Báo cáo khoa học: "Atypical presentation of angiosarcoma of the scalp in the setting of Human Immunodeficiency Virus (HIV)" pdf

... presentation of angiosarcoma of the scalp in the setting of Human Immunodeficiency Virus (HIV)Poovandren S GovenderAddress: Department of Radiotherapy and Oncology, Nelson R. Mandela School of Medicine, ... over the scalp in the occipital region with erosion of the underlying bone.Extensive subcentimetre enhancing lymphadenopathywas noted in the anterior and posterior triangles of the neck with the ... age of 61 to 67 years [2,3].We report an atypical presentation of a case of angiosar-coma of the scalp occurring in association with HIV in a22 year old black female.Linkage studies of population-based...

Báo cáo khoa học: Relationship between functional activity and protein stability in the presence of all classes of stabilizing osmolytes ppt

... DGD° values in the presence of these osmolytes are given in Table 1. How-ever, DGD° values of RNase-A in the presence of alanine, serine, lysine, b-alanine, taurine and dimethyl-glycine have ... hydration of the protein domain is the driving force of protein stabiliza-tion or folding [3,4]. Furthermore, the effect of osmolytes on the functional activity of an enzyme hasalso been investigated ... glycine, l-alanine,l-proline, l-lysine, l-serine, b-alanine, taurine, sarcosine,dimethylglycine, glycine betaine, trimethylamine N-oxide,and cytidine 2¢-3¢ cyclic monophosphate were also obtainedfrom...

Báo cáo khoa học: "COMMON TOPICS AND COHERENT SITUATIONS: INTERPRETING ELLIPSIS IN THE CONTEXT OF DISCOURSE INFERENCE" ppt

... with in the treatment of VP-eUipsis, perhaps at the cost of some degree of the- oretical inelegance. However, this aspect was crucial for handling the gapping data, since the infelicity of gapping ... representations: in the case of parallel constructions, the source resided in the propo- sitional representation; in the case of non-parallel constructions, the source had been integrated into the dis- ... take the form of semantic representations retrieved by way of their corresponding node(s) in the syntax; the oper- ations performed on these representations are dictated by the nature of the...

Báo cáo khoa học: An E3 ubiquitin ligase, Synoviolin, is involved in the degradation of immature nicastrin, and regulates the production of amyloid b-protein doc

... ⁄ ))]. These results indicatethat a functional deletion of Synoviolin causes a change in the intracellular trafficking of NCT.Effect of Synoviolin on the production of AbNCT is one of the essential ... Synovi-lin-mediated ubiquitination also regulates the traffick-ing of NCT within the Golgi compartment, because the maturation of the sugar modification of the pro-tein occurs within the Golgi ... that the expression of Synoviolinenhances Ab generation. Further study of the mechan-ism underlying the enhancement of Ab generation bySynoviolin will clarify the interaction between the ubi-qutination...

Báo cáo khoa học: A novel factor XI missense mutation (Val371Ile) in the activation loop is responsible for a case of mild type II factor XI deﬁciency doc

... activation loop at the N-terminus of the catalyticdomain, are notable. In the zymogen FXI, Ile371 is exposed to the solvent, while in the activated FXI it is inserted into the protein. The picture ... (1993) The linkage between binding of the C-terminal domain of hirudin and amidase activity in human alpha-throm-bin. Biochem J 289, 475–480.45 Baglia FA & Walsh PN (1996) A binding site ... interference with the binding of the activator to the FXI zymogen.There are some examples of inherited coagulationdisorders in which one of the peptide linkages requiredfor the proteolytic zymogen...

Báo cáo khoa học: "A Feedback-Augmented Method for Detecting Errors in the Writing of Learners of English" docx

... taken into account in this pa-per, the feedback corpus contains further useful in- formation. For example, we can obtain trainingdata consisting of instances of errors by compar-ing the feedback ... 1(a)?modified by one of the words in Table 1(b)?modified by one of the words in Table 1(c)?Figure 1: Framework of the tagging rulesTable 1: Words used in the tagging rules(a) (b) (c) the indefinite article ... errors since they are based on the articlesand the distinction between singular and plural.Finally, the tagged instances are stored in a filewith their surrounding words. Each line of it con-sists...

Báo cáo khoa học: Calcium-dependent protein–protein interactions induce changes in proximity relationships of Cys48 and Cys64 in chicken skeletal troponin I ppt

... R.S. (1997) Mapping of asecond actin-tropomyosin and a second troponin C binding sitewithin the C terminus of troponin I, and their importance in the Ca2+-dependent regulation of muscle contraction. ... Segment V,containing an a-helical structure, binds to the hydrophobiccleft of the N-terminal domain of TnC.There are two cysteine residues (Cys48 and Cys64) in the N-terminal end of TnI from both ... facilitates the binding of TnC to the thin ﬁlament. The other twoN-terminal sites (I and II) bind Ca2+exclusively butwith lower afﬁnity (K % 105M)1). Binding of Ca2+to the N-terminal sites...

Báo cáo khoa học: Unchanged thymidine triphosphate pools and thymidine metabolism in two lines of thymidine kinase 2-mutated ﬁbroblasts docx

... involvement of TK2 in the phosphorylation of thymidine in both cell lines inferred above (Table 1)from the inhibition of thymidine phosphorylation in vitro caused by KIN109. The speciﬁc radioactivity of ... decreased the speciﬁc radioactivity of dTTP after 20 min of incubation to 75% in Ca cellsand to 25% in Pa cells (Fig. 2B). As BVDU inhibited the expansion of the dTTP pool in the two lines to the same ... in the in situ phosphorylation of thymidine, Ca and Pa lines were also incubated in the presence of 1 lM BVDU added 15 min before [3H]thymidine, and the incubationwas continued for 5 min...

Báo cáo khoa học: Gliadain, a gibberellin-inducible cysteine proteinase occurring in germinating seeds of wheat, Triticum pdf

... Expression of gliadain in maturingand germinating wheat seeds. (A) Northernblotting analysis of gliadain in maturing andgerminating seeds. Aliquots of 10 lg of totalRNA were loaded into each ... detected in the aleuronelayer and also in the endosperm region in the vicinity of the embryo (Fig. 3A). Expression of gliadain in the endosperm was limited to the region near the embryo in which ... known to play roles in storageprotein digestion during germination, catabolysis of intracellular proteins, and in the processing of prepro-proteins in maturation [1–10]. In germination, manyhydrolytic...

Báo cáo khoa học: "Embryonic Intermediate Filaments, Nestin and Vimentin, Expression in the Spinal Cords of Rats with Experimental Autoimmune Encephalomyelitis" pdf

... region showedintense nestin immunostaining. At the recovery stage of EAE (day 21 PI), the nestin immunostaining pattern wassimilar to the pattern at the peak stage of EAE, with fewernestin-positive ... cells. In the present study, the expression patterns of nestin andvimentin in the spinal cords of rats w ith experimentalautoimmune encephalomyelitis (EAE) and the response of cells containing ... were found to express nestinand/or vimentin in rats with EAE. This finding is in partEmbryonic Intermediate Filaments, Nestin and Vimentin, Expression in the Spinal Cords of Rats with Experimental...

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