Báo cáo khoa học: " Expression of placenta growth factor mRNA in the rat placenta during mid-late pregnancy" pptx

Báo cáo khoa học: "Expression of nitric oxide synthase isoforms in the porcine ovary during follicular development" ppsx

... localization of neuronal (nNOS), endothelial (eNOS), and inducible (iNOS) isoforms of nitric oxidesynthase (NOS) in the ovaries of pigs. The intensity of staining is indicated by (-), where staining ... follicles. Taking all of the findings into consideration, the observed differential expression of the three NOS isoforms in the ovarysuggests a role for nitric oxide in modulating reproduction in pigs.Key ... expression of nNOS in the ovary. The aim of this study, therefore, was to compare the expression patterns of eNOS, iNOS, and nNOS in the porcine ovary during follicular development in order toelucidate...

Báo cáo khoa học: " Expression of placenta growth factor mRNA in the rat placenta during mid-late pregnancy" pptx

... ...

Báo cáo khoa học: Mutation of epidermal growth factor receptor is associated with MIG6 expression docx

... forindicating the intrinsic kinase activity of EGFR,regardless of tissue type.ResultsLigand-induced transcriptional signatures of EGFR-WT and L858R in the absence or presence of EGFR kinase ... drugresistance. The results obtained demonstrate differ-ences in EGF-stimulated transcription in the absenceor presence of Iressa in all cell lines tested, and showthat the expression dynamics of the ... EGFR expression levels because the overexpression of EGFR has often been linked tohigh EGFR kinase activity. Therefore, ERRFI1 expres-sion in various cancer cell lines was investigated usingthe...

Báo cáo khoa học: " Assessment of Epidermal Growth Factor Receptor (EGFR) expression in human meningioma" docx

... (21-40% of the sample exhibiting staining); 3 (41-60% of the sample exhibiting staining); 4 (61-80% of the sample exhibiting staining), and 5 (81-100% of the specimen stained). The findings of the ... of the sampleexhibiting staining); 2 (21-40% of the sample exhibitingstaining); 3 (41-60% of the sample exhibiting staining); 4(61-80% of the sample exhibiting staining), and 5 (81-100% of ... only in their behavior but also in their expression of EGFR[33]. Lusis et al in a report evaluating the expression of EGFR in 41 meningiomas identified a relatively higherincidence of EGFR expression...

Báo cáo khoa học: Control of transforming growth factor b signal transduction by small GTPases pot

... in the N-terminal Mad homology 1 domain of all Smads binds to importin-b in the case of Smad3and importin-a in the case of Smad4, while mutation of the NLS blocks the ability of these proteins ... 2009)doi:10.1111/j.1742-4658.2009.07031.x The integrated roles of small GTPases in executing the transforming growth factor b (TGFb) signaling pathway have attracted increasing atten-tion in recent years. In this review, ... memory of Xenopus embryonic cells toactivin A exposure, the critical step in determining the duration of activin A signaling was the time spent by the ligand ⁄ receptor complexes in the endo-lysosomalpathway....

Báo cáo khoa học: Activation of hepatocyte growth factor activator zymogen (pro-HGFA) by human kallikrein 1-related peptidases docx

... cleavage of the Arg407–Ile408 bond in response to tissueinjury, generating the two-chain active form consisting of a disulﬁde-linked 66 kDa long chain and 32 kDalight chain [10,11]. The light chain ... matrixproteins such as ﬁbronectin, laminin, and type IV col-lagen, which facilitate the cellular invasiveness at the invasion front [37]. Insulin-like growth factor- bindingproteins are also ... 2008 FEBS 1007 factor- binding proteins would increase the pericellularconcentration of insulin-like growth factor, and thiscould eventually stimulate invasive growth of tumorcells [21,40]....

Báo cáo khoa học: Folding of epidermal growth factor-like repeats from human tenascin studied through a sequence frame-shift approach pdf

... folding in vivo The folding in vivo of an extracellular protein containin gdisulﬁde-rich domains, the low-density lipoprotein recep-tor, has s hed new light on the folding process in the livin ... support this hypothesis. The disappearancerates of the reduced frame-shifted peptides, including EGF-14, are all within the same order of magnitude. The disappearance rate of the starting (reduced) ... whether inter-rather than intra-repeat disulﬁde bonds form. In otherwords, we forced misfolding to occur within shortpeptides that nevertheless maintain their native sequence.Oxidative foldingBecause...

báo cáo khoa học: " Expression of MICA, MICB and NKG2D in human leukemic myelomonocytic and cervical cancer cells" potx

... ELISA; the concentration of MICA AND MICB increased during the first five days in culture (Figure 6).CALO and INBL proliferate in response to MICA and MICBAfter we detected the expression of MICA, ... leupeptin, 1-μg/ml pepstatin, 1-μg/mlaprotinin and 1% Triton X-100). The insolub le materialwas pelleted (15,000 × g for 15 min) at 4°C.Total protein content in the lysates was determinedusing the ... evalu-ated the amounts of these proteins in their respectiveconditioned media (CM). Using ELISA, we determinedthat MICA and MICB were indeed secreted into the CMfromthefirstdayofculture(Figure1B).Wedidnot...

Báo cáo khoa hoc:" Expression of estrogen and progesterone receptors in vestibular schwannomas and their clinical significance" docx

... immunofluorescencehistochemical staining to detect estrogen-binding activityand found 1 of 8 tumors had estrogen-binding activityand the intensity of the staining was found to be muchgreater in ... muchgreater in the tumors from the 5 women. They concludedthat estrogen may promote the growth of acousticschwannomas by inducing proliferation of vascularendothelium, with a resultant increase in tumor ... wrote the paper; VA: Co-investigator - helped in doing the study and collecting the data; AKJ: Co-investigator -collected the articles; RP: Co-investigator - provided the advice and coordinated the...

Báo cáo y học: " Expression of transforming growth factor- in chronic idiopathic cough" pdf

... volunteers. These indicate that there is anincreased amount of TGF expressed in the airways thatcould be involved in the airway wall remodelling of chronic cough. This is supported by the findings of ... fluid the levels of growth factors, such as transforming growth factor- (TGF), which may be involved in subepithelial fibrosis[14], and of the neurotrophins such as brain-derived neu-rotrophin ... purposes)ence of TGF mRNA expression in the airway epithelialcells and airway smooth muscle cells using the technique of laser capture for the first time, allowing us to specifi-cally pinpoint the expression...

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