báo cáo hóa học:" Optical imaging of the peri-tumoral inflammatory response in breast cancer" docx

... In vivo optical imaging of a MMTV-PymT mouse after intravenous injection of DiD-labeled monocytesFigure 4(a) In vivo optical imaging of a MMTV-PymT mouse after intravenous injection of DiD-labeled ... cells, and the red peak represents labeled cells.(a) In vivo optical imaging of a control FVB/n mouse after intravenous injection of DiD-labeled monocytesFigure 3(a) In vivo optical imaging of a ... took part in all the experiments and was the primary writer of the manuscript. RJK was involved in the in vivo data gathering. ST performed or participated in both the in vitro and in vivo studies....

Báo cáo hóa học: "Morphologic complexity of epithelial architecture for predicting invasive breast cancer survival" ppt

... assess the generalizability of the results [21]. The process con-sisted of splitting the original sample of 379 patients intoa training set of 190 patients and a validation set of 189patients using ... coefficient. The shrinkagecoefficient was calculated as the difference between the AUCs of the training and validation sets. The smaller the shrinkage coefficient, the more confidence one can have in the ... stain to tissuespecimens in order to highlight and isolate the histo-logical structures of interest. In this case, thesestructures include the outlines of the epithelial com-ponents comprising...

báo cáo hóa học:" High correlation of the proteome patterns in bone marrow and peripheral blood blast cells in patients with acute myeloid leukemia" pot

... 12-D pattern of the silver stained gel image of the master gel image. 2-D pattern of the silver stained gel image of a master gel image containing the spot information of all investigated samples. ... involved in the formation and maintenance of the histo-architecture.[19]103 Plasmonogen activator inhibitor-2 (PAI-2) Involved in the regulation and inhibition of binding between urokinase-type ... electrophoresis, the gels were fixed in 50% ethanol,and 10% acetic acid for 12 hours.Silver stainingProteins were visualized using the silver staining methodemploying a modification of the method of Heukeshovenaccording...

báo cáo hóa học:" Heterogeneous activation of the TGFβ pathway in glioblastomas identified by gene expression-based classification using TGFβ-responsive genes" pptx

... among the training set, suggesting clear distinctionbetween the two subgroups. The rest of the glioma sam-ples were then subjected to SVM as the test set. Table 1summarized the results of the ... shown in box plots. Y-axis is the expression level of SERPINE1 in log2 scale. The black arrow indicates the mean expression level of SERPINE1 in each type of gliomas. Red spots indicate the ... ZYX). Integrinshave been shown to mediate the activation of TGFβ [41]and TGFβ is known to regulate the expression of cell adhe-sion molecules including integrins [42,43]. Interestingly,the...

báo cáo hóa học:" Molecular analysis of the apoptotic effects of BPA in acute myeloid leukemia cells" potx

... the double treatment, showing an increase of the G1 peack at low dose BPA (30 μM) and an increase of the G2-M fraction of cells at the highest concentration of BPA (100 μM). Differently, in the ... might consider the induction of apoptosis as an interesting anti-cancer action, on the other side we have to keep in mind that these effects mightalso be elicited in normal cells in the different ... at the present, our data suggest that the contactor the assumption of BPA might increase the effects of aon-going treatment in humans, apart, of course, havingeffects on its own. Finally, the...

báo cáo hóa học:" Epigenetic control of the ubiquitin carboxyl terminal hydrolase 1 in renal cell carcinoma" doc

... It is comprised of enzymes involved in the protein ubiquitination/deubiq-uitination as well as of the subunits of the 20S proteasomethat degrades ubiquitin-conjugated proteins [1,2]. Ubiq-Published: ... characterized by methylation of some of the CpG dinucleotides within the core region of the UCHL1 promoter while other CpG sites remain unmeth-ylated. In addition strong methylation of the promoterDNA ... region, as defined by either methylation of allCpG sites or only few unmethylated CpG sites within the core region of the CpG islet, was found in the RCC cellline MZ1851LN. The status of the methylation...

báo cáo hóa học: " Factor structure of the Hospital Anxiety and Depression Scale in Japanese psychiatric outpatient and student populations" pdf

... Further studies on the response bias of the Japanese version of the HADS are needed. In addition, item 10 needs to be more closely examined in order to determine the consistency with the other ... such language issues in advance of the rescoring. In the original scoring system, however, the two of the depression items (item 6 and 10) may under-mine a precise evaluation of depressive level ... longitudinal research study wouldallow the temporal stability of the HADS to be examined.Finally, the construct overlap between the HADS and the other assessment instruments was not examined. The HADS...

báo cáo hóa học: " Telephone reliability of the Frenchay Activity Index and EQ-5D amongst older adults" pptx

... test-retest reliability study of the Barthel Index, the Rivermead Mobility Index, the Notting-ham Extended Activities of Daily Living Scale and the Frenchay Activities Index in stroke patients. Disability ... administration of these instruments at both the individual item level andoverall score. Within the EQ-5D instrument, the intraclasscorrelation coefficients and limits of agreement (Table 3)indicated ... telephone administration of these instruments is a valid method of obtaining thisinformation from elderly patients in the community. The ability to collect this survey based information via the tel-ephone...

báo cáo hóa học: "Rasch analysis of the Multiple Sclerosis Impact Scale (MSIS-29)" pot

... provides further evidence for the internal validity of the physical and psychological impactscales of the MSIS-29, supporting their use in clinical andresearch settings as a measure of HRQoL to ... shouldalso be utilized. Further evaluation of the response format of the scales should be undertaken to examine the deci-sion made in this study to rescore the response categories of the MSIS-29-PHYS ... would include the administration of the original and revised version of the MSIS scoring to the same people to compare their validity.Longitudinal studies should also be undertaken to assessthe...

báo cáo hóa học: " Measurement properties of the Dizziness Handicap Inventory by cross-sectional and longitudinal designs" docx

... dizziness, rather than the origin of dizziness, should probably be the indication for using the questionnaire. It was favourable that the participants in the present study reported a wide range of ... shows the mean change in scores from the first to the secondmeasurement, and the flanking dotted lines, the limits of agreement, take the mean change in scores as well as the SDDind into consideration.Responsiveness The ... studies [27], while in our study of test-retest reliabil-ity, only 27 participants were included. SDDind estimated in sample 2 were in line with the initial findings in the DHI (SDD ≥ 18) [1]....

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