Báo cáo khoa học: "Ultrasound-guided central venous catheterization in cancer patients improves the success rate of cannulation and reduces mechanical complications: A prospective observational study of 1,978 consecutive catheterizations" pps
... deaminase contains 1
equivalent of Zn
2+
per subunit. Thus, the early part of
the riboflavin biosynthetic pathway in plants is similar
to that of eubacteria, rather than that in fungi and
archaea. ... synthases using
NADPH as cosubstrate results in progressive disap-
pearance of substrate signals and the appearance of a
singlet at 42 p.p.m., reflecting the 1¢ carbo...
... connected
with the facts that modification of particular sites in
the genome of living cells is naturally stochastic on
the one hand, and in uenced by the actual structural
and functional state of the given ... ability of the particular p53
target site to accommodate the cisplatin IACs. The
higher the probability of formation of the cisplatin
IACs within...
... l-3,4-
dihydroxyphenylalanine (l-DOPA), which is the rate-
limiting step in synthesis of the catecholamines DA,
norepinephrine and epinephrine. TH consists of four
identical subunits that contain a C-terminal catalytic
domain ... may provide a negative charge that
interacts with the amino group of DA and the pyridine
moiety of NMNorsal in opposition to the bide...
... hybridization,
4
buttheincreaseinRAMY
mRNA level occurs prior to that of the Amy2 mRNA level
in the GA-treated aleurone tissues. These data suggest that
RAMY may act as a trans-acting protein and is probably
involved ... specifically to the O2S elemen t. We
have also determined the importance of the amino acids
within the binding domain of RAMY protein and analyzed
t...
... with large phase IV clinical trials, meta analyses,
data base registry validation of ap proaches including quality of life and cost benefit analyses, safety, and head-to-
head clinical trials investigating ... the Diagnosis, Therapy and Management of Hereditary
Angioedema is reviewed in light of the newly published phase III Clinical trials for prevention and therapy of...
... between
peptide and RNA, the overall charge of the peptide
was crucial for the activity, as the replacement of sin-
gle basic amino acids with alanine resulted in the
annealing rate constant decreasing by a ... RNA chaperone also has annealing
activity, it can catalyze the strand displacement event
in two ways: by destabilizing edges and bulges, and
by favoring...
... similar to that
in Asp141 of Met8P.
The idea of NirF being a dehydrogenase is appealing
because of the presence of a putative nucleotide-bind-
ing motif in the N-terminal of the protein sequence
and ... Andreas
Schlueter and Alfred Phu
¨
ler at the University of Biele-
feld are thanked for their kind gift of plasmid pMS255.
Dr Katalin di Gleria at The Wea...
... 7p12-13
and codes for a 170kDa receptor tyrosine kinase. All
ERBB proteins have four functional domains: an
extracellular ligand-binding domain; a transmembrane
domain; an intracellular tyrosine kinase ... kinase domain; and a
C-terminal regulatory domain [2]. The extracellular
domain is subdivided further into four domains. The
tyrosine kinase domain consists of an N-lobe an...
... I, Kobayashi K, Yamazaki K,
Asahina H, Inoue A, Hagiwara K, Sunaga N,
Yanagitani N, Hida T et al. (2009) Combined Survival
Analysis of Prospective Clinical Trials of Gefitinib for
Non-Small Cell ... non–small cell lung cancer
Imatinib was designed to compete with ATP at the
ATP-binding site within the tyrosine kinase domain of
ABL, which is activated as a result of the chr...
... transactivation domain. The DNA-bind-
ing domain is responsible for DNA binding specificity
and dimerization, and the ligand-binding domain is
responsible for binding of the ligand and associated
induced ... of hormone-respon-
sive genes in a hormone-dependent manner [63]. Most
NRs share a common structural organization that
includes a DNA-binding domain, a ligand-bin...