... forself care and routine activities; feelings of being a burdento family; and feeling sad, hopeless, and helpless.Table 1 includes the description of the transfusion inde-pendent state and transfusion ... Debilitating symptoms of MDSinclude fatigue, pallor, infection, and bleeding; with com-monly associated laboratory findings of anemia, neutro-penia, and thrombocytopenia [2,3]. Due to its lowincidence ... experienced in various aspects of their HRQOL.Each health state card included different levels of severity/intensity of problems on the following specific aspects of main HRQOL domains: reliance...