Báo cáo y học: "Serum levels of autoantibodies against monomeric C-reactive protein are correlated with disease activity in systemic lupus erythematosus" potx

Báo cáo y học: "Serum levels of autoantibodies against monomeric C-reactive protein are correlated with disease activity in systemic lupus erythematosus" potx

Báo cáo y học:
... anti -C-reactive protein autoantibody; CRP, C-reactive protein; mSLEDAI, modified systemic lupus erythematosus disease activity index; n.s., not significant;SLEDAI, systemic lupus erythematosus disease ... density; PBS = phosphate-buffered saline; SLE = systemic lupus erythematosus; SLEDAI = systemic lupus erythematosus disease activity index; SLICC = Systemic Lupus International Collaborating Clinics; ... consumption of CRP by ICs [35]. With this in mind we find the high fre-quency (4 of 4) of anti-CRP in patients with ongoingkidney involvement interesting, given the pathogeneticimplications of ICs in...
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Báo cáo y học: "Serum levels of biomarkers of bone and cartilage destruction and new bone formation in different cohorts of patients with axial spondyloarthritis with and without tumor necrosis factor-alpha blocker treatment" ppt

Báo cáo y học:
... ankylosing spondylitis; BALP: bone-specific alkaline phosphatase; BASDAI: bath ankylosing spondylitis disease activity index; CRP: C-reactive protein; ELISA: enzyme-linked immunosorbent assay; ... are a good parameter to indicate disease activity in AS while there are some contradictory results about the use of MMP-3 serum levels to indicate disease activity. Finally, BALP seems not tobe ... Keyser F, Veys EM, Yu DT: Serum levels of matrix metalloproteinase 3 and macrophage colony-stimulat-ing factor 1 correlate with disease activity in ankylosingspondylitis. Arthritis Rheum 2004,...
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Báo cáo y học: " Serum levels of hyaluronic acid and chondroitin sulfate as a non-invasive method to evaluate healing after cartilage repair procedures" pptx

Báo cáo y học:
... gadolinium-enhanced MRI of cartilage (dGEMRIC)and T1-rho and T2-mapping have promise to assess tissuequality by indirectly measuring glycosaminoglycan content[3,4]. However, these techniques are ... colleagues investigatedthe use of monoclonal antibodies and enzyme-linked immuno-sorbent assay to quantify serum levels of CS and HA,respectively, in a dog model. They followed two groupstreated with ... chondroitin sulfate (CS) for theircorrelation with tissue quality after cartilage repair with autologouschondrocytes versus subchondral drilling in a dog model. Theyreported better tissue quality in...
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Báo cáo y học: "Serum levels of matrix metalloproteinases -1,-2,-3 and -9 in thoracic aortic diseases and acute myocardial ischemia" potx

Báo cáo y học:
... a large fam-ily of proteolytic enzymes containing a metal in theirorganic structure playing key roles in degradation of pro-teins in extracellular matrix and in tissue remodelingthrough complicated ... increase compared tohealthy individuals [16]. This is in contradiction with theresults of the present study. Nambi et al. investigated the levels of MMP-1 in patients with coronary artery disease [17]. ... levels of MMP-3 in atheroscleroticplaques in any kind of aortic aneurysm [15,19,20]. High levels of MMP-3 have also been reported in the bloodserum of patients with coronary arteries aneurysm...
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Báo cáo sinh học: " Serum levels of preS antigen (HBpreSAg) in chronic hepatitis B virus infected patients" potx

Báo cáo sinh học:
... entry [20]. Since preS mainly exist in the DNA-containing Dane HBV particles, detection of HBpreSAgpresent in serum of HBV patients may have a clinical value in management of HBV infection. In ... Gu1, Ming Luo1,3 and Xiaofeng Zheng*1,2Address: 1National Laboratory of Protein Engineering and Plant Genetic Engineering, Peking University, Beijing, 100871, China, 2Department of Biochemistry ... protein anti-HBsanti-preS45.0kDa35.0kDa25.0kDaL protein M protein S protein anti-HBsanti-preS45.0kDa35.0kDa25.0kDaComparison of the binding ability of preS and preS1 to anti-preS by...
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Báo cáo hóa học: " Serum levels of preS antigen (HBpreSAg) in chronic hepatitis B virus infected patients" pptx

Báo cáo hóa học:
... entry [20]. Since preS mainly exist in the DNA-containing Dane HBV particles, detection of HBpreSAgpresent in serum of HBV patients may have a clinical value in management of HBV infection. In ... Gu1, Ming Luo1,3 and Xiaofeng Zheng*1,2Address: 1National Laboratory of Protein Engineering and Plant Genetic Engineering, Peking University, Beijing, 100871, China, 2Department of Biochemistry ... protein anti-HBsanti-preS45.0kDa35.0kDa25.0kDaL protein M protein S protein anti-HBsanti-preS45.0kDa35.0kDa25.0kDaComparison of the binding ability of preS and preS1 to anti-preS by...
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Báo cáo y học: "Elevated expression of caspase-3 inhibitors, survivin and xIAP correlates with low levels of apoptosis in active rheumatoid synovium" potx

Báo cáo y học:
... patientassessment of pain and global score of disease activity andphysician score of global disease activity (all on visual ana-logue scales). In addition, C-reactive protein (CRP), erythro-cyte sedimentation ... macrophage lineage cells, CD55for synovial fibroblasts in the synovial lining layer, CD22 for Bcells and CD3 for T-lymphocyte lineage cells.Detection of apoptosis by TUNEL stainingTerminal deoxynucleotidyl ... roles in determining whether apoptosis occurs. Apoptosis in active RAmay be important as a way of limiting inflammation by reducingthe number of inflammatory cells and could potentially be atherapeutic...
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Báo cáo y học: "Decreased levels of soluble amyloid β-protein precursor and β-amyloid protein in cerebrospinal fluid of patients with systemic lupus erythematosus" ppsx

Báo cáo y học:
... TGF-β levels observed may support a notion of an ongoing anti-inflammatory response counteracting tissue injury caused byCNS lupus. Keywords: amyloid precursor protein, β-amyloid protein, cerebrospinal ... amyloidogenic protein with anti-inflammatoryproperties. In the CNS lupus group, intrathecal levels of TGF-β were significantly increased compared with those of SLE patients without overt CNS disease ... well as of lupus patients without MRI-verified brain pathology. Thisfinding, together with increased intrathecal levels of TGF-β, indicates an ongoing destructive parenchymatousprocess in the...
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Báo cáo y học: "A combination of autoantibodies to cyclic citrullinated peptide (CCP) and HLA-DRB1 locus antigens is strongly associated with future onset of rheumatoid arthritis" potx

Báo cáo y học:
... the combination of SE genecarriage and anti-CCP antibodies or an RF of any isotype, in comparison with individuals not having any of the factorsor having any one of them separately. In particular, ... Nishioka Y, Sekine A, Iida A, Takahashi A,Tsunoda T, Nakamura Y, Yamamoto K: Functional haplotypes of PADI4, encoding citrullinating enzyme peptidylarginine deimi-nase 4, are associated with rheumatoid ... understanding of theevents triggering the disease would be achieved, therebycreating the possibility of developing and testing preventivemeasures and of instituting therapy at earlier stages of dis-ease...
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Báo cáo y học: " Clinical evaluation of autoantibodies to a novel PM/Scl peptide antigen" doc

Báo cáo y học:
... thedevelopment of sophisticated profile assays containing multi-ple different antigens. This may improve the diagnosis of avariety of disorders, especially of autoimmune diseases sincefor most of those ... II) was assayed for anti-PM1-α peptide reactivity in the ELISA. The results were com-pared with the known reactivity of these sera with the recom-binant proteins [18]. When all assays were adjusted ... the peptide reactivityand the reactivity of the sera with the recombinant proteins.Not surprisingly, the strongest correlation was observed with the anti-PM/Scl-100 reactivity (Fig. 1). Whereas...
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