... CorporationEURASIP Journal on Bioinformatics and Systems BiologyVolume 2007, Article ID 49478, 10 pagesdoi:10.1155/2007/49478 Research Article Analysis of Gene Coexpression by B-Spline BasedCoD ... Tompkins, and R. W.Davis, “Significance analysis of time course microarray exper-iments,” Proceedings of the National Academy of Sciences of theUnited States of America, vol. 102, no. 36, pp. 12837–12842,2005.[19] ... Thecoefficient of determination (CoD), on the other hand, iscapable of uncovering nonlinear relationship in microarraydata and suggesting the directionality, thus has been used inprediction analysis of...