... joints, and it results in the accumu-lation of leukocytes within the synovial tissue (ST) andsynovial fluid (SF). The inflammatory infiltrate consists pre-dominantly of B lymphocytes, T lymphocytes ... are another cell type expressing CXCR5 in the synovium. There have been several reports ofendothelial cells in the RA synovium expressing chemokinereceptors, including CXCR3 and CXCR4, in addition ... control (Dako, Ely, UK). The sec-tions were rinsed with PBS and incubated with biotinylatedsecondary antibody. The antibody binding was detectedusing reagents in the Vectastain ABC Elite kit...