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báo cáo hóa học: " The minimal important difference of the hospital anxiety and depression scale in patients with chronic obstructive pulmonary disease" pot

báo cáo hóa học:

báo cáo hóa học: " The minimal important difference of the hospital anxiety and depression scale in patients with chronic obstructive pulmonary disease" pot

... Using the regression equation and the minimal important differ-ence of the anchors (0.5 points for the CRQ[15] and 8points for the FT[23]) we estimated the minimal impor-tant difference of the ... difference of the HADS it is not known[11] The concept of the minimal important difference the smallest difference in the outcome of interest thatinformed patients or their proxies perceive as important and ... trials without the understanding that the point estimate is the best estimate of the minimal important difference and that the limits of the 95% confidence intervals are sample size dependent. Since...
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Báo cáo hóa học:

Báo cáo hóa học: " Autologous tumor-derived heat-shock protein peptide complex-96 (HSPPC-96) in patients with metastatic melanoma" potx

... and tested in cancer and melanoma patients since the 1960s[11,12]. After cleaning the skin with acetone, 2000 and 50 μgofDNCBin100μl of acetone were layered on the skin of the volar aspect of ... orexpanded in culture other than as specified a bove dur-ing the ELISPOT assay. The mean values of s pots in replicate wells were determined, and the frequency of IFNg-secreting cells in tumor-stimulated ... Administration In the Melanoma Medical Oncology Clinic at M. D.Anderson, a vial of HSPPC-96 was thawed and the con-tents drawn up into a tuberculin syringe and injectedintradermally into either the patient’s...
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báo cáo hóa học:

báo cáo hóa học: " What determines subjective health status in patients with chronic obstructive pulmonary disease: importance of symptoms in subjective health status of COPD patients" pdf

... in this group of patients is relevantfor the treatment of COPD, and for the care and rehabili-tation of patients. To this end, the aim of the present studywas to explore the determinants of ... symptoms with the St George Respiratory Questionnaire and the Hospital Anxiety and Depression Scale, physical function with the Incremental Shuttle WalkingTest, and subjective health status with the ... phlegm/sputum, shortness of breath, wheezing and chest trouble [18,21]. Anxiety and depression Anxiety and depression were measured with the Hospital Anxiety and Depression Scale (HADS). HADS is...
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Báo cáo hóa học:

Báo cáo hóa học: " Phase I clinical trial of the vaccination for the patients with metastatic melanoma using gp100derived epitope peptide " pot

... frequency of induced IFN-g-producingcells in association with the number of the vaccinations. In P2, a significant increase of the frequency of induc-tion of IFN-g-producing cells was observed during ... IFN-g.IFN-g-producing cells wereinduced with the gp100 -in4 stimulation on the PBMCstaken from the patients (P1, P2, P3, and P4) after the vaccination. The PBMCs of P1 showed an incrementalincrease in the ... of Tokyo).Vaccination The enrolled patients were injected subcutaneou sly with 1 mg of the gp100 -in4 emulsified in 1 ml of IFA (Mon-tanide ISA-51, Seppic, France) into the skin at the axil-lary or inguinal...
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báo cáo hóa học:

báo cáo hóa học: " Factor structure of the Hospital Anxiety and Depression Scale in Japanese psychiatric outpatient and student populations" pdf

... the affective and cognitive aspects of anxiety and depression. The HADS consists of 14 items; the anxiety (HADS-A) and depression (HADS-D) subscales each include 7 items. The conciseness of the HADS ... wordingissues previously mentioned. The revision of the HADSshould be started from such language issues in advance of the rescoring. In the original scoring system, however, the two of the depression ... that of the HADS-A in this study. Therefore, itshould be noted that the validity and reliability of the HADS-D subscale is inferior to the HADS-A subscale in the current Japanese version of the...
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báo cáo hóa học:

báo cáo hóa học: " Cultural adaptation into Spanish of the generalized anxiety disorder-7 (GAD-7) scale as a screening tool" pot

... in two dif-ferentiated factors: one containing all GAD-7 items plusitems in the HADS Anxiety subscale, and the other con-taining the items in the HADS Depression subscale. The comparison of ... Test:atrecruitment, the GAD questionnaire was administeredto the sample of patients and controls together with three other instruments: the Hamilton Anxiety Scale (HAM-A) [14], the Hospit al Anxiety and Depression Scale ... clin-ical criteria. Since a cut-off point of 10 yields excellentsensitivity and specificity values, and is in line with the cut-off value proposed by the original authors of the scale [22], this...
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Báo cáo khóa học: Endoplasmic reticulum-associated degradation of glycoproteins bearing Man5GlcNAc2 and Man9GlcNAc2 species in the MI8-5 CHO cell line docx

Báo cáo khóa học: Endoplasmic reticulum-associated degradation of glycoproteins bearing Man5GlcNAc2 and Man9GlcNAc2 species in the MI8-5 CHO cell line docx

... min of preincubation in 0.175 mMGlc (T0 h) and chased in the culture medium containing 5 mMGlc and 5 mMManfor 3 and 6 h (T3 h and T6 h, respectively). The cells were then submitted to the ... 2003Most of the evidence for the occurrence of degradationsignals involved in ERAD has been obtained by studying the effect of inhibitors of demannosylation (kifunensine and deoxymannojirimycine) ... [13]; the high turnover rate of lipid donors. Theseadaptive events involve only the lipid intermediate donors and not the glycans bound to the protein moiety. Thus the fate of glycoproteins bearing...
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báo cáo hóa học:

báo cáo hóa học:" RAGE (Receptor for Advanced Glycation Endproducts), RAGE Ligands, and their role in Cancer and Inflammation" pptx

... survival in the setting of stress. Understanding the molecular structure and function of it and its ligands in the setting of inflammation is critically important in understanding the role of this ... other substrates [67,69]. It remains to bedetermined if the action of the A-box is the result of com-petitive inhibition by binding to other substrates or inter-fering with the ability of the ... Met1 as the initial Met in the immatureprotein) can form an internal disulfide bond within the A-box. The A-box and the oxidation state of these twocysteines play an important role in the ability...
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báo cáo hóa học:

báo cáo hóa học:" Comprehensive molecular etiology analysis of nonsyndromic hearing impairment from typical areas in China" doc

... testing of deaf Chinese patients. Furthermore, the molecular defects of about 66% of the patients with nonsyndromic hearingimpairment in China remain to be identified.Competing interests The ... mutation in the mtDNA tRNAser(UCN)gene. All of the above 11 patients had a clear history of aminoglycoside use. None of the remaining 68 patients with history of aminoglycoside use had mutations in ... hormone testing and ultrasound scan of the thyroidto examine the function and structure of the thyroidinstead of perchlorate discharge testing, a routine methodused for examining thyroid function...
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báo cáo hóa học:

báo cáo hóa học: " Effect of exacerbations on health status in subjects with chronic obstructive pulmonary disease" doc

... 0.01) domains of the CRQ, and in the Symptom scores (OR = 2.11, p = 0.01) in the SGRQ.Only the SGRQ Symptom scores with worse baselinescores showed a significant influence on the decline in health ... statistically and clinically significantdeclines in three domains of the CRQ (Fatigue, Emotion, and Mastery), and in all three components and the totalscores of the SGRQ (Figure 3 &4). These results ... decline in the Symptom scores in the SGRQ. In contrast, subjects without exacerbations did notshow any changes in excess of the minimal clinical signif-icant decline (0.5 units per question for the...
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