention of loss of bone mineral density in both responders and nonresponders to infliximab" docx

... citation purposes)Vol 9 No 3Research articleA 1-year case-control study in patients with rheumatoid arthritis indicates prevention of loss of bone mineral density in both responders and nonresponders ... The findings suggest a defect in boneformation that may be explained, in part, by systemic inflamma-tion. Indeed, in one of our previous studies [16], uncouplingbetween bone destruction and ... with infliximab plus methotrexate, a decrease was observed only in bone resorption markers (urinary excretion of N-telopeptide of type I collagen and deoxypyridinoline) [18]. No effect on serumbone...

Báo cáo y học: "Analysis of skewed X-chromosome inactivation in females with rheumatoid arthritis and autoimmune thyroid disease" docx

... 1Distribution of X-chromosome inactivation patterns according to age in patients with rheumatoid arthritisDistribution of X-chromosome inactivation patterns according to age in patients with rheumatoid ... 13 years in HT patients and 44.6 ± 14years in GD patients) . The duration of the symptoms was 7.5± 4.6 years among the AITDs patients (6.8 ± 4.8 years in HT patients and 7.2 ± 4 years in GD patients) . ... 2Distribution of X-chromosome inactivation patterns according to age in patients with autoimmune thyroid diseasesDistribution of X-chromosome inactivation patterns according to age in patients with...

Báo cáo y học: "Dermatological conditions during TNF-α-blocking therapy in patients with rheumatoid arthritis: a prospective study" pps

... events con-sisted of skin infections, mostly fungal infections and folliculi-tis. The use of TNF-α-blocking therapy has raised concernsregarding an increased susceptibility to infections, as ... TNF-α-blocking therapy, a finding that couldsuggest at least a relative contribution to an increased vulner-ability to skin infections in the study population. In one patient,a bacterial superinfection ... afterinfusion. This will most likely not reflect the true ratio betweenacute and delayed reactions involving the skin, since acutereactions with skin involvement occur in 4% of the infusionsand...

Báo cáo y học: "Effect of smoking on lung function, respiratory symptoms and respiratory diseases amongst HIV-positive subjects: a cross-sectional study pptx

... effect of smok-ing on COPD development. Our study highlighted theimportance of smoking c essation in t he HIV-positivepopulation in terms of improving lung function andreducing respiratory symptoms, ... signedinformed consent, filled out a questionnaire, and under-went spirometry testing. The questionnaire containedinformation on demography, respirator y symptom s, andhistory of respiratory diseases, ... Lou Y, Kvale P, Rao A, Jordan M, Miller A, Glassroth J, Reichman L,Wallace J, Hopewell P: Pulmonary function tests in HIV-infected patients without AIDS. pulmonary complications of HIV infection...

báo cáo hóa học: " Effect of exacerbations on health status in subjects with chronic obstructive pulmonary disease" doc

... def-initions of an acute exacerbation in the literature vary[2,19,28-30], indicating that there is no clear consensus on the definition of an exacerbation. The application of adifferent definition of ... Twelve subjects with frequentexacerbations demonstrated a more apparent decline in health status.Conclusion: Although pulmonary function did not significantly decline during the 6-month period,acute ... Effect of exacerbation on quality of life in patients with chronic obstructive pulmonary disease. American journal of respiratory and critical care medicine 1998, 157(5 Pt 1):1418-1422.4. Jones...

báo cáo hóa học:" Effect of exacerbations on health status in subjects with chronic obstructive pulmonary disease" pdf

... prolonged study interval, then more sub-jects may have experienced exacerbations. Second,concerning the definition of an exacerbation, we selectedthe definition of an acute exacerbation of ... Twelve subjects with frequentexacerbations demonstrated a more apparent decline in health status.Conclusion: Although pulmonary function did not significantly decline during the 6-month period,acute ... decline in the Symptom scores in theSGRQ. In contrast, subjects without exacerbations did notshow any changes in excess of the minimal clinical signif-icant decline (0.5 units per question...

Báo cáo y học: " Management of HIV-1 associated hepatitis in patients with acquired immunodeficiency syndrome: role of a successful control of viral replication" ppsx

... possibly played by HIV-1 infection.BackgroundHuman immunodeficiency virus type-1 (HIV-1) infec-tion is commonly characterized by the presence of aprogressive depletion of CD4+T lymphocytes, ... clinical andlaboratory scheduled fol low-up. He discontinuedHAART for the onset of lipodistrophy signs, and on July2009 he returned t o our clinic, showing a worsening of clinical conditions ... amelioration of the clinical con-ditions was observed and after one month of therapy heshowed an immune-virological recovery with a persis-tently improvement of LFTs (Figure 1).ConclusionsInvolvement...

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