... of the THO com-plex for the expression of long genes [14], the GLAMratios of the two THO mutants were dramaticallyreduced when compared with the wild type (Fig. 6). The absence of effect of ... several plasmids containing the PHO5coding region transcribed under the control of the GAL1 promoter, but differing in the length of their3¢-UTR. To increase the length of the 3¢-UTR weinserted ... mutant lacking the histone acetyltransferase subunit of the elongator[26] (Fig. 2C). In all these cases, the GLAM ratios of the mutants were, at most, 50% of the wild-type ratiosand, therefore,...