... populations, leading to mental disorders andneuropathologies.MNB ⁄ DYRK 1A has also been implicated in variousaspects of late neuronal differentiation. Thus,MNB ⁄ DYRK 1A kinase activity was upregulated ... literature classified MNB ⁄ DYRK 1A as a nuclear protein kinase because it contained a bipartitenuclear translocation signal and MNB ⁄ DYRK 1A- tagged peptides indeed localized in the nucleus of transfected ... Gwack Y, Sharma S, Nardone J, Tanasa B, Iuga A, Srikanth S, Okamura H, Bolton D, Feske S, Hogan PGet al. (2006) A genome-wide Drosophila RNAi screenidentifies DYRK-family kinases as regulators...