Báo cáo sinh học: " Inhibition of human immunodeficiency virus type-1 (HIV-1) glycoprotein-mediated cell-cell fusion by immunor (IM28)" docx
Báo cáo khoa học: ` Inhibition of human ether a go-go potassium channels by 2+ Ca ⁄calmodulin binding to the cytosolic N- and C-termini potx
... inhibited by Ca 2+ ⁄ CaMat low Ca 2+ concentrations [6] and low CaM concen-trations (Fig. 1). As for CNG channels, hEAG1harbors CaM -binding motifs in the N- and C-terminaldomain and both of them are ... channels and of KCNQ channels. On the onehand they are activated by membrane depolarization and do not inactivate as do KCNQ channels. On the other hand EAG channels harbor a C-terminal puta-tive ... C-terminal domain of Ca 2+ -free CaM,i.e. apoCaM. The activation of these channels is medi-ated by conformational changes in the CaM ⁄ SK2 com-plex induced by binding of at least one Ca 2+ ion to the...
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Báo cáo khoa học: Inhibition of human MDA-MB-231 breast cancer cell invasion by matrix metalloproteinase 3 involves degradation of plasminogen docx
... nm of duplicate experiments performed in quadruplet.Ó FEBS 2002 MMP -3 inhibits MDA-MB- 231 invasion (Eur. J. Biochem. 269) 4479 Inhibition of human MDA-MB- 231 breast cancer cell invasion by matrix ... MMP -3 caninhibit tumour cell BM invasivity in an established model of human breast cancer cell invasion in vitro. MMP -3 inhibition of invasion was dependent upon plasminogen, involved MMP -3 activity ... considered significant at P £ 0.05.RESULTS Inhibition of MDA-MB- 231 invasion by MMP -3 Human MDA-MB- 231 breast cancer cells constitutivelyexpress, MMP-9, low level MMP -3, TIMP-1, TIMP-2, uPAand t-PA but...
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báo cáo sinh học:" Assessment of human resources for health using cross-national comparison of facility surveys in six countries" ppt
... compiled in advance. Thiswould entail strengthening of routine administrative human resources information systems, including thecompleteness and timeliness of facility staffing returns,which are often ... [http://www.who.int/gender/documents/Genderworkhealth.pdf].BioMed CentralPage 1 of 9(page number not for citation purposes) Human Resources for Health Open AccessResearch Assessment of human resources for health using cross-national ... – information on health system personnel is often fragmented or incomplete. Health facility assessments are being increasingly used tomeasure and monitor indicators of health worker per-formance,...
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báo cáo sinh học:" Assessment of human resources management practices in Lebanese hospitals" pptx
... of quantitative data included questions on level of education, qualifications in HR management, experi-ence and training in HR management, and plans for con-tinuing education in the realm of ... whethercontinuing education at Lebanese hospitals is strategicand in line with training needs of staff.Many respondents revealed that hospitals are engaging in financial incentives in an effort ... chal-lenges. For instance, the most commonly reported strategywas offering continuing education and training foremployees (19.6%). Moreover, 54.6% of respondentsreported offering continuing education...
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Báo cáo sinh học: " Clearance of an immunosuppressive virus from the CNS coincides with immune reanimation and diversification" pptx
... CentralPage 1 of 16(page number not for citation purposes)Virology JournalOpen AccessResearch Clearance of an immunosuppressive virus from the CNS coincides with immune reanimation and diversificationHenning ... adaptive immune repertoire, which includes the mobilization of CD4+ T cells and B cells, is responsible for the eventual clearance of clone 13 from the CNS, and, quite possibly, the periphery. Immune ... post-infection, and this was associated with a rapid decline in virus from the periphery. Coincident with this " ;reanimation phase" was a massive influx of CD4 T and B cells into the CNS and a...
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Báo cáo sinh học: " Inhibition of phosphorylated c-Met in rhabdomyosarcoma cell lines by a small molecule inhibitor SU11274" pdf
... Access Inhibition of phosphorylated c-Met in rhabdomyosarcoma cell lines by a small molecule inhibitor SU11274Jinxuan Hou1,2, Jixin Dong3, Lijun Sun4, Liying Geng3, Jing Wang3, Jialin ... G,Rahman A, Chen G, Staten A, Griebel D, Pazdur R: Approval summary:imatinib mesylate in the treatment of metastatic and/or unresectablemalignant gastrointestinal stromal tumors. Clin Cancer ... control. All slides wereindependently analyzed by two investigators. The stain-ing score was calculated from the stai ning intensity andpercent age of positive staining cells. The staining inten-sity...
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Báo cáo sinh học: "Inhibition of mitotic kinase Aurora suppresses Akt-1 activation and induces apoptotic cell death in all-trans retinoid acid-resistant acute promyelocytic leukemia cells" ppt
... H Open AccessInhibition of mitotic kinase Aurora suppresses Akt-1 activation and induces apoptotic cell death in all-trans retinoid acid-resistant acute promyelocytic leukemia cellsDuo-Rong ... VX-680 inhibits activation of Aur-A and induces monopolar spindle in NB4-R2 cells. (A) VX-680 inhibited phosphorylation of Aur-A at Thr288 in NB4-R2 cell line. Cells were incubated with increasing ... stem cells and induces leukemia in mice. Blood 2010, 115:1406-15.doi:10.1186/1479-5876-9-74Cite this article as: Xu et al.: Inhibition of mitotic kinase Aurora suppresses Akt-1 activation and induces...
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Báo cáo sinh học: " Effects of transplantation with bone marrowderived mesenchymal stem cells modified by Survivin on experimental stroke in rats" potx
... as: Liu et al.: Effects of transplantation with bone marrow-derived mesenchymal stem cells modified by Survivin on experimental stroke in rats. Journal of Translational Medicine 2011 9:105.Submit ... Open Access Effects of transplantation with bone marrow-derived mesenchymal stem cells modified by Survivin on experimental stroke in ratsNan Liu1*, Yixian Zhang1,2, Lin Fan3, Mingzhou Yuan4, ... transplantation with bone marrow-derived mesenchymal stem cells (MSCs) modified by Survivin (SVV).Methods: MSCs derived from bone marrow of male Sprague-Dawley rats were infected by the self-inactivelentiviral...
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Báo cáo sinh học: " Inhibition of human immunodeficiency virus type-1 (HIV-1) glycoprotein-mediated cell-cell fusion by immunor (IM28)" docx
... Percent-age fusion was divided into three classes: 56–00% of thesurface covered by syncytial = fusion; partial inhibition of fusion: < 10% of the surface is covered by syncytial = P; inhibition of ... (1.15) I (3.52)§F = 50–60% of the surface is covered by syncytia; P = partial inhibition of fusion: < 10% of the surface is covered by syncytia; I = inhibition of syncytia formation.TF228.1.16 ... The fusion of 293/CD4+ cells with TF228.1.16 cells was completelyinhibited by a lower dose of IM28 than was the fusion of SupT1 cells with TF228.1.16 cells (data not shown). The fusion of TF228.1.16...
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Báo cáo sinh học: " Typing of human rotaviruses: Nucleotide mismatches between the VP7 gene and primer are associated with genotyping failure" pdf
... UV-light. Nucleotide mismatches in the primersFigure 2 Nucleotide mismatches in the primers. The target sequence is the VP7 gene of G1 Bangladeshi strains. The G1 rotavirus VP7 gene specific primers ... 1 of 5(page number not for citation purposes)Virology JournalOpen AccessResearch Typing of human rotaviruses: Nucleotide mismatches between the VP7 gene and primer are associated with genotyping ... differences between the target region of the respective genes and the primer sequences used for typing led to the genotyping failure [1,10,11,17]. The Dhaka hospital of ICDDR,B, situated in the centralBangladesh,...
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Báo cáo sinh học: " Transmission of human hepatitis C virus from patients in secondary cells for long term culture" pot
... negative cga gac ctc ccg ggg cac tcg caa gca cccHCV 3 negative acg cag aaa gcg tct agc cat ggc gtt agtHCV 4 negative tcc cgg ggc act cgc aag cac cct atc aggHutLA2 positive ggg ccg ggc atg aga cac ... positive cat gat gca cgc tct acg aga c HCV 10.1 positive ctg tga gga act act gtc ttc acg cagHCV 10.2 positive cac tcg caa cca ccc tat cagHCV 1 negative act gtc ttc acg cag aag cgt cta gcc atHCV ... or cells) . Since only one cell producinginfective virus can be enough to achieve transmission, both methods can be used to successfully culture HCV. In vitro propagation of HCV in cultured cellsFigure...
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Báo cáo sinh học: " Inhibition of Henipavirus fusion and infection by heptad-derived peptides of the Nipah virus fusion glycoprotein" doc
... membrane fusion. Peptides Inhibition of Hendra virus and Nipah virus infection by N-terminal and C-terminal pegylated heptad peptidesFigure 6 Inhibition of Hendra virus and Nipah virus infection by ... availability of NiV in the Inhibition of Hendra virus and Nipah virus infection by capped heptad peptidesFigure 5 Inhibition of Hendra virus and Nipah virus infection by capped heptad peptides. Vero ... moietyHypothetical models of the transmembrane (F1) glycoproteins of Hendra virus and Nipah virusFigure 1Hypothetical models of the transmembrane (F1) glycoproteins of Hendra virus and Nipah virus. The...
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báo cáo hóa học:" Inhibition of human immunodeficiency virus type-1 (HIV-1) glycoprotein-mediated cell-cell fusion by immunor (IM28)" docx
... CentralPage 1 of 6(page number not for citation purposes)Virology JournalOpen AccessResearch Inhibition of human immunodeficiency virus type-1 (HIV-1) glycoprotein-mediated cell-cell fusion by immunor ... Percent-age fusion was divided into three classes: 56–00% of thesurface covered by syncytial = fusion; partial inhibition of fusion: < 10% of the surface is covered by syncytial = P; inhibition of ... glycoproteinsyncitiafusion membraneHIV-1AbstractBackground: Immunor (IM28), an analog of dehydroepiandrosterone (DHEA), inhibits human immunodeficiency virus type-1 (HIV-1) by inhibiting reverse...
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Báo cáo y học: "Inhibition of human immunodeficiency virus type-1 by cdk inhibitors" pdf
... AccessInhibition of human immunodeficiency virus type-1 by cdk inhibitorsIrene Guendel1,3†, Emmanuel T Agbottah2†, Kylene Kehn-Hall3, Fatah Kashanchi1,3,4*AbstractCurrent therapy for human immunodeficiency ... binding of cdk9 /cyclin T1 to TAR RNA [21].Recently, a growing body of evidence has indicated therole of yet another cyclin /cdk complex, namely cyclinE /cdk2 , in Tat activated transcription. Cyclin ... al.: Inhibition of human immunodeficiency virus type-1 by cdk inhibitors. AIDS Research andTherapy 2010 7:7.Submit your next manuscript to BioMed Centraland take full advantage of: • Convenient...
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Báo cáo y học: "Autoprocessing of human immunodeficiency virus type 1 protease miniprecursor fusions in mammalian cells" pptx
... 20 01, 75(20):9762-9770.doi :10 .11 86 /17 42-6405-7-27Cite this article as: Huang and Chen: Autoprocessing of human immunodeficiency virus type 1 protease miniprecursor fusions in mammalian cells. AIDS Research and Therapy ... 7:27http://www.aidsrestherapy.com/content/7 /1/ 27Page 4 of 10 RESEA R C H Open AccessAutoprocessing of human immunodeficiency virus type 1 protease miniprecursor fusions in mammalian cellsLiangqun Huang, Chaoping ... Kimmel AR, Jerina DM: Kinetics andmechanism of autoprocessing of human immunodeficiency virus type 1 protease from an analog of the Gag-Pol polyprotein. Proc Natl Acad SciUSA 19 94, 91( 17):7970-7974.6....
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