... 4. Department of Statistics, University of Connecticut, Storrs, CT, USA 5. Department of Medicine, Division of Rheumatology, Allergy and Immunology, School of Medicine, University of California ... trial of subjects with OA, taking a single oral daily dose of 40 mg UC-II on an empty stomach prior to bedtime for 42 consecutive days, an average of 26% reduction of pain was noted in four of ... ingredients Use of concomitant prohibited medication (narcotics, oral NSAIDs, topical NSAIDs) within four weeks of randomization Use of acetaminophen or ibuprofen within 7 days of randomization...