Báo cáo y học: "The value of sensitive imaging modalities in rheumatoid arthritis pdf

... years have witnessed the emergence of a newparadigm in the treatment strategy for RA, involving earlyCommentaryThe value of sensitive imaging modalities in rheumatoid arthritis Peter C TaylorThe ... joints permit an increasingly refinedanalysis of anatomic detail. However, further research using these sensitive imaging technologies isrequired to delineate pathophysiological correlates of ... RA = rheumatoid arthritis; US = ultrasonography. Arthritis Research & Therapy Vol 5 No 5 TaylorIntroductionEvaluation of disease activity and structural damage tojoints in rheumatoid arthritis...

Báo cáo y học: "New classification of HLA-DRB1 alleles in rheumatoid arthritis susceptibility: a combined analysis of worldwide samples" docx

... Mixed lymphocyte cultures in rheumatoid arthritis. JClin Invest 1976, 57:1148-1157.4. Korendowych E, Dixey J, Cox B, Jones S, McHugh N: The Influ-ence of the HLA-DRB1 rheumatoid arthritis shared ... estimations than in European ones. Molokhia and McKeigue previously pointedout the difficulty brought up by admixture in investigating theetiology of rheumatic diseases, notably for RA [16]. ... contribution of the HLA-DRB1gene was previously analyzed in terms of RA severity and in terms of autoantibody production such as anti-cyclic citrulli-nated peptide (anti-CCP) antibodies and anti-deiminatedhuman...

Báo cáo y học: " the Value of Serum Biomarkers (Bc1, Bc2, Bc3) in the Diagnosis of Early Breast Cancer"

... in at least 10% of invasive carcinoma cells or presence of mem-branous staining in less than 30% provided that the staining is intense (++) Score 3: Presence of intense staining surrounding ... Training and Research Hospital 1st Biochemistry Clinic 3. Dokuz Eylül University Institute of Oncology 4. İzmir Atatürk Training and Research Hospital 1st Pathology Clinic  Corresponding ... studied in terms of tumoral development and inflammatory response rather than malignancy. Another study by Mathelin et al. included a total of 89 patients. Bc1a and Bc1b defined by the authors...

Báo cáo y học: "The value of animal models in predicting genetic susceptibility to complex diseases such as rheumatoid arthritis" ppsx

... moreefficient by minimizing the cost of genotyping. By creating1,000 recombinant inbred lines from eight founder strainsthat are first intercrossed to mix the genomes and theninbred, a permanent ... A20 cDNA induced bytumor necrosis factor alpha encodes a novel type of zincfinger protein. J Biol Chem 1990, 265:14705-14708.11. Feldmann M, Maini SR: Role of cytokines in rheumatoid arthritis: an ... QTL analysis [86]. Unfortunately, the use of many of these resources is limited by the strict MHC dependency of most arthritis models.Another interesting prospect is the use of microarray data,...

Báo cáo Y học: The presence of a helix breaker in the hydrophobic core of signal sequences of secretory proteins prevents recognition by the signal-recognition particle in Escherichia coli doc

... variable in the interactionwith SRP [14,41,42]. However, the hydrophobicity of cysteine is even slightly lower than that of glycine [37].Therefore, the cross-linking of (G-10C)prePhoE to P48indicates ... preprotein istranslocated by an insertion–deinsertion cycle of SecA intothe SecYEG translocon [8]. Energy for the translocationprocess is provided by ATP hydrolysis by SecA [8,9] and bythe ... via the SRPinstead of the SecB pathway could be explained by theincreased hydrophobicity of the hydrophobic core of themutant signal sequence, because hydrophobicity was previ-ously reported...

Báo cáo y học: "The importance of measuring psychosocial functioning in schizophrenia" pps

... feature of schizophrenia,and may be to some extent independent of other symp-toms [21]. They may precede the onset of illness,becoming more pronounced in the prodrome and earlyyears following ... importance of measuringpsychosocial functioning in schizophrenia. Annals of General Psychiatry2011 10:18.Brissos et al. Annals of General Psychiatry 2011, 10:18http://www.annals-general-psychiatry.com/content/10/1/18Page ... func-tioning, psychopathology and cognition.Psychosocial functioning in schizophreniaDeficits in psychosocial functioning are a core feature of schizophrenia. They can be observed in its early stages,*...

Báo cáo y học: "The role of regulatory T cells in antigen-induced arthritis: aggravation of arthritis after depletion and amelioration after transfer of CD4+CD25+ T cells" doc

... Germany) intraperitoneally. Arthritis was induced by intra-articular injection of 100 µgmBSA in 25 µl phosphate-buffered saline (PBS) into theright knee joint cavity. Arthritis severity was ... and/or draining lymph nodes, forinstance in tolerated allografts [28], in Langerhans isletsand pancreatic lymph nodes in inflammation-induced dia-betes [29], in chronically inflamed skin in a Leishmaniainfection ... higher in CD25-depleted mice. (b) Haematoxylin and eosin stained frontal knee joint sections were scored on a 0–3 point scale at day 14 of AIA for each of the following: severity of synovial hyperplasia,...

Báo cáo khoa học: "The value of metabolic imaging to predict tumour response after chemoradiation in locally advanced rectal cancer" doc

... managem ent of patientswith cancer has increased with the introduction of thismodality into clinical practice [5].After our preliminary experience with this techniquedeal ing with staging of colorectal ... fusing of function and morphologic data has increased the sensi-tivity and specificity in restaging of various malignanttumours including LARC after CRT.Recently, de Geus-Oei [8] analysed in an ... period of at least 6 hoursprior to FDG injection, patients received an intravenousinjection of 18-FDG, with the activity normalized for theweight of the patient, followed by an injection of physiolo-gic...

Báo cáo y học: "Trends towards an improved disease state in rheumatoid arthritis over time: influence of new therapies and changes in management approach: analysis of the EMECAR cohort" ppt

... Spain. Throughout the follow-up of theEMECAR cohort, the percentage of patients without anyDMARD declined while the frequency of patients on combinedtherapy increased. In addition, combination ... [http://www.ser.es/practicaClinica/Guias_Practica_Clinica.php].21. Godinho F, Godfrin B, El Mahou S, Navaux F, Zabraniecki L, Can-tagrel A: Safety of leflunomide plus infliximab combinationtherapy in rheumatoid arthritis. ... der, Linden Svan der: COBRA combination therapy in patients with early rheumatoid arthritis: long-term structural benefits of a briefintervention. Arthritis Rheum 2002, 46:347-356.15. Young...

Báo cáo y học: "The importance of localizing pulmonary veins in atrial septal defect closure" ppsx

... discovery of three additional anomalies, namely Interrupted Inferior Vena Cava (IIVC),Scimitar syndrome, and systemic arterial supply of the lung. Postoperatively these finding were confirmed by CTangiography. ... diagnosis in thefield of congenital heart surgery cannot be overempha-sized. To this end many centers routinely use Intrao-perative Trans-Esophageal Echocardiography (ITEE).Mayo clinic group in ... pulmonary vein; arrow head = hepatic vein,which drains into right atrium. B - The arterial phase depicts theanomalous systemic artery (arrow) arising from the celiac trunk andintending to supply...

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