... sur-vival, including tumor grade, depth of invasion, tumorsize, and the status of the resection margin. In this study,depth of invasion and tumor grade seemed to affect the DFS and OS rates. ... be considered for patients with theserisk factors.Although the combination of chemotherapy with sur-gery and RT has improved cure rates in some other head and neck cancers, its role in the ... contributionsSJS and KCK developed the ideas for these experiments, performed much of the work, and drafted the manuscript. JC, WSK, GEK, CGL, and ECC designed the study, collected the data and interpreted the...